ID   ACDD_METKA              Reviewed;         400 AA.
AC   Q8TXF2;
DT   21-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Acetyl-CoA decarbonylase/synthase complex subunit delta {ECO:0000255|HAMAP-Rule:MF_01135};
DE            Short=ACDS complex subunit delta {ECO:0000255|HAMAP-Rule:MF_01135};
DE   AltName: Full=Corrinoid/iron-sulfur component small subunit {ECO:0000255|HAMAP-Rule:MF_01135};
GN   Name=cdhD {ECO:0000255|HAMAP-Rule:MF_01135}; OrderedLocusNames=MK0722;
OS   Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938).
OC   Archaea; Euryarchaeota; Methanopyri; Methanopyrales; Methanopyraceae;
OC   Methanopyrus.
OX   NCBI_TaxID=190192;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AV19 / DSM 6324 / JCM 9639 / NBRC 100938;
RX   PubMed=11930014; DOI=10.1073/pnas.032671499;
RA   Slesarev A.I., Mezhevaya K.V., Makarova K.S., Polushin N.N.,
RA   Shcherbinina O.V., Shakhova V.V., Belova G.I., Aravind L., Natale D.A.,
RA   Rogozin I.B., Tatusov R.L., Wolf Y.I., Stetter K.O., Malykh A.G.,
RA   Koonin E.V., Kozyavkin S.A.;
RT   "The complete genome of hyperthermophile Methanopyrus kandleri AV19 and
RT   monophyly of archaeal methanogens.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:4644-4649(2002).
CC   -!- FUNCTION: Part of a complex that catalyzes the reversible cleavage of
CC       acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains
CC       the overall quaternary structure of the ACDS complex.
CC       {ECO:0000255|HAMAP-Rule:MF_01135}.
CC   -!- SUBUNIT: Heterodimer of delta and gamma chains. The ACDS complex is
CC       made up of alpha, epsilon, beta, gamma and delta chains with a probable
CC       stoichiometry of (alpha(2)epsilon(2))(4)-beta(8)-(gamma(1)delta(1))(8).
CC       {ECO:0000255|HAMAP-Rule:MF_01135}.
CC   -!- SIMILARITY: Belongs to the CdhD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01135}.
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DR   EMBL; AE009439; AAM01936.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8TXF2; -.
DR   SMR; Q8TXF2; -.
DR   STRING; 190192.MK0722; -.
DR   EnsemblBacteria; AAM01936; AAM01936; MK0722.
DR   KEGG; mka:MK0722; -.
DR   PATRIC; fig|190192.8.peg.763; -.
DR   HOGENOM; CLU_040403_0_0_2; -.
DR   OMA; VMDPTTC; -.
DR   Proteomes; UP000001826; Chromosome.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.20; -; 1.
DR   HAMAP; MF_01135; CdhD; 1.
DR   InterPro; IPR016041; Ac-CoA_synth_d_su_TIM-brl.
DR   InterPro; IPR004486; CO_DH/Ac-CoA_synth_dsu.
DR   InterPro; IPR011005; Dihydropteroate_synth-like.
DR   Pfam; PF03599; CdhD; 1.
DR   SUPFAM; SSF51717; SSF51717; 1.
DR   TIGRFAMs; TIGR00381; cdhD; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..400
FT                   /note="Acetyl-CoA decarbonylase/synthase complex subunit
FT                   delta"
FT                   /id="PRO_0000155113"
SQ   SEQUENCE   400 AA;  44543 MW;  83ADA136E30C07CB CRC64;
     MAEDKGVKNM LEHLVKNLLV EDVEEIELRN VTIELDELEL DLKTVAQTLP VEIWERILKP
     EVEEKEREVE VPEYEPPVEE YEGCVAEVQI GATRSDGGSR DRVVVLGGER AYFPFEEPRP
     NPPVVTFDVF DTPDVGIPGP IREELGDVIE DPVDWARTVV KRYGVDIVTV HLVSTSPKLH
     DAPVEEAMET LEDILDAVKV PIIVGGSGDP EKDVEVFVKA AEVCEGERVM LSSINEDMDF
     ERVVEAAKEH GHVVLTFAPV DVNLMKSLNK KVLNRGLSKE DVVMDPTTCA LGYGIEYTID
     VMTRIRLAAL KGDEHLQMPI SSGSTNAWAA REAWMKEESW GPREYRGPLW EAVTATTVAL
     CGADLLMMFH PWAVQVVMEA MEYMAEGRVT GDAYVTDVIA