ID   CF089_DANRE             Reviewed;         309 AA.
AC   A4QNX3;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 56.
DE   RecName: Full=Bombesin receptor-activated protein C6orf89 homolog;
GN   ORFNames=zgc:162255;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exhibits histone deacetylase (HDAC) enhancer properties. May
CC       play a role in progression through the cell cycle (By similarity).
CC       {ECO:0000250|UniProtKB:Q6UWU4}.
CC   -!- SUBUNIT: Homodimer (By similarity). {ECO:0000250|UniProtKB:Q6UWU4}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC       {ECO:0000250|UniProtKB:Q6UWU4}; Single-pass type II membrane protein
CC       {ECO:0000250|UniProtKB:Q6UWU4}. Cytoplasm
CC       {ECO:0000250|UniProtKB:Q6UWU4}.
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DR   EMBL; BC139557; AAI39558.1; -; mRNA.
DR   RefSeq; NP_001082946.1; NM_001089477.1.
DR   AlphaFoldDB; A4QNX3; -.
DR   SMR; A4QNX3; -.
DR   STRING; 7955.ENSDARP00000096095; -.
DR   PaxDb; A4QNX3; -.
DR   GeneID; 100037321; -.
DR   KEGG; dre:100037321; -.
DR   ZFIN; ZDB-GENE-070410-51; zgc:162255.
DR   eggNOG; ENOG502S363; Eukaryota.
DR   InParanoid; A4QNX3; -.
DR   OrthoDB; 1010604at2759; -.
DR   PhylomeDB; A4QNX3; -.
DR   PRO; PR:A4QNX3; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0000139; C:Golgi membrane; ISS:UniProtKB.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030496; C:midbody; ISS:UniProtKB.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; ISS:UniProtKB.
DR   GO; GO:0050673; P:epithelial cell proliferation; ISS:UniProtKB.
DR   GO; GO:0045787; P:positive regulation of cell cycle; ISS:UniProtKB.
DR   GO; GO:1901727; P:positive regulation of histone deacetylase activity; ISS:UniProtKB.
DR   GO; GO:0042060; P:wound healing; ISS:UniProtKB.
DR   InterPro; IPR038757; BRAP.
DR   PANTHER; PTHR35259; PTHR35259; 2.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Golgi apparatus; Membrane; Reference proteome; Signal-anchor;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..309
FT                   /note="Bombesin receptor-activated protein C6orf89 homolog"
FT                   /id="PRO_0000360987"
FT   TOPO_DOM        1..59
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        60..80
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        81..309
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   309 AA;  34716 MW;  C388602D741E0A06 CRC64;
     MGSSLSEPCI YDKLSESIDI LRQSGYRYGM SEREIEKFIK QVLETNEPRR EPPQFPILRA
     TVKFVVAVGV VLMAVLVFTY PQSPVLMGSV SGTTLNNSSP LSHIRLLELP IAEKYNLHGF
     HEWWASSSLQ TMDLNCSACT DVTDILELTD QLRTSAGEHT RTQPLLLKGG AALSLRVSQM
     DQFSSVSQTP ANFTLLWSVS SRPRESVLQW LFPESERCPL LEIWSSTLQR CRLSSRRPQP
     SRVQVLGWMV VADGSPDVRL LPVQRCRKHC RSFSLRLEPG DMVFADSQIW LMELSPSGAQ
     DVQCDSAVL