ID   CFA58_CHLRE             Reviewed;         863 AA.
AC   A8HUA1;
DT   04-MAR-2015, integrated into UniProtKB/Swiss-Prot.
DT   04-DEC-2007, sequence version 1.
DT   25-MAY-2022, entry version 47.
DE   RecName: Full=Cilia- and flagella-associated protein 58 {ECO:0000305};
DE   AltName: Full=Flagellum-associated protein 58 {ECO:0000305};
GN   Name=CFAP58 {ECO:0000250|UniProtKB:Q5T655};
GN   Synonyms=FAP58 {ECO:0000312|EMBL:EDP08857.1};
GN   ORFNames=CHLREDRAFT_206234 {ECO:0000312|EMBL:EDP08857.1};
OS   Chlamydomonas reinhardtii (Chlamydomonas smithii).
OC   Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC   CS clade; Chlamydomonadales; Chlamydomonadaceae; Chlamydomonas.
OX   NCBI_TaxID=3055;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CC-503;
RX   PubMed=17932292; DOI=10.1126/science.1143609;
RA   Merchant S.S., Prochnik S.E., Vallon O., Harris E.H., Karpowicz S.J.,
RA   Witman G.B., Terry A., Salamov A., Fritz-Laylin L.K., Marechal-Drouard L.,
RA   Marshall W.F., Qu L.H., Nelson D.R., Sanderfoot A.A., Spalding M.H.,
RA   Kapitonov V.V., Ren Q., Ferris P., Lindquist E., Shapiro H., Lucas S.M.,
RA   Grimwood J., Schmutz J., Cardol P., Cerutti H., Chanfreau G., Chen C.L.,
RA   Cognat V., Croft M.T., Dent R., Dutcher S., Fernandez E., Fukuzawa H.,
RA   Gonzalez-Ballester D., Gonzalez-Halphen D., Hallmann A., Hanikenne M.,
RA   Hippler M., Inwood W., Jabbari K., Kalanon M., Kuras R., Lefebvre P.A.,
RA   Lemaire S.D., Lobanov A.V., Lohr M., Manuell A., Meier I., Mets L.,
RA   Mittag M., Mittelmeier T., Moroney J.V., Moseley J., Napoli C.,
RA   Nedelcu A.M., Niyogi K., Novoselov S.V., Paulsen I.T., Pazour G.J.,
RA   Purton S., Ral J.P., Riano-Pachon D.M., Riekhof W., Rymarquis L.,
RA   Schroda M., Stern D., Umen J., Willows R., Wilson N., Zimmer S.L.,
RA   Allmer J., Balk J., Bisova K., Chen C.J., Elias M., Gendler K., Hauser C.,
RA   Lamb M.R., Ledford H., Long J.C., Minagawa J., Page M.D., Pan J.,
RA   Pootakham W., Roje S., Rose A., Stahlberg E., Terauchi A.M., Yang P.,
RA   Ball S., Bowler C., Dieckmann C.L., Gladyshev V.N., Green P., Jorgensen R.,
RA   Mayfield S., Mueller-Roeber B., Rajamani S., Sayre R.T., Brokstein P.,
RA   Dubchak I., Goodstein D., Hornick L., Huang Y.W., Jhaveri J., Luo Y.,
RA   Martinez D., Ngau W.C., Otillar B., Poliakov A., Porter A., Szajkowski L.,
RA   Werner G., Zhou K., Grigoriev I.V., Rokhsar D.S., Grossman A.R.;
RT   "The Chlamydomonas genome reveals the evolution of key animal and plant
RT   functions.";
RL   Science 318:245-250(2007).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY, AND SUBCELLULAR LOCATION.
RX   PubMed=15998802; DOI=10.1083/jcb.200504008;
RA   Pazour G.J., Agrin N., Leszyk J., Witman G.B.;
RT   "Proteomic analysis of a eukaryotic cilium.";
RL   J. Cell Biol. 170:103-113(2005).
CC   -!- SUBCELLULAR LOCATION: Cell projection, cilium, flagellum
CC       {ECO:0000269|PubMed:15998802}.
CC   -!- SIMILARITY: Belongs to the CFAP58 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; DS496109; EDP08857.1; -; Genomic_DNA.
DR   RefSeq; XP_001693603.1; XM_001693551.1.
DR   AlphaFoldDB; A8HUA1; -.
DR   SMR; A8HUA1; -.
DR   STRING; 3055.EDP08857; -.
DR   PaxDb; A8HUA1; -.
DR   PRIDE; A8HUA1; -.
DR   eggNOG; ENOG502QPV7; Eukaryota.
DR   HOGENOM; CLU_006364_0_0_1; -.
DR   InParanoid; A8HUA1; -.
DR   OrthoDB; 1077673at2759; -.
DR   GO; GO:0005930; C:axoneme; IDA:GeneDB.
DR   GO; GO:0005737; C:cytoplasm; IDA:GeneDB.
DR   GO; GO:0031514; C:motile cilium; IEA:UniProtKB-SubCell.
DR   GO; GO:0060285; P:cilium-dependent cell motility; IMP:GeneDB.
PE   1: Evidence at protein level;
KW   Cell projection; Cilium; Coiled coil; Flagellum.
FT   CHAIN           1..863
FT                   /note="Cilia- and flagella-associated protein 58"
FT                   /id="PRO_0000432112"
FT   REGION          836..863
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          107..600
FT                   /evidence="ECO:0000255"
FT   COILED          631..815
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   863 AA;  100797 MW;  692D5D5AB05D7F68 CRC64;
     MASDFSTGLH GGHHETLEQY NKVLEELAAD AVMDPFRVEY EKLHRALRKT YESQARLAKK
     CQELNSDISL NASKVQSALK LNEEDRETAV ALKREINKAW KMVDDSTVKE TKAKETAQQL
     KVEIANLSRL VEEGAGLAIG EETALNELLK QKEELARERD AQVEQLMKYR SDLMETQEKL
     RAADAEKLQL DADIQHLRGT INDKKAEAER EIRKKERMEK EMKELRQQLE IRSSEIKSKQ
     LQVTSTEEQV ARLEQMLRDA KFATEKVQKE YNMLNERMQK LHHDLEEQIH TNTQLLTENS
     AKQVELRVKE EEISGIKQEA SRVNKLREQT VKKTKQLEEQ RVEVEKERDV LRAELAALER
     ELEAKQKEVD VEKKKLEELT RERDAENATQ KQIDLVKINE NAKRNLEQEI QGYKMEAQKQ
     SKLIYQLEKE REKYDLEAAE AANKYQQAQS EVKLRVDAIM DLQRRIAEGE SKLKQQQNLY
     EAVRADRNLY SKNLIEAQDE IQEMKRKFKI MQHQIEQLKE EITGKDLYLL KEHFEHQKVI
     NEKEQLRNEL DRSKSNIKEA DSAINAQKVE IDKLNHIINE ADQERRRQKK EYDIVVNERD
     ILGTQLVRRN DELAALYERI KIQQATLQMG QSQYRDRLAE IRQLKVRLAD LKRQLHLLKS
     SVSNIDVLKR EVHQLGRELL QERTKVKALS EELENPLNVH RWRKLEGSDP GTYEMIQKIQ
     TLQKRLISKT EEVVEKDLLI QEKEKLYMEL KNILARQPGP EVAEQLSIYQ ANLREKTKQM
     KAMASELNMY QAQVNEYKYE IERLVRELNE MKQVFFDRRK KEQADRARTM KASMYGPSLL
     DQLPGGSGTG SGGMATGGGV GMS