ID   CF163_HUMAN             Reviewed;         329 AA.
AC   Q5TEZ5;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 2.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Uncharacterized protein C6orf163;
GN   Name=C6orf163;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=14574404; DOI=10.1038/nature02055;
RA   Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L.,
RA   Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R.,
RA   Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D.,
RA   Andrews T.D., Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J.,
RA   Banerjee R., Barker D.J., Barlow K.F., Bates K., Beare D.M., Beasley H.,
RA   Beasley O., Bird C.P., Blakey S.E., Bray-Allen S., Brook J., Brown A.J.,
RA   Brown J.Y., Burford D.C., Burrill W., Burton J., Carder C., Carter N.P.,
RA   Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V.,
RA   Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J.,
RA   Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E., Ellington A.E.,
RA   Evans K.A., Faulkner L., Francis M.D., Frankish A., Frankland J.,
RA   French L., Garner P., Garnett J., Ghori M.J., Gilby L.M., Gillson C.J.,
RA   Glithero R.J., Grafham D.V., Grant M., Gribble S., Griffiths C.,
RA   Griffiths M.N.D., Hall R., Halls K.S., Hammond S., Harley J.L., Hart E.A.,
RA   Heath P.D., Heathcott R., Holmes S.J., Howden P.J., Howe K.L., Howell G.R.,
RA   Huckle E., Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M.,
RA   Joy A.A., Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K.,
RA   Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R.,
RA   Lloyd D.M., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M.,
RA   Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K., McMurray A.,
RA   Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T., Novik K.L.,
RA   Oliver K., Overton-Larty E.K., Parker A., Patel R., Pearce A.V., Peck A.I.,
RA   Phillimore B.J.C.T., Phillips S., Plumb R.W., Porter K.M., Ramsey Y.,
RA   Ranby S.A., Rice C.M., Ross M.T., Searle S.M., Sehra H.K., Sheridan E.,
RA   Skuce C.D., Smith S., Smith M., Spraggon L., Squares S.L., Steward C.A.,
RA   Sycamore N., Tamlyn-Hall G., Tester J., Theaker A.J., Thomas D.W.,
RA   Thorpe A., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M.,
RA   West A.P., White S.S., Whitehead S.L., Whittaker H., Wild A., Willey D.J.,
RA   Wilmer T.E., Wood J.M., Wray P.W., Wyatt J.C., Young L., Younger R.M.,
RA   Bentley D.R., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Dunham I.,
RA   Rogers J., Beck S.;
RT   "The DNA sequence and analysis of human chromosome 6.";
RL   Nature 425:805-811(2003).
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DR   EMBL; AL096817; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS55042.1; -.
DR   RefSeq; NP_001010868.2; NM_001010868.2.
DR   AlphaFoldDB; Q5TEZ5; -.
DR   SMR; Q5TEZ5; -.
DR   BioGRID; 128504; 1.
DR   STRING; 9606.ENSP00000373575; -.
DR   iPTMnet; Q5TEZ5; -.
DR   PhosphoSitePlus; Q5TEZ5; -.
DR   BioMuta; C6orf163; -.
DR   DMDM; 122063305; -.
DR   EPD; Q5TEZ5; -.
DR   MassIVE; Q5TEZ5; -.
DR   PaxDb; Q5TEZ5; -.
DR   PeptideAtlas; Q5TEZ5; -.
DR   PRIDE; Q5TEZ5; -.
DR   ProteomicsDB; 65068; -.
DR   Antibodypedia; 51525; 65 antibodies from 11 providers.
DR   DNASU; 206412; -.
DR   Ensembl; ENST00000388923.5; ENSP00000373575.3; ENSG00000203872.7.
DR   GeneID; 206412; -.
DR   KEGG; hsa:206412; -.
DR   MANE-Select; ENST00000388923.5; ENSP00000373575.3; NM_001010868.3; NP_001010868.2.
DR   UCSC; uc021zcl.2; human.
DR   CTD; 206412; -.
DR   GeneCards; C6orf163; -.
DR   HGNC; HGNC:21403; C6orf163.
DR   HPA; ENSG00000203872; Tissue enhanced (testis).
DR   neXtProt; NX_Q5TEZ5; -.
DR   OpenTargets; ENSG00000203872; -.
DR   PharmGKB; PA134938121; -.
DR   VEuPathDB; HostDB:ENSG00000203872; -.
DR   eggNOG; ENOG502RDFA; Eukaryota.
DR   GeneTree; ENSGT00390000010837; -.
DR   HOGENOM; CLU_836681_0_0_1; -.
DR   InParanoid; Q5TEZ5; -.
DR   OMA; NYTNFVC; -.
DR   OrthoDB; 1331159at2759; -.
DR   PhylomeDB; Q5TEZ5; -.
DR   TreeFam; TF335705; -.
DR   PathwayCommons; Q5TEZ5; -.
DR   SignaLink; Q5TEZ5; -.
DR   BioGRID-ORCS; 206412; 15 hits in 1045 CRISPR screens.
DR   GenomeRNAi; 206412; -.
DR   Pharos; Q5TEZ5; Tdark.
DR   PRO; PR:Q5TEZ5; -.
DR   Proteomes; UP000005640; Chromosome 6.
DR   RNAct; Q5TEZ5; protein.
DR   Bgee; ENSG00000203872; Expressed in sperm and 100 other tissues.
DR   ExpressionAtlas; Q5TEZ5; baseline and differential.
DR   Genevisible; Q5TEZ5; HS.
DR   InterPro; IPR038927; C6orf163.
DR   PANTHER; PTHR34645; PTHR34645; 1.
PE   4: Predicted;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..329
FT                   /note="Uncharacterized protein C6orf163"
FT                   /id="PRO_0000271361"
FT   COILED          57..120
FT                   /evidence="ECO:0000255"
FT   COILED          225..251
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   329 AA;  38553 MW;  E76946A5C3C768D2 CRC64;
     MIRNSDYKNF VCCAVCNKII PPAPFGKTFK RIHEYKPLKT RFYTHKDILD IGANILKKEE
     QFQEDILREH IAKAEAEVWA QANERQKQAV EKALEEANDR HKIEIQILKE EHQKDLQEVT
     AKTKTEMYQN MDDEMKREHL AAEQRMVHRI QRIMMECHRE KVEAVEKARA EERHIAQEAI
     QAQKSKAVEE IVNTGVTVIK DEKTSVARLM REKEHEMSIL YGIAQRQRQE EVQEVLQEAE
     KTHQATLGNM MDKLANTQGE LLSIAKQLGI MTNWKDFLEE ELQETRMAFQ KYINYTFPKL
     SPGHADFILP ERKKTPSNLV IKENKTTLD