ID   CFA99_CHLRE             Reviewed;         795 AA.
AC   A8IUG5;
DT   26-NOV-2014, integrated into UniProtKB/Swiss-Prot.
DT   04-DEC-2007, sequence version 1.
DT   03-AUG-2022, entry version 52.
DE   RecName: Full=Cilia- and flagella-associated protein 99 {ECO:0000305};
GN   Name=CFAP99 {ECO:0000305}; Synonyms=FAP99 {ECO:0000312|EMBL:EDP03844.1};
GN   ORFNames=CHLREDRAFT_190721 {ECO:0000312|EMBL:EDP03844.1};
OS   Chlamydomonas reinhardtii (Chlamydomonas smithii).
OC   Eukaryota; Viridiplantae; Chlorophyta; core chlorophytes; Chlorophyceae;
OC   CS clade; Chlamydomonadales; Chlamydomonadaceae; Chlamydomonas.
OX   NCBI_TaxID=3055;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CC-503;
RX   PubMed=17932292; DOI=10.1126/science.1143609;
RA   Merchant S.S., Prochnik S.E., Vallon O., Harris E.H., Karpowicz S.J.,
RA   Witman G.B., Terry A., Salamov A., Fritz-Laylin L.K., Marechal-Drouard L.,
RA   Marshall W.F., Qu L.H., Nelson D.R., Sanderfoot A.A., Spalding M.H.,
RA   Kapitonov V.V., Ren Q., Ferris P., Lindquist E., Shapiro H., Lucas S.M.,
RA   Grimwood J., Schmutz J., Cardol P., Cerutti H., Chanfreau G., Chen C.L.,
RA   Cognat V., Croft M.T., Dent R., Dutcher S., Fernandez E., Fukuzawa H.,
RA   Gonzalez-Ballester D., Gonzalez-Halphen D., Hallmann A., Hanikenne M.,
RA   Hippler M., Inwood W., Jabbari K., Kalanon M., Kuras R., Lefebvre P.A.,
RA   Lemaire S.D., Lobanov A.V., Lohr M., Manuell A., Meier I., Mets L.,
RA   Mittag M., Mittelmeier T., Moroney J.V., Moseley J., Napoli C.,
RA   Nedelcu A.M., Niyogi K., Novoselov S.V., Paulsen I.T., Pazour G.J.,
RA   Purton S., Ral J.P., Riano-Pachon D.M., Riekhof W., Rymarquis L.,
RA   Schroda M., Stern D., Umen J., Willows R., Wilson N., Zimmer S.L.,
RA   Allmer J., Balk J., Bisova K., Chen C.J., Elias M., Gendler K., Hauser C.,
RA   Lamb M.R., Ledford H., Long J.C., Minagawa J., Page M.D., Pan J.,
RA   Pootakham W., Roje S., Rose A., Stahlberg E., Terauchi A.M., Yang P.,
RA   Ball S., Bowler C., Dieckmann C.L., Gladyshev V.N., Green P., Jorgensen R.,
RA   Mayfield S., Mueller-Roeber B., Rajamani S., Sayre R.T., Brokstein P.,
RA   Dubchak I., Goodstein D., Hornick L., Huang Y.W., Jhaveri J., Luo Y.,
RA   Martinez D., Ngau W.C., Otillar B., Poliakov A., Porter A., Szajkowski L.,
RA   Werner G., Zhou K., Grigoriev I.V., Rokhsar D.S., Grossman A.R.;
RT   "The Chlamydomonas genome reveals the evolution of key animal and plant
RT   functions.";
RL   Science 318:245-250(2007).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY, AND SUBCELLULAR LOCATION.
RX   PubMed=15998802; DOI=10.1083/jcb.200504008;
RA   Pazour G.J., Agrin N., Leszyk J., Witman G.B.;
RT   "Proteomic analysis of a eukaryotic cilium.";
RL   J. Cell Biol. 170:103-113(2005).
