CFA77_DANRE
ID CFA77_DANRE Reviewed; 240 AA.
AC A2BFC9;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 20-FEB-2007, sequence version 1.
DT 03-AUG-2022, entry version 70.
DE RecName: Full=Cilia- and flagella-associated protein 77 {ECO:0000305};
GN Name=cfap77 {ECO:0000250|UniProtKB:Q6ZQR2};
GN ORFNames=si:ch211-215c18.4 {ECO:0000312|EMBL:CAM14051.1};
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tuebingen;
RX PubMed=23594743; DOI=10.1038/nature12111;
RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT "The zebrafish reference genome sequence and its relationship to the human
RT genome.";
RL Nature 496:498-503(2013).
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium
CC {ECO:0000250|UniProtKB:A8IB22}.
CC -!- SIMILARITY: Belongs to the CFAP77 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BX276128; CAM14051.1; -; Genomic_DNA.
DR RefSeq; NP_001138262.1; NM_001144790.1.
DR RefSeq; XP_009299788.1; XM_009301513.2.
DR AlphaFoldDB; A2BFC9; -.
DR STRING; 7955.ENSDARP00000116312; -.
DR PaxDb; A2BFC9; -.
DR PeptideAtlas; A2BFC9; -.
DR Ensembl; ENSDART00000137400; ENSDARP00000122818; ENSDARG00000068122.
DR Ensembl; ENSDART00000145021; ENSDARP00000116312; ENSDARG00000068122.
DR GeneID; 558957; -.
DR KEGG; dre:558957; -.
DR CTD; 389799; -.
DR ZFIN; ZDB-GENE-060526-106; cfap77.
DR ZFIN; ZDB-GENE-060526-105; si:ch211-215c18.3.
DR eggNOG; ENOG502S0WI; Eukaryota.
DR GeneTree; ENSGT00390000014476; -.
DR HOGENOM; CLU_060116_1_0_1; -.
DR InParanoid; A2BFC9; -.
DR OMA; QQPTCPQ; -.
DR OrthoDB; 1242387at2759; -.
DR PhylomeDB; A2BFC9; -.
DR TreeFam; TF329723; -.
DR PRO; PR:A2BFC9; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 5.
DR Bgee; ENSDARG00000068122; Expressed in testis and 10 other tissues.
DR GO; GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
DR InterPro; IPR029147; CFAP77.
DR PANTHER; PTHR28617; PTHR28617; 1.
DR Pfam; PF14825; DUF4483; 1.
PE 3: Inferred from homology;
KW Cell projection; Cilium; Reference proteome.
FT CHAIN 1..240
FT /note="Cilia- and flagella-associated protein 77"
FT /id="PRO_0000360408"
SQ SEQUENCE 240 AA; 27247 MW; D2E6BDACDED79EB6 CRC64;
MESPRIGVVR DSMLHRPLLI KPTLGKSKSR GLSYPGPEFV FGTATTVQDG GVQEAISNWH
THTMSTTHRA AERDFIALNR EGVKSGLVTA KELHQYRATH DIRRKPLTRE GFRRSAPPRL
SPDDSFFVSN RPSTPISELI EYKYAQRWLE EQQVRDRVLQ AHQHKKAQLG RIQDTRTTLL
RKSQPLPEAP STWKLPRFQK VGAALDTFRD PEARKKAMNA HCSESVSRRG ILGQGTYTVD