ID   CFA97_RAT               Reviewed;         548 AA.
AC   Q66H34;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=Cilia- and flagella-associated protein 97 {ECO:0000312|RGD:1307325};
GN   Name=Cfap97 {ECO:0000312|RGD:1307325};
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [2]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-8; SER-19; SER-160; SER-161
RP   AND SER-259, AND IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE
RP   ANALYSIS].
RX   PubMed=22673903; DOI=10.1038/ncomms1871;
RA   Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C.,
RA   Olsen J.V.;
RT   "Quantitative maps of protein phosphorylation sites across 14 different rat
RT   organs and tissues.";
RL   Nat. Commun. 3:876-876(2012).
CC   -!- SIMILARITY: Belongs to the CFAP97 family. {ECO:0000305}.
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DR   EMBL; BC082052; AAH82052.1; -; mRNA.
DR   RefSeq; NP_001014023.1; NM_001014001.1.
DR   RefSeq; XP_008769484.1; XM_008771262.1.
DR   RefSeq; XP_008769485.1; XM_008771263.1.
DR   RefSeq; XP_008769486.1; XM_008771264.2.
DR   RefSeq; XP_017455608.1; XM_017600119.1.
DR   AlphaFoldDB; Q66H34; -.
DR   SMR; Q66H34; -.
DR   STRING; 10116.ENSRNOP00000042262; -.
DR   iPTMnet; Q66H34; -.
DR   PhosphoSitePlus; Q66H34; -.
DR   PaxDb; Q66H34; -.
DR   PRIDE; Q66H34; -.
DR   Ensembl; ENSRNOT00000045721; ENSRNOP00000042262; ENSRNOG00000032192.
DR   GeneID; 306469; -.
DR   KEGG; rno:306469; -.
DR   CTD; 57587; -.
DR   RGD; 1307325; Cfap97.
DR   eggNOG; ENOG502S0ZF; Eukaryota.
DR   GeneTree; ENSGT00390000010356; -.
DR   HOGENOM; CLU_040301_1_0_1; -.
DR   InParanoid; Q66H34; -.
DR   OMA; KRNACRN; -.
DR   OrthoDB; 947267at2759; -.
DR   PhylomeDB; Q66H34; -.
DR   TreeFam; TF336369; -.
DR   PRO; PR:Q66H34; -.
DR   Proteomes; UP000002494; Chromosome 16.
DR   Bgee; ENSRNOG00000032192; Expressed in testis and 20 other tissues.
DR   Genevisible; Q66H34; RN.
DR   GO; GO:0007283; P:spermatogenesis; IBA:GO_Central.
DR   InterPro; IPR038791; Cfap97/Hemingway.
DR   InterPro; IPR029488; Hmw/CFAP97.
DR   PANTHER; PTHR23035; PTHR23035; 1.
DR   Pfam; PF13879; Hmw_CFAP97; 1.
PE   1: Evidence at protein level;
KW   Coiled coil; Phosphoprotein; Reference proteome.
FT   CHAIN           1..548
FT                   /note="Cilia- and flagella-associated protein 97"
FT                   /evidence="ECO:0000305"
FT                   /id="PRO_0000309227"
FT   REGION          85..297
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          407..431
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          497..548
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          383..460
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        88..108
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        109..126
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        145..170
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        173..241
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        260..292
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        499..524
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         8
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
FT   MOD_RES         19
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
FT   MOD_RES         155
FT                   /note="Phosphothreonine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9P2B7"
FT   MOD_RES         160
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
FT   MOD_RES         161
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
FT   MOD_RES         235
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q9P2B7"
FT   MOD_RES         259
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
SQ   SEQUENCE   548 AA;  61743 MW;  0E89BCE48AC16F38 CRC64;
     MDRFGDISEG EVDHSFFDSD FEDTKKCESN SIFDKQNDDD FKEGINKDIK NLNLKFGVQN
     DNLKEKIDND TENVNVKLGI QTKENYLTQK GNERKPKFPS KEQHVENDPI QTRSPSLLTS
     SRSKKLCDTT KGNKLHLPVP NRIPKIVKGE DDYYTDGEES SDDGKKYHVR SKSAKPSSNL
     KKNNTSKKYS KASSSSLSSS SSRSSSDCSD IGSDMQNKPD SGSSGKRVSS VTPSSPKQKC
     KSGRKSSAKQ KAGDYNAESE DNVTDVTPAS TPDSSPAQPF ELSQSQNQKV KVKRQENVSR
     DVYEDVEALK NDSRCLKSAK RKEKHGQNFA PKSSVLDANL DRRSKQKVLH DTMDLNHLLK
     AFLQLDKKGP QKHHFEQPSI IPRKNYSFTR EEVRQIDREN QRLLKELSRQ AEKPGNKSTI
     PGRSLGHPPK LYHSALNRQR EQQRIERENM ALLKRLEAVK PTVGMKRSEQ LMDYHRNISY
     LNPSPSVRRV RSTLGHYSPL RGASRTSSAT SGLSCKTDRS VLDTSSGFLL RPKPPNIQCS
     NSKVLRSH