CESAB_ORYSJ
ID CESAB_ORYSJ Reviewed; 860 AA.
AC Q69XK5;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 13-SEP-2004, sequence version 1.
DT 03-AUG-2022, entry version 85.
DE RecName: Full=Putative cellulose synthase A catalytic subunit 11 [UDP-forming];
DE EC=2.4.1.12;
DE AltName: Full=OsCesA11;
GN Name=CESA11; OrderedLocusNames=Os06g0600550, LOC_Os06g39970;
GN ORFNames=P0457B11.25, P0486H12.12;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
CC -!- FUNCTION: Catalytic subunit of cellulose synthase terminal complexes
CC ('rosettes'), required for beta-1,4-glucan microfibril crystallization,
CC a major mechanism of the cell wall formation. {ECO:0000250}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[(1->4)-beta-D-glucosyl](n) + UDP-alpha-D-glucose = [(1->4)-
CC beta-D-glucosyl](n+1) + H(+) + UDP; Xref=Rhea:RHEA:19929, Rhea:RHEA-
CC COMP:10033, Rhea:RHEA-COMP:10034, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:18246, ChEBI:CHEBI:58223, ChEBI:CHEBI:58885; EC=2.4.1.12;
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250};
CC Note=Binds 2 Zn(2+) ions per subunit. {ECO:0000250};
CC -!- PATHWAY: Glycan metabolism; plant cellulose biosynthesis.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. Plant
CC cellulose synthase subfamily. {ECO:0000305}.
CC -!- CAUTION: Lacks the conserved zinc finger domain, which is one of the
CC features of the CESA family. {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP003612; BAD32845.1; -; Genomic_DNA.
DR EMBL; AP003615; BAD35452.1; -; Genomic_DNA.
DR EMBL; AP014962; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_015641259.1; XM_015785773.1.
DR AlphaFoldDB; Q69XK5; -.
DR SMR; Q69XK5; -.
DR STRING; 39947.Q69XK5; -.
DR CAZy; GT2; Glycosyltransferase Family 2.
DR PaxDb; Q69XK5; -.
DR PRIDE; Q69XK5; -.
DR GeneID; 107276400; -.
DR KEGG; osa:107276400; -.
DR eggNOG; ENOG502QQGG; Eukaryota.
DR InParanoid; Q69XK5; -.
DR OrthoDB; 679241at2759; -.
DR UniPathway; UPA00695; -.
DR Proteomes; UP000000763; Chromosome 6.
DR Proteomes; UP000059680; Chromosome 6.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0016760; F:cellulose synthase (UDP-forming) activity; IEA:UniProtKB-EC.
DR GO; GO:0016759; F:cellulose synthase activity; IBA:GO_Central.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0030244; P:cellulose biosynthetic process; IBA:GO_Central.
DR GO; GO:0009833; P:plant-type primary cell wall biogenesis; IBA:GO_Central.
DR Gene3D; 3.90.550.10; -; 1.
DR InterPro; IPR005150; Cellulose_synth.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR Pfam; PF03552; Cellulose_synt; 1.
DR SUPFAM; SSF53448; SSF53448; 1.
PE 5: Uncertain;
KW Cell membrane; Cell wall biogenesis/degradation; Cellulose biosynthesis;
KW Coiled coil; Glycosyltransferase; Membrane; Reference proteome;
KW Transferase; Transmembrane; Transmembrane helix.
FT CHAIN 1..860
FT /note="Putative cellulose synthase A catalytic subunit 11
FT [UDP-forming]"
FT /id="PRO_0000319371"
FT TOPO_DOM 1..43
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 44..64
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 65..72
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 73..93
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 94..626
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 627..647
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 648..657
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 658..678
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 679..701
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 702..722
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 723..757
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 758..778
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 779..789
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 790..810
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 811..823
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 824..844
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 845..860
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REGION 1..36
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 449..468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 223..249
FT /evidence="ECO:0000255"
FT BINDING 334
FT /ligand="substrate"
FT /evidence="ECO:0000255"
FT BINDING 336
FT /ligand="substrate"
FT /evidence="ECO:0000255"
SQ SEQUENCE 860 AA; 93472 MW; 6DFE90A6619D0488 CRC64;
MDGESPEIMP VECPDPEPAS SESGDDHDIP EPLSSRLSVP SGELNLYRAA VALRLVLLAA
FFRYRVTRPV ADAHALWVTS VACELWLAAS WLIAQLPKLS PANRVTYLDR LASRYEKGGE
ASRLAGVDVF VAAADAAREP PLATANTVLS VLAADYPAGG VACYVHDDGA DMLVFESLFE
AAGFARRWIP FCRRHGVEPR APELYFARGV DYLRDRAAPS FVKDRRAMKR EYEEFKVRMN
HLAARARKVP EEGWIMSDGT PWPGNNSRDH PAMIQVLLGH PGDRDVDGGE LPRLFYVSRE
KRPGFRHHGK AGAMNALLRV SAVLTNGAYV LNLDCDHCVN NSSALREAMC FMMDPVAGNR
TCFVQFALRD SGGGDSVFFD IEMKCLDGIQ GPVYVGSGCC FSRKALYGFE PAAAADDGDD
MDTAADWRRM CCFGRGKRMN AMRRSMSAVP LLDSEDDSDE QEEEEAAGRR RRLRAYRAAL
ERHFGQSPAF IASAFEEQGR RRGGDGGSPD ATVAPARSLL KEAIHVVSCA FEERTRWGKE
IGWMYGGGVA TGFRMHARGW SSAYCSPARP AFRRYARASP ADVLAGASRR AVAAMGILLS
RRHSPVWAGR RLGLLQRLGY VARASYPLAS LPLTVYCALP AVCLLTGKST FPSDVSYYDG
VLLILLLFSV AASVALELRW SRVPLRAWWR DEKLWMVTAT SASLAAVFQG ILSACTGIDV
AFSTETAASP PKRPAAGNDD GEEEAALASE ITMRWTNLLV APTSVVVANL AGVVAAVAYG
VDHGYYQSWG ALGAKLALAG WVVAHLQGFL RGLLAPRDRA PPTIAVLWSV VFVSVASLLW
VHAASFSAPT AAPTTEQPIL
