ID   CEST_CITFR              Reviewed;         156 AA.
AC   Q07601;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 53.
DE   RecName: Full=Tir chaperone;
GN   Name=cesT;
OS   Citrobacter freundii.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Citrobacter; Citrobacter freundii complex.
OX   NCBI_TaxID=546;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8500884; DOI=10.1128/iai.61.6.2486-2492.1993;
RA   Schauer D.B., Falkow S.;
RT   "Attaching and effacing locus of a Citrobacter freundii biotype that causes
RT   transmissible murine colonic hyperplasia.";
RL   Infect. Immun. 61:2486-2492(1993).
CC   -!- FUNCTION: Chaperone for the type III secretion of Tir. Probably
CC       stabilizes the protein, prevents inappropriate protein-
CC       proteininteractions and aids in secretion (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CesT/SycH chaperone family. {ECO:0000305}.
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DR   EMBL; L11691; AAA23096.1; -; Genomic_DNA.
DR   PIR; I40704; I40704.
DR   AlphaFoldDB; Q07601; -.
DR   SMR; Q07601; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0030254; P:protein secretion by the type III secretion system; IEA:InterPro.
DR   InterPro; IPR010261; Tir_chaperone.
DR   Pfam; PF05932; CesT; 1.
PE   3: Inferred from homology;
KW   Chaperone; Cytoplasm; Virulence.
FT   CHAIN           1..156
FT                   /note="Tir chaperone"
FT                   /id="PRO_0000216359"
SQ   SEQUENCE   156 AA;  17947 MW;  47C2EED84A103C7B CRC64;
     MSSRSELLLE RFAEKIGIGT ISFNENRLCS FVIDEIYYIS LSDTNDEYMM IYGVCGKFPT
     DNPNFALEIL NANLWFRENG GPYLCYESGA QSLLLALRFP LDDVTPEKLE NEIEVVVKSM
     ENLYLVLHNQ GITLENEHMK IEEISSNDNK HYYAGR