ID   CF089_PONAB             Reviewed;         347 AA.
AC   Q5R9Q8;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   03-AUG-2022, entry version 58.
DE   RecName: Full=Bombesin receptor-activated protein C6orf89 homolog;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Exhibits histone deacetylase (HDAC) enhancer properties. May
CC       play a role in cell cycle progression and wound repair of bronchial
CC       epithelial cells. {ECO:0000250|UniProtKB:Q6UWU4}.
CC   -!- SUBUNIT: Homodimer (By similarity). Interacts with BRS3 (By
CC       similarity). Interacts (via N-terminus) with SIN3B (By similarity).
CC       {ECO:0000250|UniProtKB:Q6UWU4}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC       {ECO:0000250|UniProtKB:Q6UWU4}; Single-pass type II membrane protein
CC       {ECO:0000250|UniProtKB:Q6UWU4}. Cytoplasm
CC       {ECO:0000250|UniProtKB:Q6UWU4}.
CC   -!- PTM: Glycosylated. {ECO:0000250|UniProtKB:Q6UWU4}.
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DR   EMBL; CR859324; CAH91502.1; -; mRNA.
DR   RefSeq; NP_001125883.1; NM_001132411.1.
DR   RefSeq; XP_009240090.1; XM_009241815.1.
DR   RefSeq; XP_009240091.1; XM_009241816.1.
DR   RefSeq; XP_009240092.1; XM_009241817.1.
DR   AlphaFoldDB; Q5R9Q8; -.
DR   SMR; Q5R9Q8; -.
DR   STRING; 9601.ENSPPYP00000018517; -.
DR   Ensembl; ENSPPYT00000054691; ENSPPYP00000028751; ENSPPYG00000016555.
DR   GeneID; 100172815; -.
DR   KEGG; pon:100172815; -.
DR   CTD; 115583640; -.
DR   eggNOG; ENOG502S363; Eukaryota.
DR   GeneTree; ENSGT00390000014270; -.
DR   HOGENOM; CLU_796829_0_0_1; -.
DR   Proteomes; UP000001595; Chromosome 6.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0000139; C:Golgi membrane; ISS:UniProtKB.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030496; C:midbody; ISS:UniProtKB.
DR   GO; GO:0005886; C:plasma membrane; ISS:UniProtKB.
DR   GO; GO:0050673; P:epithelial cell proliferation; ISS:UniProtKB.
DR   GO; GO:0045787; P:positive regulation of cell cycle; ISS:UniProtKB.
DR   GO; GO:1901727; P:positive regulation of histone deacetylase activity; ISS:UniProtKB.
DR   GO; GO:0042060; P:wound healing; ISS:UniProtKB.
DR   InterPro; IPR038757; BRAP.
DR   PANTHER; PTHR35259; PTHR35259; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Glycoprotein; Golgi apparatus; Membrane; Reference proteome;
KW   Signal-anchor; Transmembrane; Transmembrane helix.
FT   CHAIN           1..347
FT                   /note="Bombesin receptor-activated protein C6orf89 homolog"
FT                   /id="PRO_0000237623"
FT   TOPO_DOM        1..58
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        59..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        80..347
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   347 AA;  39927 MW;  9897B451684191B2 CRC64;
     MDLAANEISI YDKLSETVDL VRQTGHQCGM SEKAIEKFIR QLLEKNEPQR PPPQYPLLIV
     VYKVLATLGL ILLTAYFVIQ PFSPLAPEPV LSGAHTWRSL IHHIRLMSLP IAKKYMSENK
     GVPLHVGDED RPFPDFDPWW TNDCEQNESE PIPANCTGCA QKHLKVMLLE DAPRKFERLH
     PLVIKTGKPL LSEEIQHFLC QYPEATEGFS EGFFAKWWRC FPERWFPFPY PWRRPLNRSQ
     ILRELFPVFT HLPFPKDASL NKCFFLHPEP VVGSKMHKMP DLFIIGSGEA MLQLIPPFQC
     RRHCQSVAMP IEPGDIGYVD TTHWKVYIIA RGVQPLVICD GTAFSEL