CG031_MOUSE
ID CG031_MOUSE Reviewed; 588 AA.
AC Q9D5Y0; Q8K4U1;
DT 05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=Uncharacterized protein C7orf31 homolog;
DE AltName: Full=Protein TISP74;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 402-588.
RC TISSUE=Testis;
RA Fujii T., Nishimune Y., Nojima H.;
RT "Mus musculus TISP74 mRNA.";
RL Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, microtubule organizing
CC center, centrosome {ECO:0000250|UniProtKB:Q8N865}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB97205.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AK014840; BAB29575.1; -; mRNA.
DR EMBL; BC055110; AAH55110.1; -; mRNA.
DR EMBL; AB045723; BAB97205.1; ALT_INIT; mRNA.
DR CCDS; CCDS20132.1; -.
DR RefSeq; NP_081840.1; NM_027564.3.
DR RefSeq; XP_006506668.1; XM_006506605.1.
DR AlphaFoldDB; Q9D5Y0; -.
DR STRING; 10090.ENSMUSP00000031852; -.
DR iPTMnet; Q9D5Y0; -.
DR PhosphoSitePlus; Q9D5Y0; -.
DR PaxDb; Q9D5Y0; -.
DR PRIDE; Q9D5Y0; -.
DR Antibodypedia; 12287; 57 antibodies from 19 providers.
DR DNASU; 70821; -.
DR Ensembl; ENSMUST00000031852; ENSMUSP00000031852; ENSMUSG00000029828.
DR GeneID; 70821; -.
DR KEGG; mmu:70821; -.
DR UCSC; uc009bxf.1; mouse.
DR MGI; MGI:1918071; 4921507P07Rik.
DR VEuPathDB; HostDB:ENSMUSG00000029828; -.
DR eggNOG; ENOG502QUAM; Eukaryota.
DR GeneTree; ENSGT00390000015236; -.
DR HOGENOM; CLU_038659_0_0_1; -.
DR InParanoid; Q9D5Y0; -.
DR OMA; DFPKCVE; -.
DR OrthoDB; 1113879at2759; -.
DR PhylomeDB; Q9D5Y0; -.
DR TreeFam; TF336164; -.
DR BioGRID-ORCS; 70821; 1 hit in 73 CRISPR screens.
DR PRO; PR:Q9D5Y0; -.
DR Proteomes; UP000000589; Chromosome 6.
DR RNAct; Q9D5Y0; protein.
DR Bgee; ENSMUSG00000029828; Expressed in seminiferous tubule of testis and 59 other tissues.
DR Genevisible; Q9D5Y0; MM.
DR GO; GO:0005813; C:centrosome; ISS:UniProtKB.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR InterPro; IPR027886; DUF4555.
DR PANTHER; PTHR31393; PTHR31393; 1.
DR Pfam; PF15093; DUF4555; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Cytoskeleton; Phosphoprotein; Reference proteome.
FT CHAIN 1..588
FT /note="Uncharacterized protein C7orf31 homolog"
FT /id="PRO_0000089588"
FT MOD_RES 219
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q6AYM0"
FT MOD_RES 406
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q6AYM0"
FT MOD_RES 421
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q6AYM0"
FT MOD_RES 427
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q6AYM0"
FT MOD_RES 441
FT /note="Phosphotyrosine"
FT /evidence="ECO:0000250|UniProtKB:Q6AYM0"
FT MOD_RES 457
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q6AYM0"
FT MOD_RES 484
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q6AYM0"
FT MOD_RES 516
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q6AYM0"
FT CONFLICT 402
FT /note="Q -> A (in Ref. 3)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 588 AA; 67661 MW; F42BC652664DD9AA CRC64;
MEVIHGRPHC CRNLEGADIL SNTFYSNGLH TPYETTIRPT ASQARYQELR EALPQCRLRW
GADREYGGVL PVSLPEEHRP KCEPPRLMSK GHQHYGFGGE IWPKKLPIEQ YYYMTQNKKS
DVYGNDSLLP KPPNSAVKEI CSPYPIEHPY HTHISRGSVF PTFTSPKDLY TGIKARTQQP
FPPTVPTKAC DTTILKTRGN PYRYELLDFP MDSKKKALTW PGQGVYYDFP KFVEKNKPVF
YPKPPKTFAP NSSVNPWDTM SSAKDANIQR NLERSHWLTS YAHDFTGLGP MSPLELDDYH
EKELAELTGQ IGFDPQPQEK FHPALKTPRP LDGRIARLTQ NQRPLEATVQ IPPPCPDCTP
RVLCAFHTFI PTSAEIMAMN NNLLSGITHK NQDVEEKIKE EQGLMSTCPL PTCYESKDLT
SLYDVQSFPK ITDTKKTDDL YWRQLEMKPL PISCSKSNHY IDYEPLKSAY RDPYAMCPNP
VRLSKSNILQ NKTDTADFTF DNFLSKPEFL GMNMESNEET RPLLDWIPRA GVPKHHSNLR
NLRNTFSKSM AQKRLHNSIQ EEQKDLRDKL QCGMRHQFFG YNGHHFYN
