ID   CF418_RAT               Reviewed;         210 AA.
AC   Q6AY71;
DT   09-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2004, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Cilia- and flagella-associated protein 418;
GN   Name=Cfap418 {ECO:0000312|RGD:1549749};
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: May be involved in photoreceptor outer segment disk
CC       morphogenesis (By similarity). {ECO:0000250|UniProtKB:Q3UJP5}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q3UJP5}.
CC       Photoreceptor inner segment {ECO:0000250|UniProtKB:Q3UJP5}. Note=In the
CC       retina, located at the base of the primary cilium (By similarity).
CC       Expressed throughout photoreceptors cell body including the basal body,
CC       inner segment and synaptic terminus, but not in the outer segment (By
CC       similarity). {ECO:0000250|UniProtKB:Q3UJP5}.
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DR   EMBL; BC079168; AAH79168.1; -; mRNA.
DR   RefSeq; NP_001007747.1; NM_001007746.1.
DR   RefSeq; XP_017449175.1; XM_017593686.1.
DR   RefSeq; XP_017458448.1; XM_017602959.1.
DR   AlphaFoldDB; Q6AY71; -.
DR   SMR; Q6AY71; -.
DR   STRING; 10116.ENSRNOP00000034206; -.
DR   PaxDb; Q6AY71; -.
DR   PRIDE; Q6AY71; -.
DR   GeneID; 362483; -.
DR   KEGG; rno:362483; -.
DR   UCSC; RGD:1549749; rat.
DR   CTD; 157657; -.
DR   RGD; 1549749; Cfap418.
DR   VEuPathDB; HostDB:ENSRNOG00000026672; -.
DR   eggNOG; ENOG502S1KM; Eukaryota.
DR   HOGENOM; CLU_092833_0_0_1; -.
DR   InParanoid; Q6AY71; -.
DR   OMA; VVQAHGK; -.
DR   OrthoDB; 1589583at2759; -.
DR   PhylomeDB; Q6AY71; -.
DR   TreeFam; TF328851; -.
DR   PRO; PR:Q6AY71; -.
DR   Proteomes; UP000002494; Chromosome 5.
DR   Bgee; ENSRNOG00000026672; Expressed in testis and 19 other tissues.
DR   Genevisible; Q6AY71; RN.
DR   GO; GO:0030054; C:cell junction; IEA:Ensembl.
DR   GO; GO:0097546; C:ciliary base; ISO:RGD.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0001917; C:photoreceptor inner segment; ISS:UniProtKB.
DR   GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR   GO; GO:0008594; P:photoreceptor cell morphogenesis; ISS:UniProtKB.
DR   InterPro; IPR029239; CFAP418.
DR   PANTHER; PTHR33958; PTHR33958; 1.
DR   Pfam; PF14996; RMP; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Reference proteome.
FT   CHAIN           1..210
FT                   /note="Cilia- and flagella-associated protein 418"
FT                   /id="PRO_0000271060"
FT   REGION          24..59
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        44..59
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   210 AA;  23771 MW;  D73D5EFBB0CE73AD CRC64;
     MAKDLDELLD EVETKFCRLD PLRLDLGERP KGGSGGGGTH SGDRNGAQEK DTLRSTETFK
     KEDDLDSLIN EIFEEPNFDK KSFQKFKSKS SSNTSVRAPI QGLSKSCSPV YLSGSAIPCG
     IGTNTSQRAC DRLRCVACDF QIVSYNDYMW DKSCDYLFFR NNMPEFHKLK TKLIEKKGAR
     AYACQCSWRT VEELTDLQAD HELRWVCGKH