ID   CFAA_ECOLX              Reviewed;         206 AA.
AC   P25732;
DT   01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1992, sequence version 1.
DT   25-MAY-2022, entry version 50.
DE   RecName: Full=CFA/I fimbrial subunit A;
DE   AltName: Full=Colonization factor antigen I subunit A;
DE   Flags: Precursor;
GN   Name=cfaA;
OS   Escherichia coli.
OG   Plasmid NTP513.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ETEC;
RX   PubMed=2569152; DOI=10.1016/0882-4010(89)90103-4;
RA   Hamers A.M., Pel H.J., Willshaw G.A., Kusters J.G., van der Zeijst B.A.M.,
RA   Gaastra W.;
RT   "The nucleotide sequence of the first two genes of the CFA/I fimbrial
RT   operon of human enterotoxigenic Escherichia coli.";
RL   Microb. Pathog. 6:297-309(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1352712; DOI=10.3109/10425179209020811;
RA   Jordi B.J.A.M., Willshaw G.A., van der Zeijst B.A.M., Gaastra W.;
RT   "The complete nucleotide sequence of region 1 of the CFA/I fimbrial operon
RT   of human enterotoxigenic Escherichia coli.";
RL   DNA Seq. 2:257-263(1992).
CC   -!- FUNCTION: Might function as a shuttle protein in the transport of
CC       fimbria through the periplasmic space or might function as an adhesin.
CC   -!- SUBCELLULAR LOCATION: Fimbrium {ECO:0000305}.
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DR   EMBL; M55661; AAC41414.1; ALT_SEQ; Genomic_DNA.
DR   PIR; A56617; A56617.
DR   AlphaFoldDB; P25732; -.
DR   SMR; P25732; -.
DR   GO; GO:0009289; C:pilus; IEA:UniProtKB-SubCell.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR013783; Ig-like_fold.
PE   3: Inferred from homology;
KW   Fimbrium; Plasmid; Signal.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..206
FT                   /note="CFA/I fimbrial subunit A"
FT                   /id="PRO_0000009247"
SQ   SEQUENCE   206 AA;  23516 MW;  930161A2FEA90CF1 CRC64;
     MHKLFYLLSL LMAPFVANAN FMIYPISKDL KNGNSELVRV YSKSKEIQYI KIYTKKIINP
     GTTEEYKVDI PNWDGGLVVT PQKVILPAGA SKSIRLTQFK IPKKEEVYRV YFEAVKPDSK
     ENVIDNKKLT TELSVNIIYA ALIRSLPSEQ NISLNISRNA KKNIIIYNNG NVRAGVKDIY
     FCKSSNIDDN CVKKAYNKNI YPEKVI