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ACDD1_METAC
ID   ACDD1_METAC             Reviewed;         436 AA.
AC   Q8TRZ8;
DT   21-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 98.
DE   RecName: Full=Acetyl-CoA decarbonylase/synthase complex subunit delta 1;
DE            Short=ACDS complex subunit delta 1;
DE   AltName: Full=Corrinoid/iron-sulfur component small subunit 1;
GN   Name=cdhD1; OrderedLocusNames=MA_1012;
OS   Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 /
OS   C2A).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX   NCBI_TaxID=188937;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35395 / DSM 2834 / JCM 12185 / C2A;
RX   PubMed=11932238; DOI=10.1101/gr.223902;
RA   Galagan J.E., Nusbaum C., Roy A., Endrizzi M.G., Macdonald P., FitzHugh W.,
RA   Calvo S., Engels R., Smirnov S., Atnoor D., Brown A., Allen N., Naylor J.,
RA   Stange-Thomann N., DeArellano K., Johnson R., Linton L., McEwan P.,
RA   McKernan K., Talamas J., Tirrell A., Ye W., Zimmer A., Barber R.D.,
RA   Cann I., Graham D.E., Grahame D.A., Guss A.M., Hedderich R.,
RA   Ingram-Smith C., Kuettner H.C., Krzycki J.A., Leigh J.A., Li W., Liu J.,
RA   Mukhopadhyay B., Reeve J.N., Smith K., Springer T.A., Umayam L.A.,
RA   White O., White R.H., de Macario E.C., Ferry J.G., Jarrell K.F., Jing H.,
RA   Macario A.J.L., Paulsen I.T., Pritchett M., Sowers K.R., Swanson R.V.,
RA   Zinder S.H., Lander E., Metcalf W.W., Birren B.;
RT   "The genome of Methanosarcina acetivorans reveals extensive metabolic and
RT   physiological diversity.";
RL   Genome Res. 12:532-542(2002).
CC   -!- FUNCTION: Part of a complex that catalyzes the reversible cleavage of
CC       acetyl-CoA, allowing growth on acetate as sole source of carbon and
CC       energy. Probably maintains the overall quaternary structure of the ACDS
CC       complex (By similarity). {ECO:0000250}.
CC   -!- PATHWAY: One-carbon metabolism; methanogenesis from acetate.
CC   -!- SUBUNIT: Heterodimer of delta and gamma chains. The ACDS complex is
CC       made up of alpha, epsilon, beta, gamma and delta chains with a probable
CC       stoichiometry of (alpha(2)epsilon(2))(4)-beta(8)-(gamma(1)delta(1))(8)
CC       (Potential). {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CdhD family. {ECO:0000305}.
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DR   EMBL; AE010299; AAM04442.1; -; Genomic_DNA.
DR   RefSeq; WP_011021047.1; NC_003552.1.
DR   AlphaFoldDB; Q8TRZ8; -.
DR   SMR; Q8TRZ8; -.
DR   STRING; 188937.MA_1012; -.
DR   EnsemblBacteria; AAM04442; AAM04442; MA_1012.
DR   GeneID; 1472902; -.
DR   KEGG; mac:MA_1012; -.
DR   HOGENOM; CLU_040403_0_0_2; -.
DR   InParanoid; Q8TRZ8; -.
DR   OMA; VMDPTTC; -.
DR   OrthoDB; 72026at2157; -.
DR   PhylomeDB; Q8TRZ8; -.
DR   UniPathway; UPA00642; -.
DR   Proteomes; UP000002487; Chromosome.
DR   GO; GO:0019385; P:methanogenesis, from acetate; IEA:UniProtKB-UniRule.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.20; -; 1.
DR   HAMAP; MF_01135; CdhD; 1.
DR   InterPro; IPR016041; Ac-CoA_synth_d_su_TIM-brl.
DR   InterPro; IPR004486; CO_DH/Ac-CoA_synth_dsu.
DR   InterPro; IPR011005; Dihydropteroate_synth-like.
DR   Pfam; PF03599; CdhD; 1.
DR   SUPFAM; SSF51717; SSF51717; 1.
DR   TIGRFAMs; TIGR00381; cdhD; 1.
PE   3: Inferred from homology;
KW   Methanogenesis; Reference proteome.
FT   CHAIN           1..436
FT                   /note="Acetyl-CoA decarbonylase/synthase complex subunit
FT                   delta 1"
FT                   /id="PRO_0000155110"
SQ   SEQUENCE   436 AA;  47069 MW;  8ABB4103DD0E3ED1 CRC64;
     MAKKMKLSDI TNMFAGMDVE ALEGVTIEGD IEIDLGGLGG GFDPMLAAAL GQESAVLAQH
     FARLAGMFGY PVGIGAPAAP AVSPALAAPK LKDLIPAKFD VANIAEWATE IQEVPIGNTS
     ADGGSRGKRV MLGGEKALPF YFDAPMPNRN QVTIDVFDMR IGLAKAVKEN YDEVMDSPGE
     WAKKNVEKFN ADMITIHLIS TDPLIKDTPA KEAAKTVEEV LQAVDVPIAI GGSGNPQKDP
     EVLARAAEVS EGERCLLASA SLNLDYAAIA EAALKYDHDV LSWTQLDMNA QKELNRKLMK
     QCNVPRDRII MDPTTAALGY GLDYAYTNME RIRLAALMGD DELTFPMSSG TTNAWGARES
     WMVSSPLKED SDWGPREYRG PIWEIVTGLS LAIAGNDLFM MMHPTSVAVL KQITQTLFGM
     IDTEQVDVAN WIGAEV
 
 
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