ID   CF300_XENTR             Reviewed;         267 AA.
AC   Q5I0R4;
DT   06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=Cilia- and flagella-associated protein 300 {ECO:0000305};
GN   Name=cfap300 {ECO:0000250|UniProtKB:Q9BRQ4};
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Cilium- and flagellum-specific protein that plays a role in
CC       axonemal structure organization and motility. May play a role in outer
CC       and inner dynein arm assembly. {ECO:0000250|UniProtKB:A0CY51}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:A0CY51}.
CC       Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:A0CY51}.
CC   -!- SIMILARITY: Belongs to the CFAP300 family. {ECO:0000305}.
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DR   EMBL; BC088061; AAH88061.1; -; mRNA.
DR   RefSeq; NP_001011429.1; NM_001011429.1.
DR   AlphaFoldDB; Q5I0R4; -.
DR   STRING; 8364.ENSXETP00000047995; -.
DR   PaxDb; Q5I0R4; -.
DR   DNASU; 496912; -.
DR   GeneID; 496912; -.
DR   KEGG; xtr:496912; -.
DR   CTD; 85016; -.
DR   Xenbase; XB-GENE-943457; cfap300.
DR   eggNOG; ENOG502QUFH; Eukaryota.
DR   InParanoid; Q5I0R4; -.
DR   OrthoDB; 1089634at2759; -.
DR   Proteomes; UP000008143; Chromosome 2.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000022178; Expressed in testis and 9 other tissues.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR   GO; GO:0031514; C:motile cilium; ISS:UniProtKB.
DR   InterPro; IPR029416; CFAP300.
DR   PANTHER; PTHR31078; PTHR31078; 1.
DR   Pfam; PF14926; DUF4498; 1.
PE   2: Evidence at transcript level;
KW   Cell projection; Cytoplasm; Cytoskeleton; Reference proteome.
FT   CHAIN           1..267
FT                   /note="Cilia- and flagella-associated protein 300"
FT                   /id="PRO_0000274278"
SQ   SEQUENCE   267 AA;  30709 MW;  0B2FB5524D28206A CRC64;
     MSAGSFSTEA AKFSFSPILN KTFGFLTNRD TRELLMKWSM NGRITAQAFR YDECFQPYQK
     NDFVWAFFQD PDVLSHLKIV SENSGQWVTL GTKVKKVDVQ EILCSQLSMS LFDCLYSEGI
     VRESGHICKC LDEYLDDFTI SDELRKVLLL DDCEKHDVFS QSDREQFLFL LFKHLCLGGA
     ICQFEDTIGP YLETTKSIYK DLLSVQKDPE TKQIRIISTV FKVSAYDENG MCYPSGRPHQ
     QTFAYLIVDP LKRHVYVLYH CFGGGAF