ID   CFA45_CHLRE             Reviewed;         501 AA.
AC   A8I9E8;
DT   26-NOV-2014, integrated into UniProtKB/Swiss-Prot.
DT   04-DEC-2007, sequence version 1.
DT   25-MAY-2022, entry version 48.
DE   RecName: Full=Cilia- and flagella-associated protein 45 {ECO:0000305};
DE   AltName: Full=Flagellum-associated protein 45 {ECO:0000305};
GN   Name=CFAP45 {ECO:0000305}; Synonyms=FAP45 {ECO:0000312|EMBL:EDP06767.1};
GN   ORFNames=CHLREDRAFT_206096 {ECO:0000312|EMBL:EDP06767.1};
OS   Chlamydomonas reinhardtii (Chlamydomonas smithii).
OC   Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC   CS clade; Chlamydomonadales; Chlamydomonadaceae; Chlamydomonas.
OX   NCBI_TaxID=3055;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CC-503;
RX   PubMed=17932292; DOI=10.1126/science.1143609;
RA   Merchant S.S., Prochnik S.E., Vallon O., Harris E.H., Karpowicz S.J.,
RA   Witman G.B., Terry A., Salamov A., Fritz-Laylin L.K., Marechal-Drouard L.,
RA   Marshall W.F., Qu L.H., Nelson D.R., Sanderfoot A.A., Spalding M.H.,
RA   Kapitonov V.V., Ren Q., Ferris P., Lindquist E., Shapiro H., Lucas S.M.,
RA   Grimwood J., Schmutz J., Cardol P., Cerutti H., Chanfreau G., Chen C.L.,
RA   Cognat V., Croft M.T., Dent R., Dutcher S., Fernandez E., Fukuzawa H.,
RA   Gonzalez-Ballester D., Gonzalez-Halphen D., Hallmann A., Hanikenne M.,
RA   Hippler M., Inwood W., Jabbari K., Kalanon M., Kuras R., Lefebvre P.A.,
RA   Lemaire S.D., Lobanov A.V., Lohr M., Manuell A., Meier I., Mets L.,
RA   Mittag M., Mittelmeier T., Moroney J.V., Moseley J., Napoli C.,
RA   Nedelcu A.M., Niyogi K., Novoselov S.V., Paulsen I.T., Pazour G.J.,
RA   Purton S., Ral J.P., Riano-Pachon D.M., Riekhof W., Rymarquis L.,
RA   Schroda M., Stern D., Umen J., Willows R., Wilson N., Zimmer S.L.,
RA   Allmer J., Balk J., Bisova K., Chen C.J., Elias M., Gendler K., Hauser C.,
RA   Lamb M.R., Ledford H., Long J.C., Minagawa J., Page M.D., Pan J.,
RA   Pootakham W., Roje S., Rose A., Stahlberg E., Terauchi A.M., Yang P.,
RA   Ball S., Bowler C., Dieckmann C.L., Gladyshev V.N., Green P., Jorgensen R.,
RA   Mayfield S., Mueller-Roeber B., Rajamani S., Sayre R.T., Brokstein P.,
RA   Dubchak I., Goodstein D., Hornick L., Huang Y.W., Jhaveri J., Luo Y.,
RA   Martinez D., Ngau W.C., Otillar B., Poliakov A., Porter A., Szajkowski L.,
RA   Werner G., Zhou K., Grigoriev I.V., Rokhsar D.S., Grossman A.R.;
RT   "The Chlamydomonas genome reveals the evolution of key animal and plant
RT   functions.";
RL   Science 318:245-250(2007).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY, AND SUBCELLULAR LOCATION.
RX   PubMed=15998802; DOI=10.1083/jcb.200504008;
RA   Pazour G.J., Agrin N., Leszyk J., Witman G.B.;
RT   "Proteomic analysis of a eukaryotic cilium.";
RL   J. Cell Biol. 170:103-113(2005).
CC   -!- SUBCELLULAR LOCATION: Cell projection, cilium, flagellum
CC       {ECO:0000269|PubMed:15998802}.
CC   -!- SIMILARITY: Belongs to the CFAP45 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DS496114; EDP06767.1; -; Genomic_DNA.
DR   RefSeq; XP_001701792.1; XM_001701740.1.
DR   PDB; 6U42; EM; 3.40 A; 5A/5B/5C/5D=1-501.
DR   PDBsum; 6U42; -.
DR   AlphaFoldDB; A8I9E8; -.
DR   SMR; A8I9E8; -.
DR   STRING; 3055.EDP06767; -.
DR   PaxDb; A8I9E8; -.
DR   PRIDE; A8I9E8; -.
DR   EnsemblPlants; PNW86585; PNW86585; CHLRE_02g092700v5.
DR   GeneID; 5727505; -.
DR   Gramene; PNW86585; PNW86585; CHLRE_02g092700v5.
DR   KEGG; cre:CHLRE_02g092700v5; -.
DR   eggNOG; ENOG502QPRZ; Eukaryota.
DR   HOGENOM; CLU_026959_0_0_1; -.
DR   InParanoid; A8I9E8; -.
DR   OMA; MRENCLP; -.
DR   OrthoDB; 1428717at2759; -.
DR   GO; GO:0031514; C:motile cilium; IEA:UniProtKB-SubCell.
DR   InterPro; IPR033253; CFAP45.
DR   InterPro; IPR043597; TPH_dom.
DR   PANTHER; PTHR15504; PTHR15504; 1.
DR   Pfam; PF13868; TPH; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cell projection; Cilium; Coiled coil; Flagellum.
FT   CHAIN           1..501
FT                   /note="Cilia- and flagella-associated protein 45"
FT                   /id="PRO_0000431301"
FT   COILED          75..114
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   501 AA;  58929 MW;  038297D1310653B1 CRC64;
     MPQTPPRSGG YRSGKQSYVD ESLFGGSKRT GAAQVETLDS LKLTAPTRTI SPKDRDVVTL
     TKGDLTRMLK ASPIMTAEDV AAAKREAEAK REQLQAVSKA RKEKMLKLEE EAKKQAPPTE
     TEILQRQLND ATRSRATHMM LEQKDPVKHM NQMMLYSKCV TIRDAQIEEK KQMLAEEEEE
     QRRLDLMMEI ERVKALEQYE ARERQRVEER RKGAAVLSEQ IKERERERIR QEELRDQERL
     QMLREIERLK EEEMQAQIEK KIQAKQLMEE VAAANSEQIK RKEGMKVREK EEDLRIADYI
     LQKEMREQSL AAEKERIAKE KEMETARLRA MQERAADKQS ELDELRARRY QEAKEREWRQ
     KERAYAERQA SMQQELANAR TAQQASKLKQ KAEMARLEHD EFMRVLDVNR AKEYDELQQT
     VNAMTLNSKY KEELLAQIQA NEERRKRERS HYLEEGARLR EAAEKERQLL LQIKDRKLGE
     LESAGVPGKY RAELEKMKIR S