ID   ACDE_METJA              Reviewed;         146 AA.
AC   P81332;
DT   21-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Acetyl-CoA decarbonylase/synthase complex subunit epsilon {ECO:0000255|HAMAP-Rule:MF_01134};
DE            Short=ACDS complex subunit epsilon {ECO:0000255|HAMAP-Rule:MF_01134};
DE   AltName: Full=ACDS complex carbon monoxide dehydrogenase subunit epsilon {ECO:0000255|HAMAP-Rule:MF_01134};
DE            Short=ACDS CODH subunit epsilon {ECO:0000255|HAMAP-Rule:MF_01134};
GN   Name=cdhB {ECO:0000255|HAMAP-Rule:MF_01134}; OrderedLocusNames=MJ0154;
OS   Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM
OS   10045 / NBRC 100440) (Methanococcus jannaschii).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanocaldococcaceae; Methanocaldococcus.
OX   NCBI_TaxID=243232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440;
RX   PubMed=8688087; DOI=10.1126/science.273.5278.1058;
RA   Bult C.J., White O., Olsen G.J., Zhou L., Fleischmann R.D., Sutton G.G.,
RA   Blake J.A., FitzGerald L.M., Clayton R.A., Gocayne J.D., Kerlavage A.R.,
RA   Dougherty B.A., Tomb J.-F., Adams M.D., Reich C.I., Overbeek R.,
RA   Kirkness E.F., Weinstock K.G., Merrick J.M., Glodek A., Scott J.L.,
RA   Geoghagen N.S.M., Weidman J.F., Fuhrmann J.L., Nguyen D., Utterback T.R.,
RA   Kelley J.M., Peterson J.D., Sadow P.W., Hanna M.C., Cotton M.D.,
RA   Roberts K.M., Hurst M.A., Kaine B.P., Borodovsky M., Klenk H.-P.,
RA   Fraser C.M., Smith H.O., Woese C.R., Venter J.C.;
RT   "Complete genome sequence of the methanogenic archaeon, Methanococcus
RT   jannaschii.";
RL   Science 273:1058-1073(1996).
CC   -!- FUNCTION: Part of a complex that catalyzes the reversible cleavage of
CC       acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon
CC       subcomponent functions as a carbon monoxide dehydrogenase. The precise
CC       role of the epsilon subunit is unclear; it may have a stabilizing role
CC       within the alpha(2)epsilon(2) component and/or be involved in electron
CC       transfer to FAD during a potential FAD-mediated CO oxidation.
CC       {ECO:0000255|HAMAP-Rule:MF_01134}.
CC   -!- SUBUNIT: Heterotetramer of two alpha and two epsilon subunits. The ACDS
CC       complex is made up of alpha, epsilon, beta, gamma and delta subunits
CC       with a probable stoichiometry of (alpha(2)epsilon(2))(4)-beta(8)-
CC       (gamma(1)delta(1))(8). {ECO:0000255|HAMAP-Rule:MF_01134}.
CC   -!- SIMILARITY: Belongs to the CdhB family. {ECO:0000255|HAMAP-
CC       Rule:MF_01134}.
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DR   EMBL; L77117; AAB98136.1; -; Genomic_DNA.
DR   RefSeq; WP_010869649.1; NC_000909.1.
DR   AlphaFoldDB; P81332; -.
DR   SMR; P81332; -.
DR   STRING; 243232.MJ_0154; -.
DR   EnsemblBacteria; AAB98136; AAB98136; MJ_0154.
DR   GeneID; 1450998; -.
DR   KEGG; mja:MJ_0154; -.
DR   eggNOG; arCOG04408; Archaea.
DR   HOGENOM; CLU_1773184_0_0_2; -.
DR   InParanoid; P81332; -.
DR   OMA; ITYYYLA; -.
DR   OrthoDB; 109783at2157; -.
DR   Proteomes; UP000000805; Chromosome.
DR   GO; GO:0019385; P:methanogenesis, from acetate; IEA:InterPro.
DR   HAMAP; MF_01134; CdhB; 1.
DR   InterPro; IPR003704; CO_DH_CoA_synth.
DR   InterPro; IPR029035; DHS-like_NAD/FAD-binding_dom.
DR   Pfam; PF02552; CO_dh; 1.
DR   PIRSF; PIRSF006035; CO_dh_b_ACDS_e; 1.
DR   SUPFAM; SSF52467; SSF52467; 1.
DR   TIGRFAMs; TIGR00315; cdhB; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..146
FT                   /note="Acetyl-CoA decarbonylase/synthase complex subunit
FT                   epsilon"
FT                   /id="PRO_0000155090"
SQ   SEQUENCE   146 AA;  16858 MW;  EFF8B65DDF4518D6 CRC64;
     MDERFIAYIP TAGSNVAHAE ITSPTLVKMM IRRAKKPILI LGENLEENEK ELISKLIEKF
     NLKTIKTPEE MNLMAIMKYL ASSDYDLALF TGITYYYLAQ AATHLKQFSN VVTISIDKYY
     QPNTLYSFPN LSKEEYLDYL RKLLEG