CFM3_ORYSJ
ID CFM3_ORYSJ Reviewed; 886 AA.
AC Q2R1U8; Q0IRW0;
DT 17-FEB-2016, integrated into UniProtKB/Swiss-Prot.
DT 24-JAN-2006, sequence version 1.
DT 03-AUG-2022, entry version 75.
DE RecName: Full=CRM-domain containing factor CFM3, chloroplastic/mitochondrial {ECO:0000305};
DE AltName: Full=Protein CRM FAMILY MEMBER 3 {ECO:0000303|PubMed:18799595};
DE Short=OsCFM3 {ECO:0000303|PubMed:18799595};
DE Flags: Precursor;
GN Name=CFM3 {ECO:0000303|PubMed:18799595};
GN OrderedLocusNames=Os11g0592400 {ECO:0000312|EMBL:BAF28555.2},
GN LOC_Os11g37990 {ECO:0000312|EMBL:ABA94534.1};
GN ORFNames=OSNPB_110592400 {ECO:0000312|EMBL:BAT14685.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947 {ECO:0000312|EMBL:ABA94534.1};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16188032; DOI=10.1186/1741-7007-3-20;
RG The rice chromosomes 11 and 12 sequencing consortia;
RT "The sequence of rice chromosomes 11 and 12, rich in disease resistance
RT genes and recent gene duplications.";
RL BMC Biol. 3:20-20(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP FUNCTION, SUBCELLULAR LOCATION, AND DISRUPTION PHENOTYPE.
RX PubMed=18799595; DOI=10.1261/rna.1223708;
RA Asakura Y., Bayraktar O.A., Barkan A.;
RT "Two CRM protein subfamilies cooperate in the splicing of group IIB introns
RT in chloroplasts.";
RL RNA 14:2319-2332(2008).
CC -!- FUNCTION: Binds specific group II introns in chloroplasts and
CC facilitates their splicing. Acts on subgroup IIB introns. The
CC substrates of the subgroup IIB also require the CRM domain proteins
CC CAF1 or CAF2, with a simultaneous binding of CFM3 and CAF1 or CAF2
CC (PubMed:18799595). May influence the biogenesis of the mitochondrial
CC small ribosomal subunit (By similarity). {ECO:0000250|UniProtKB:F4J2U9,
CC ECO:0000269|PubMed:18799595}.
CC -!- SUBUNIT: Interacts with RNA. Part of large ribonucleo-protein particles
CC that contain CAF1 and/or CAF2, and RNC1.
CC {ECO:0000250|UniProtKB:A7XN92}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast
CC {ECO:0000269|PubMed:18799595}. Mitochondrion
CC {ECO:0000269|PubMed:18799595}.
CC -!- DISRUPTION PHENOTYPE: Albino leaves with little, if any, plastid rRNA.
CC {ECO:0000269|PubMed:18799595}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAF28555.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; DP000010; ABA94534.1; -; Genomic_DNA.
DR EMBL; AP008217; BAF28555.2; ALT_SEQ; Genomic_DNA.
DR EMBL; AP014967; BAT14685.1; -; Genomic_DNA.
DR RefSeq; XP_015616314.1; XM_015760828.1.
DR AlphaFoldDB; Q2R1U8; -.
DR SMR; Q2R1U8; -.
DR STRING; 4530.OS11T0592400-00; -.
DR PaxDb; Q2R1U8; -.
DR PRIDE; Q2R1U8; -.
DR EnsemblPlants; Os11t0592400-00; Os11t0592400-00; Os11g0592400.
DR GeneID; 4350825; -.
DR Gramene; Os11t0592400-00; Os11t0592400-00; Os11g0592400.
DR KEGG; osa:4350825; -.
DR eggNOG; KOG1990; Eukaryota.
DR HOGENOM; CLU_006310_3_1_1; -.
DR OMA; DLYNHTD; -.
DR OrthoDB; 505933at2759; -.
DR Proteomes; UP000000763; Chromosome 11.
DR Proteomes; UP000059680; Chromosome 11.
