ID   CFP32_MYCBO             Reviewed;         261 AA.
AC   P0A5N9; A0A1R3XVS1; O53774; X2BFF7;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 2.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Putative glyoxylase CFP32 {ECO:0000305};
DE   AltName: Full=27 kDa antigen Cfp30B {ECO:0000305};
GN   Name=cfp32 {ECO:0000250|UniProtKB:P9WIR3}; Synonyms=cfp30B, TB27.3;
GN   OrderedLocusNames=BQ2027_MB0592;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LT708304; SIT99189.1; -; Genomic_DNA.
DR   RefSeq; NP_854252.1; NC_002945.3.
DR   RefSeq; WP_003403012.1; NC_002945.4.
DR   AlphaFoldDB; P0A5N9; -.
DR   BMRB; P0A5N9; -.
DR   SMR; P0A5N9; -.
DR   PATRIC; fig|233413.5.peg.644; -.
DR   OMA; TVWTTYL; -.
DR   Proteomes; UP000001419; Chromosome.
DR   Gene3D; 3.10.180.10; -; 2.
DR   InterPro; IPR029068; Glyas_Bleomycin-R_OHBP_Dase.
DR   InterPro; IPR004360; Glyas_Fos-R_dOase_dom.
DR   InterPro; IPR041581; Glyoxalase_6.
DR   InterPro; IPR037523; VOC.
DR   Pfam; PF00903; Glyoxalase; 1.
DR   Pfam; PF18029; Glyoxalase_6; 1.
DR   SUPFAM; SSF54593; SSF54593; 2.
DR   PROSITE; PS51819; VOC; 2.
PE   4: Predicted;
KW   Repeat.
FT   CHAIN           1..261
FT                   /note="Putative glyoxylase CFP32"
FT                   /id="PRO_0000089564"
FT   DOMAIN          11..129
FT                   /note="VOC 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01163"
FT   DOMAIN          143..257
FT                   /note="VOC 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01163"
FT   REGION          13..123
FT                   /note="Glyoxalase 1"
FT                   /evidence="ECO:0000305"
FT   REGION          149..252
FT                   /note="Glyoxalase 2"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   261 AA;  27343 MW;  E0182A0B00461C76 CRC64;
     MPKRSEYRQG TPNWVDLQTT DQSAAKKFYT SLFGWGYDDN PVPGGGGVYS MATLNGEAVA
     AIAPMPPGAP EGMPPIWNTY IAVDDVDAVV DKVVPGGGQV MMPAFDIGDA GRMSFITDPT
     GAAVGLWQAN RHIGATLVNE TGTLIWNELL TDKPDLALAF YEAVVGLTHS SMEIAAGQNY
     RVLKAGDAEV GGCMEPPMPG VPNHWHVYFA VDDADATAAK AAAAGGQVIA EPADIPSVGR
     FAVLSDPQGA IFSVLKPAPQ Q