CFDP1_CHICK
ID CFDP1_CHICK Reviewed; 290 AA.
AC Q75QI0; Q8JIM2;
DT 22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 69.
DE RecName: Full=Craniofacial development protein 1;
DE AltName: Full=Bucentaur;
GN Name=CFDP1; Synonyms=BCNT;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Brain;
RX PubMed=12832649; DOI=10.1093/molbev/msg168;
RA Iwashita S., Osada N., Itoh T., Sezaki M., Oshima K., Hashimoto E.,
RA Kitagawa-Arita Y., Takahashi I., Masui T., Hashimoto K., Makalowski W.;
RT "A transposable element-mediated gene divergence that directly produces a
RT novel type bovine Bcnt protein including the endonuclease domain of RTE-
RT 1.";
RL Mol. Biol. Evol. 20:1556-1563(2003).
CC -!- FUNCTION: May play a role during embryogenesis. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Chromosome, centromere, kinetochore
CC {ECO:0000250|UniProtKB:Q9UEE9}.
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DR EMBL; AB080800; BAC11905.1; -; mRNA.
DR EMBL; AB162146; BAD18889.1; -; mRNA.
DR RefSeq; NP_001001189.1; NM_001001189.1.
DR AlphaFoldDB; Q75QI0; -.
DR SMR; Q75QI0; -.
DR STRING; 9031.ENSGALP00000004488; -.
DR PaxDb; Q75QI0; -.
DR GeneID; 374073; -.
DR KEGG; gga:374073; -.
DR CTD; 10428; -.
DR VEuPathDB; HostDB:geneid_374073; -.
DR eggNOG; KOG4776; Eukaryota.
DR InParanoid; Q75QI0; -.
DR OrthoDB; 1372508at2759; -.
DR PhylomeDB; Q75QI0; -.
DR PRO; PR:Q75QI0; -.
DR Proteomes; UP000000539; Unplaced.
DR GO; GO:0000776; C:kinetochore; IEA:UniProtKB-KW.
DR InterPro; IPR011421; BCNT-C.
DR InterPro; IPR027124; Swc5/CFDP1/2.
DR PANTHER; PTHR23227; PTHR23227; 1.
DR Pfam; PF07572; BCNT; 1.
DR PROSITE; PS51279; BCNT_C; 1.
PE 2: Evidence at transcript level;
KW Centromere; Chromosome; Developmental protein; Kinetochore;
KW Reference proteome.
FT CHAIN 1..290
FT /note="Craniofacial development protein 1"
FT /id="PRO_0000212500"
FT DOMAIN 209..290
FT /note="BCNT-C"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00610"
FT REGION 1..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 159..208
FT /note="Hydrophilic"
FT REGION 175..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..39
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 79..95
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 96..110
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 135..159
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 175..190
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 191..212
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 290 AA; 32780 MW; FEBD645590A45487 CRC64;
MSGCEEEAGD GYSSAEDEDY VPSGAEYSEE DESELLREEE EEAAGPRPTR SRNSPRQATR
RKKKKRRGLV LEVDEKEEGK AQENEDEEDD LKQSEKDREE EEKKKEDALW ASFLSDVGQK
PKAAATQATH ADKAGEVKSV NKLQGKPKES EKPKDSGRVT ITKVFDFAGE EVRVTKEVDS
SSKEAKSFLK QQEKWQSSAP GSLPTVSGVK RPSGISSLLG KIGSKKQKMS TLEKSKLDWE
NFKEEEGIVE ELAIHNRGKD GYIERKAFLE RVDHRQFEIE RDIRLSRMKP
