ID   CFA20_CAEEL             Reviewed;         203 AA.
AC   Q86D25;
DT   24-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Cilia- and flagella-associated protein 20;
GN   ORFNames=C54C6.6;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: Cilium- and flagellum-specific protein that plays a role in
CC       axonemal structure organization and motility.
CC       {ECO:0000250|UniProtKB:Q6B857}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9Y6A4}.
CC       Cytoplasm, cytoskeleton, microtubule organizing center, centrosome,
CC       centriole {ECO:0000250|UniProtKB:Q9Y6A4}. Cytoplasm, cytoskeleton,
CC       cilium basal body {ECO:0000250|UniProtKB:Q9Y6A4}. Cytoplasm,
CC       cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:Q6B857}.
CC       Note=Microtubule inner protein (MIP) part of the dynein-decorated
CC       doublet microtubules (DMTs) in cilia axoneme.
CC       {ECO:0000250|UniProtKB:Q6B857}.
CC   -!- SIMILARITY: Belongs to the CFAP20 family. {ECO:0000305}.
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DR   EMBL; Z77131; CAD66219.1; -; Genomic_DNA.
DR   RefSeq; NP_871706.1; NM_181977.1.
DR   AlphaFoldDB; Q86D25; -.
DR   SMR; Q86D25; -.
DR   STRING; 6239.C54C6.6; -.
DR   EPD; Q86D25; -.
DR   PaxDb; Q86D25; -.
DR   PeptideAtlas; Q86D25; -.
DR   EnsemblMetazoa; C54C6.6.1; C54C6.6.1; WBGene00008288.
DR   GeneID; 353416; -.
DR   KEGG; cel:CELE_C54C6.6; -.
DR   UCSC; C54C6.6; c. elegans.
DR   CTD; 353416; -.
DR   WormBase; C54C6.6; CE33367; WBGene00008288; -.
DR   eggNOG; KOG3213; Eukaryota.
DR   GeneTree; ENSGT00390000004554; -.
DR   HOGENOM; CLU_060610_1_1_1; -.
DR   InParanoid; Q86D25; -.
DR   OMA; RNGHINK; -.
DR   OrthoDB; 1213295at2759; -.
DR   PhylomeDB; Q86D25; -.
DR   PRO; PR:Q86D25; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   GO; GO:0005879; C:axonemal microtubule; ISS:UniProtKB.
DR   GO; GO:0005814; C:centriole; ISS:UniProtKB.
DR   GO; GO:0036064; C:ciliary basal body; ISS:UniProtKB.
DR   GO; GO:0005929; C:cilium; ISS:UniProtKB.
DR   GO; GO:0031514; C:motile cilium; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0060271; P:cilium assembly; IBA:GO_Central.
DR   GO; GO:2000147; P:positive regulation of cell motility; ISS:UniProtKB.
DR   GO; GO:2000253; P:positive regulation of feeding behavior; ISS:UniProtKB.
DR   GO; GO:0060296; P:regulation of cilium beat frequency involved in ciliary motility; ISS:UniProtKB.
DR   InterPro; IPR040441; CFA20/CFAP20DC.
DR   InterPro; IPR007714; CFA20_dom.
DR   PANTHER; PTHR12458; PTHR12458; 1.
DR   Pfam; PF05018; DUF667; 1.
PE   3: Inferred from homology;
KW   Cell projection; Cilium; Cytoplasm; Cytoskeleton; Microtubule; Nucleus;
KW   Reference proteome.
FT   CHAIN           1..203
FT                   /note="Cilia- and flagella-associated protein 20"
FT                   /id="PRO_0000296406"
SQ   SEQUENCE   203 AA;  23656 MW;  98C577E783B5B390 CRC64;
     MFHNTFQSGL LSVLYSIGSK PLQIWDTQIK NGHVKRITDE EIQSLVLEIM GNNISTAFIS
     CPVDPDKTLG IKLPFFVMVV KNMNKYFSFE VQIIDDKKIK RRFRASNYQS ATRVKPFICT
     MPMRMDEGWN QIQFNLSDFV KRAYGTNYVE TLRIQIHANC RIRRVYFADR LYTEDELPAE
     FKLYLPIRGQ LSTQSPAFAM TSE