CFL2_ARATH
ID CFL2_ARATH Reviewed; 176 AA.
AC Q9C7E6;
DT 03-AUG-2022, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 129.
DE RecName: Full=Protein CURLY FLAG LEAF 2 {ECO:0000303|PubMed:21954461};
DE Short=AtCFL2 {ECO:0000303|PubMed:21954461};
GN Name=CFL2 {ECO:0000303|PubMed:21954461};
GN OrderedLocusNames=At1g28070 {ECO:0000312|Araport:AT1G28070};
GN ORFNames=F13K9.17 {ECO:0000312|EMBL:AAG51495.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Kim C.J., Chen H., Cheuk R.F., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY.
RC STRAIN=cv. Columbia;
RX PubMed=21954461; DOI=10.1105/tpc.111.088625;
RA Wu R., Li S., He S., Wassmann F., Yu C., Qin G., Schreiber L., Qu L.-J.,
RA Gu H.;
RT "CFL1, a WW domain protein, regulates cuticle development by modulating the
RT function of HDG1, a class IV homeodomain transcription factor, in rice and
RT Arabidopsis.";
RL Plant Cell 23:3392-3411(2011).
CC -!- FUNCTION: May regulate negatively the cuticle development by
CC interacting with the HD-ZIP IV transcription factor HDG1.
CC {ECO:0000250|UniProtKB:Q5HZ54}.
CC -!- SUBUNIT: May interact with BHLH122/CFLAP1 and BHLH80/CFLAP2.
CC {ECO:0000250|UniProtKB:Q5HZ54}.
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DR EMBL; AC069471; AAG51495.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE30908.1; -; Genomic_DNA.
DR EMBL; BT011669; AAS47675.1; -; mRNA.
DR EMBL; AK220610; BAD94977.1; -; mRNA.
DR PIR; D86406; D86406.
DR RefSeq; NP_174128.1; NM_102572.3.
DR SMR; Q9C7E6; -.
DR PRIDE; Q9C7E6; -.
DR EnsemblPlants; AT1G28070.1; AT1G28070.1; AT1G28070.
DR GeneID; 839700; -.
DR Gramene; AT1G28070.1; AT1G28070.1; AT1G28070.
DR KEGG; ath:AT1G28070; -.
DR Araport; AT1G28070; -.
DR TAIR; locus:2010534; AT1G28070.
DR eggNOG; ENOG502RXWN; Eukaryota.
DR HOGENOM; CLU_070197_2_0_1; -.
DR OMA; GMRVKKD; -.
DR OrthoDB; 1462697at2759; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C7E6; baseline and differential.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
PE 2: Evidence at transcript level;
KW ATP-binding; Helicase; Hydrolase; Nucleotide-binding; Reference proteome.
FT CHAIN 1..176
FT /note="Protein CURLY FLAG LEAF 2"
FT /id="PRO_0000456303"
FT DOMAIN 48..82
FT /note="WW"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00224"
FT MOTIF 41..46
FT /note="EAR"
FT /evidence="ECO:0000250|UniProtKB:Q9SRN4"
SQ SEQUENCE 176 AA; 19948 MW; 9A1616D56C6D05D9 CRC64;
MADITEYLER SMQNCSLIDR RSSMGDGFGM SDEHIPISDR FLELSSHFSV PSHLEQCLDL
KTGEIYYRSW NSGMRVKEDP RKSMSRGNYA DQSSGESSGT VFSSEEVSSY YESEESSSES
SPSSRKYHKE EQDEDVLVVA GCKACLMYFM VPKLFKDCPK CATQLLHFDQ LHSTSP
