ID   ACDD_METTH              Reviewed;         389 AA.
AC   O27747;
DT   21-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=Acetyl-CoA decarbonylase/synthase complex subunit delta {ECO:0000255|HAMAP-Rule:MF_01135};
DE            Short=ACDS complex subunit delta {ECO:0000255|HAMAP-Rule:MF_01135};
DE   AltName: Full=Corrinoid/iron-sulfur component small subunit {ECO:0000255|HAMAP-Rule:MF_01135};
GN   Name=cdhD {ECO:0000255|HAMAP-Rule:MF_01135}; OrderedLocusNames=MTH_1712;
OS   Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM
OS   10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX   NCBI_TaxID=187420;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H;
RX   PubMed=9371463; DOI=10.1128/jb.179.22.7135-7155.1997;
RA   Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J.,
RA   Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D.,
RA   Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R.,
RA   Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D.,
RA   Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A.,
RA   Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J.,
RA   Reeve J.N.;
RT   "Complete genome sequence of Methanobacterium thermoautotrophicum deltaH:
RT   functional analysis and comparative genomics.";
RL   J. Bacteriol. 179:7135-7155(1997).
CC   -!- FUNCTION: Part of a complex that catalyzes the reversible cleavage of
CC       acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains
CC       the overall quaternary structure of the ACDS complex.
CC       {ECO:0000255|HAMAP-Rule:MF_01135}.
CC   -!- SUBUNIT: Heterodimer of delta and gamma chains. The ACDS complex is
CC       made up of alpha, epsilon, beta, gamma and delta chains with a probable
CC       stoichiometry of (alpha(2)epsilon(2))(4)-beta(8)-(gamma(1)delta(1))(8).
CC       {ECO:0000255|HAMAP-Rule:MF_01135}.
CC   -!- SIMILARITY: Belongs to the CdhD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01135}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE000666; AAB86184.1; -; Genomic_DNA.
DR   PIR; B69096; B69096.
DR   AlphaFoldDB; O27747; -.
DR   SMR; O27747; -.
DR   STRING; 187420.MTH_1712; -.
DR   EnsemblBacteria; AAB86184; AAB86184; MTH_1712.
DR   KEGG; mth:MTH_1712; -.
DR   PATRIC; fig|187420.15.peg.1673; -.
DR   HOGENOM; CLU_040403_0_0_2; -.
DR   OMA; VMDPTTC; -.
DR   Proteomes; UP000005223; Chromosome.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.20; -; 1.
DR   HAMAP; MF_01135; CdhD; 1.
DR   InterPro; IPR016041; Ac-CoA_synth_d_su_TIM-brl.
DR   InterPro; IPR004486; CO_DH/Ac-CoA_synth_dsu.
DR   InterPro; IPR011005; Dihydropteroate_synth-like.
DR   Pfam; PF03599; CdhD; 1.
DR   SUPFAM; SSF51717; SSF51717; 1.
DR   TIGRFAMs; TIGR00381; cdhD; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..389
FT                   /note="Acetyl-CoA decarbonylase/synthase complex subunit
FT                   delta"
FT                   /id="PRO_0000155117"
SQ   SEQUENCE   389 AA;  43785 MW;  AC75FEE22B024591 CRC64;
     MLMDKLTELL KLLQNTESIE INEFRMDVEE LELYLMPAVQ QAIQKTVEVR EAVEALPAEE
     FNPPIRSYPG EVAQVKLGEG TRKSVYLGGQ KALYRFEEPQ PNPPVVTFDV FDIPMPGLPR
     PIREHFSDVM EDPGDWARKA VKEYGANMVT IHLIGTGPKV MDKSPREAAK DIEEVLQAVD
     VPLVIGGSGD PEKDPLVLEK AAEAAEGERC LLASANLDLD YRKVARAALD HNHAVLSWAI
     TDVNMQKTLN RYLLKEGLKR EDIVMDPTTC ALGYGIEFSI DVITRTRLAA LKGDSDLQMP
     MSSGTTNAWG SREAWMKKDE WGPTDYRGPL WEIVTGLTMM LSGVDIFMML HPTSVRLLRE
     IGETFTREYM TAETPDLREW ITELDYQEV