DR GO; GO:0009507; C:chloroplast; IDA:UniProtKB.
DR GO; GO:0005739; C:mitochondrion; IDA:UniProtKB.
DR GO; GO:0003729; F:mRNA binding; IEA:InterPro.
DR GO; GO:0000373; P:Group II intron splicing; IMP:UniProtKB.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 3.30.110.60; -; 3.
DR InterPro; IPR033262; CFM3.
DR InterPro; IPR045278; CRS1/CFM2/CFM3.
DR InterPro; IPR001890; RNA-binding_CRM.
DR InterPro; IPR035920; YhbY-like_sf.
DR PANTHER; PTHR31846; PTHR31846; 1.
DR PANTHER; PTHR31846:SF19; PTHR31846:SF19; 1.
DR Pfam; PF01985; CRS1_YhbY; 3.
DR SMART; SM01103; CRS1_YhbY; 3.
DR SUPFAM; SSF75471; SSF75471; 3.
DR PROSITE; PS51295; CRM; 3.
PE 3: Inferred from homology;
KW Chloroplast; Coiled coil; Mitochondrion; mRNA processing; mRNA splicing;
KW Plastid; Reference proteome; Repeat; Ribonucleoprotein; RNA-binding;
KW Transit peptide.
FT TRANSIT 1..70
FT /note="Chloroplast and mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 71..886
FT /note="CRM-domain containing factor CFM3,
FT chloroplastic/mitochondrial"
FT /id="PRO_0000435535"
FT DOMAIN 174..270
FT /note="CRM 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00626"
FT DOMAIN 378..475
FT /note="CRM 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00626"
FT DOMAIN 590..690
FT /note="CRM 3"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00626"
FT REGION 56..84
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 269..291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 771..886
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 269..283
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 773..787
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 792..830
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 833..852
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 866..886
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 886 AA; 99215 MW; 7FD3558F35C8B209 CRC64;
MAAAAMAISP SIHLHLHLHL HHPPRLHRLL HLSTTSPYPW LSAWPTAHRR RVPLRRPASA
LDLRPEPSPS SDSDDDAAFG TSRSSSRSAM SLILSRLRNS GYSYSPPELP PRPPRGSVED
VFRVDDGVVP NARGGFDDDA ESALVDARFP WELPMPPPEA GPRAARSKAW MAELTLPEAE
LRRLRHAGMR LKSRIKVGGA GVTREIVERI RDRWRNDEVV RIKVTGTPAL NMRLFHEILE
RKTGGLVIWR SGTSVSLYRG VAYDIPEPTK GTSKNTQTLG MKSSIKEPPG HSLLPNEKVN
EMQDNNGALV SNAEKDTLVE PVPEIKYEDE IDKLLDELGP RYDDWPRPDP SPVDADLLPA
TVPGYKPPFR VLPYGVRPSL SRRDTTNLRR LARGLPPHFA LGRSRQLQGL AAAMVKLWEK
SSIAKIALKR GVQLTTSERM AEDIKKLTGG VMLSRNNDFM VFYRGKDFLS PELAEKLLER
ERWAKSLQDE EQARLNAASS FSSRTEAPVE PTVAGTLGET LEANSKYGNK LDENYENKMT
RTVEAARHAD LVRKLEWKLQ LAQKKIEKAE RVLGKVETAL KPTEGIQPPE TITDEERFMF
RKLGLRMKAF LLLGRRGVFD GTIENMHLHW KYRELVKILV KAKSFGDVKK IALSLEAESG
GILVSVDKVS KGYAIVVFRG KDYARPSKLR PRNLLSKRKA LARSIEIQRR EALSHHIATL
NRRVKKLKAE LLQMEGVKEE GDVELYAKLD SAYSSDEEDV EDEDDEAYLR SFDNSVAVQN
GDDRTSLDGS DANSDDEGDY SDEDDDEDDD NDEEDGFDYE NDDEDDVPPT TSDGDLYNHT
DFGSSDSENY VSLSGRGDPD VKSKGSALDS RNSYSEQSTE LTNTCS
