ID   CETZ_PYRHO              Reviewed;         365 AA.
AC   O59060;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 121.
DE   RecName: Full=Tubulin-like protein CetZ {ECO:0000255|HAMAP-Rule:MF_01946};
GN   Name=cetZ {ECO:0000255|HAMAP-Rule:MF_01946}; Synonyms=ftsZ3;
GN   OrderedLocusNames=PH1335;
OS   Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC
OS   100139 / OT-3).
OC   Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC   Pyrococcus.
OX   NCBI_TaxID=70601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3;
RX   PubMed=9679194; DOI=10.1093/dnares/5.2.55;
RA   Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S.,
RA   Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K.,
RA   Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T., Tanaka T.,
RA   Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Yoshizawa T.,
RA   Nakamura Y., Robb F.T., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.;
RT   "Complete sequence and gene organization of the genome of a hyper-
RT   thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
RL   DNA Res. 5:55-76(1998).
CC   -!- FUNCTION: Involved in cell shape control. {ECO:0000255|HAMAP-
CC       Rule:MF_01946}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01946}.
CC   -!- SIMILARITY: Belongs to the CetZ family. {ECO:0000255|HAMAP-
CC       Rule:MF_01946}.
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DR   EMBL; BA000001; BAA30441.1; -; Genomic_DNA.
DR   PIR; A71005; A71005.
DR   RefSeq; WP_010885424.1; NC_000961.1.
DR   AlphaFoldDB; O59060; -.
DR   SMR; O59060; -.
DR   STRING; 70601.3257758; -.
DR   EnsemblBacteria; BAA30441; BAA30441; BAA30441.
DR   GeneID; 1443661; -.
DR   KEGG; pho:PH1335; -.
DR   eggNOG; arCOG02202; Archaea.
DR   OMA; LYQANAG; -.
DR   OrthoDB; 23481at2157; -.
DR   Proteomes; UP000000752; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005874; C:microtubule; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0007017; P:microtubule-based process; IEA:InterPro.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.40.50.1440; -; 1.
DR   HAMAP; MF_01946; CetZ; 1.
DR   InterPro; IPR032907; CetZ.
DR   InterPro; IPR045061; FtsZ/CetZ.
DR   InterPro; IPR036525; Tubulin/FtsZ_GTPase_sf.
DR   InterPro; IPR017975; Tubulin_CS.
DR   InterPro; IPR003008; Tubulin_FtsZ_GTPase.
DR   PANTHER; PTHR30314; PTHR30314; 1.
DR   Pfam; PF00091; Tubulin; 1.
DR   PRINTS; PR00423; CELLDVISFTSZ.
DR   SMART; SM00864; Tubulin; 1.
DR   SUPFAM; SSF52490; SSF52490; 1.
DR   PROSITE; PS00227; TUBULIN; 1.
PE   3: Inferred from homology;
KW   Cell shape; Cytoplasm; GTP-binding; Nucleotide-binding.
FT   CHAIN           1..365
FT                   /note="Tubulin-like protein CetZ"
FT                   /id="PRO_0000114415"
FT   BINDING         10..14
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01946"
FT   BINDING         103..105
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01946"
FT   BINDING         136
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01946"
FT   BINDING         163
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01946"
FT   BINDING         181
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01946"
SQ   SEQUENCE   365 AA;  40118 MW;  DC987E91C761F5B2 CRC64;
     MRAIIIGIGQ CGTKIADIFS LVDFEALAIN TSKSDLEYLK HIPPERRILV GESIVGGKGV
     NANPLLGREA MKRDLPMVMK KISSLVGYED VDIFFLTFGF GGGTGAGGTP VLAEALKEEY
     PDSLVVAIGA LPLKEEGIRP TINAAITIDK LSRIVDSIIA IDNNKLKESD EDISQAYEKI
     NYAIVERIAS LLALIDVPGE QTLDASDLKF VLRAMGSFAT VGYAKADATK IKSLSRLIIR
     SFENEGLYLD VNLESALYGL VAIHGPPEVL KAKEIFDALS ELSQRIRGKQ IFRGFYPDPR
     EREVEVVTLL SGIYESKSIE NIVITAKRYA REFMKAKEEG EMKKRELLKG LPDFEDIYPG
     EVDEG