CC   -!- SUBCELLULAR LOCATION: Cell projection, cilium, flagellum
CC       {ECO:0000269|PubMed:15998802}.
CC   -!- SIMILARITY: Belongs to the CFAP99 family. {ECO:0000305}.
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DR   EMBL; DS496124; EDP03844.1; -; Genomic_DNA.
DR   RefSeq; XP_001692825.1; XM_001692773.1.
DR   PDB; 7SQC; EM; 3.80 A; B0/B1/B2=1-795.
DR   PDBsum; 7SQC; -.
DR   AlphaFoldDB; A8IUG5; -.
DR   STRING; 3055.EDP03844; -.
DR   PaxDb; A8IUG5; -.
DR   EnsemblPlants; PNW73238; PNW73238; CHLRE_14g624400v5.
DR   GeneID; 5718407; -.
DR   Gramene; PNW73238; PNW73238; CHLRE_14g624400v5.
DR   KEGG; cre:CHLRE_14g624400v5; -.
DR   eggNOG; ENOG502QTX0; Eukaryota.
DR   HOGENOM; CLU_013681_0_0_1; -.
DR   InParanoid; A8IUG5; -.
DR   OMA; QLDKFKP; -.
DR   OrthoDB; 900058at2759; -.
DR   GO; GO:0031514; C:motile cilium; IEA:UniProtKB-SubCell.
DR   InterPro; IPR039341; CFAP99.
DR   PANTHER; PTHR34649; PTHR34649; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cell projection; Cilium; Coiled coil; Flagellum.
FT   CHAIN           1..795
FT                   /note="Cilia- and flagella-associated protein 99"
FT                   /id="PRO_0000431073"
FT   REGION          1..37
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          215..273
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          754..778
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          353..508
FT                   /evidence="ECO:0000255"
FT   COILED          542..586
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..35
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        239..263
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        754..775
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   795 AA;  90189 MW;  A3B7B703B3ED53E6 CRC64;
     MESRPGSASS YHSHAAGNTQ SRPGSATSVE SSNRLSGKPL GAEKLMAACE KIYKSFNPAQ
     VTLDTHVDNC IGQLSVHNSF DDSFIRQVVY GTVRYRRLLG ALMDSFYHYN GGAASREDVD
     MYKLYSYLTI FRLEELNFSN FQRLVDAMTP QKMYVLLKYM FNPQYMREVV REDWLKLYDK
     EFVDEIIDRL LSWKSESKEM LGRLEYKVTL SRKEDDEKET LGTGYAAARS TTVPQPFNLT
     QPKPRPLPVE DPPPPPIRAK PAPRPREGPT KEEVALAAAR EANRAAAERK AAKAAPFKLR
     VLERPTNIDK IREELEAERT RELTFKGIRA APPPPVPNAQ VRLNAAAILR EDALYRRKQQ
     EEADALKRYE AELRDASSFK AWQNAMLEQD EAARAASVER RRQEMAAAQE NAIRARMAAQ
     EANAELARAA KEEAKRIEED LKRDREEQAR LNALRRDAVV EARQNVQAAV EKMSQERRLA
     AEEERRKQQE DARARAEVAA REMAERRDII LQLKALEKVP KQRVKEFDPT ETGPDHGLLE
     TMSLVELRER LNVAKRRQRE EEERQRAEIL RQKQERESAL LEKAANIQRV RRVAAAQAAQ
     RRATSAETIQ RKNTEVSKAR EADVLQLADK LDAKRAALAA ERARLAAEQK RTRFEQMQAA
     AGAAVVEETK FRELRAGAQR EAKTRQENAL ASATVYEATK ARQQNVRLKN VRQELKAKDD
     FMRAYDEKLA ALRGQAGAES AADLARRTQM AQTQRAAEAT VRNRTTTTAY RPYEGGSTSM
     QARLAALGQG MELED