ID   CF300_BOVIN             Reviewed;         267 AA.
AC   Q2HJH8;
DT   06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=Cilia- and flagella-associated protein 300 {ECO:0000305};
GN   Name=CFAP300 {ECO:0000250|UniProtKB:Q9BRQ4};
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Cilium- and flagellum-specific protein that plays a role in
CC       axonemal structure organization and motility. May play a role in outer
CC       and inner dynein arm assembly. {ECO:0000250|UniProtKB:A0CY51}.
CC   -!- SUBUNIT: Interacts with DNAAF2. {ECO:0000250|UniProtKB:Q9BRQ4}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:A0CY51}.
CC       Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:A0CY51}.
CC   -!- SIMILARITY: Belongs to the CFAP300 family. {ECO:0000305}.
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DR   EMBL; BC105371; AAI05372.1; -; mRNA.
DR   RefSeq; NP_001040063.1; NM_001046598.2.
DR   AlphaFoldDB; Q2HJH8; -.
DR   STRING; 9913.ENSBTAP00000020352; -.
DR   PaxDb; Q2HJH8; -.
DR   PRIDE; Q2HJH8; -.
DR   Ensembl; ENSBTAT00000020352; ENSBTAP00000020352; ENSBTAG00000015309.
DR   GeneID; 617430; -.
DR   KEGG; bta:617430; -.
DR   CTD; 85016; -.
DR   VEuPathDB; HostDB:ENSBTAG00000015309; -.
DR   eggNOG; ENOG502QUFH; Eukaryota.
DR   GeneTree; ENSGT00510000047559; -.
DR   OMA; VVPCTQI; -.
DR   OrthoDB; 1089634at2759; -.
DR   Proteomes; UP000009136; Chromosome 15.
DR   Bgee; ENSBTAG00000015309; Expressed in oocyte and 96 other tissues.
DR   ExpressionAtlas; Q2HJH8; baseline.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR   GO; GO:0031514; C:motile cilium; ISS:UniProtKB.
DR   InterPro; IPR029416; CFAP300.
DR   PANTHER; PTHR31078; PTHR31078; 1.
DR   Pfam; PF14926; DUF4498; 1.
PE   2: Evidence at transcript level;
KW   Cell projection; Cytoplasm; Cytoskeleton; Reference proteome.
FT   CHAIN           1..267
FT                   /note="Cilia- and flagella-associated protein 300"
FT                   /id="PRO_0000274275"
SQ   SEQUENCE   267 AA;  30691 MW;  94B9BA266DCF5A5B CRC64;
     MAAGEPGDLG VYSFRFLPQK TFQSLSTPQT TSRLRQWSML GRIEAQAFGF DQTFQAYRKD
     DFVTAFFKDP NVIPNLKLLS ESSGEWLTLG TEVKKIEAIN VPCTQLSMSF FNRLYDEAIV
     RDNGYIVKCL DSFCDPFLIS DELRKVLLVE DSEKYEVFSQ PEREEFLFCL FKHLCLGGAL
     CQYEDVINPY LETTKLIYKD LVSVRKNPQT KKIQITSSIF KVTAYDSVGV CYPSTKSHEQ
     TFSYFIVDPI KRHVHVLYHC YGMGEVS