ID   ACDD_METMA              Reviewed;         436 AA.
AC   Q8PRQ5;
DT   21-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   25-MAY-2022, entry version 110.
DE   RecName: Full=Acetyl-CoA decarbonylase/synthase complex subunit delta {ECO:0000255|HAMAP-Rule:MF_01135};
DE            Short=ACDS complex subunit delta {ECO:0000255|HAMAP-Rule:MF_01135};
DE   AltName: Full=Corrinoid/iron-sulfur component small subunit {ECO:0000255|HAMAP-Rule:MF_01135};
GN   Name=cdhD1 {ECO:0000255|HAMAP-Rule:MF_01135}; OrderedLocusNames=MM_0688;
GN   and
GN   Name=cdhD2 {ECO:0000255|HAMAP-Rule:MF_01135}; OrderedLocusNames=MM_2085;
OS   Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM
OS   11833 / OCM 88) (Methanosarcina frisia).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanosarcina.
OX   NCBI_TaxID=192952;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88;
RX   PubMed=12125824;
RA   Deppenmeier U., Johann A., Hartsch T., Merkl R., Schmitz R.A.,
RA   Martinez-Arias R., Henne A., Wiezer A., Baeumer S., Jacobi C.,
RA   Brueggemann H., Lienard T., Christmann A., Boemecke M., Steckel S.,
RA   Bhattacharyya A., Lykidis A., Overbeek R., Klenk H.-P., Gunsalus R.P.,
RA   Fritz H.-J., Gottschalk G.;
RT   "The genome of Methanosarcina mazei: evidence for lateral gene transfer
RT   between Bacteria and Archaea.";
RL   J. Mol. Microbiol. Biotechnol. 4:453-461(2002).
CC   -!- FUNCTION: Part of a complex that catalyzes the reversible cleavage of
CC       acetyl-CoA, allowing growth on acetate as sole source of carbon and
CC       energy. Probably maintains the overall quaternary structure of the ACDS
CC       complex. {ECO:0000255|HAMAP-Rule:MF_01135}.
CC   -!- PATHWAY: One-carbon metabolism; methanogenesis from acetate.
CC       {ECO:0000255|HAMAP-Rule:MF_01135}.
CC   -!- SUBUNIT: Heterodimer of delta and gamma chains. The ACDS complex is
CC       made up of alpha, epsilon, beta, gamma and delta chains with a probable
CC       stoichiometry of (alpha(2)epsilon(2))(4)-beta(8)-(gamma(1)delta(1))(8).
CC       {ECO:0000255|HAMAP-Rule:MF_01135}.
CC   -!- SIMILARITY: Belongs to the CdhD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01135}.
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DR   EMBL; AE008384; AAM30384.1; -; Genomic_DNA.
DR   EMBL; AE008384; AAM31781.1; -; Genomic_DNA.
DR   RefSeq; WP_011032639.1; NC_003901.1.
DR   AlphaFoldDB; Q8PRQ5; -.
DR   SMR; Q8PRQ5; -.
DR   STRING; 192952.MM_0688; -.
DR   EnsemblBacteria; AAM30384; AAM30384; MM_0688.
DR   EnsemblBacteria; AAM31781; AAM31781; MM_2085.
DR   GeneID; 44088286; -.
DR   GeneID; 66137924; -.
DR   KEGG; mma:MM_0688; -.
DR   KEGG; mma:MM_2085; -.
DR   PATRIC; fig|192952.21.peg.2393; -.
DR   eggNOG; arCOG01980; Archaea.
DR   HOGENOM; CLU_040403_0_0_2; -.
DR   OMA; VMDPTTC; -.
DR   UniPathway; UPA00642; -.
DR   Proteomes; UP000000595; Chromosome.
DR   GO; GO:0019385; P:methanogenesis, from acetate; IEA:UniProtKB-UniRule.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.20; -; 1.
DR   HAMAP; MF_01135; CdhD; 1.
DR   InterPro; IPR016041; Ac-CoA_synth_d_su_TIM-brl.
DR   InterPro; IPR004486; CO_DH/Ac-CoA_synth_dsu.
DR   InterPro; IPR011005; Dihydropteroate_synth-like.
DR   Pfam; PF03599; CdhD; 1.
DR   SUPFAM; SSF51717; SSF51717; 1.
DR   TIGRFAMs; TIGR00381; cdhD; 1.
PE   3: Inferred from homology;
KW   Methanogenesis; Reference proteome.
FT   CHAIN           1..436
FT                   /note="Acetyl-CoA decarbonylase/synthase complex subunit
FT                   delta"
FT                   /id="PRO_0000155114"
SQ   SEQUENCE   436 AA;  46934 MW;  A4BC25CC72B99B3F CRC64;
     MAKKMKLSDI TNMFAGMDVE ALEGVTIEGD IEIDLGGLGG GFDPMLAAAL GQESAVLAQH
     FARIAGMFGY PVGIGAPAAP AISPALAAPK LKDLIPAKFD VANIAEWATQ IQEVPIGNTS
     ADGGSRGKRV LVGGEKALPF FPDAPMPNRN QVTIDVFDMR IGLAKAVKEN YDEVMDSPGE
     WAKKNVEKFN ADMITIHLIS TDPLVKDTPP KEAAKTVEEV LQAVDVPIAI GGSGNPQKDP
     EVLARAAEVA EGERCLLASA SLNLDYAAIA EAALKYDHDV LSWTQLDMNA QKELNRKLMK
     QCNVPRDRII MDPTTAALGY GLDYAYTNME RIRLAALMGD DELTFPMSSG TTNAWGARES
     WMVGSPLKED SDWGPREYRG PIWEIVTGLS LAIAGNDLFM MMHPTSVAVL KQITQTLFGT
     IDTEQVDIAN WIGAEV