CG057_MOUSE
ID CG057_MOUSE Reviewed; 291 AA.
AC Q5SS90;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 21-DEC-2004, sequence version 1.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=Uncharacterized protein C7orf57 homolog;
GN Name=Gm11992;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=NOD;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-50, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Kidney, and Testis;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
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DR EMBL; AK154909; BAE32919.1; -; mRNA.
DR EMBL; AL669837; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR CCDS; CCDS24431.1; -.
DR RefSeq; NP_001033017.1; NM_001037928.3.
DR AlphaFoldDB; Q5SS90; -.
DR iPTMnet; Q5SS90; -.
DR PhosphoSitePlus; Q5SS90; -.
DR MaxQB; Q5SS90; -.
DR PaxDb; Q5SS90; -.
DR PRIDE; Q5SS90; -.
DR ProteomicsDB; 281550; -.
DR Antibodypedia; 7300; 64 antibodies from 14 providers.
DR Ensembl; ENSMUST00000043285; ENSMUSP00000039806; ENSMUSG00000040978.
DR GeneID; 626870; -.
DR KEGG; mmu:626870; -.
DR UCSC; uc007hzv.1; mouse.
DR MGI; MGI:3651127; Gm11992.
DR VEuPathDB; HostDB:ENSMUSG00000040978; -.
DR eggNOG; ENOG502S6DP; Eukaryota.
DR GeneTree; ENSGT00390000014376; -.
DR HOGENOM; CLU_066025_0_0_1; -.
DR InParanoid; Q5SS90; -.
DR OMA; MVYEEFH; -.
DR OrthoDB; 1532915at2759; -.
DR PhylomeDB; Q5SS90; -.
DR TreeFam; TF330795; -.
DR BioGRID-ORCS; 626870; 1 hit in 64 CRISPR screens.
DR PRO; PR:Q5SS90; -.
DR Proteomes; UP000000589; Chromosome 11.
DR RNAct; Q5SS90; protein.
DR Bgee; ENSMUSG00000040978; Expressed in olfactory epithelium and 73 other tissues.
DR ExpressionAtlas; Q5SS90; baseline and differential.
DR Genevisible; Q5SS90; MM.
DR InterPro; IPR040247; DUF5524.
DR PANTHER; PTHR31097; PTHR31097; 1.
DR Pfam; PF17662; DUF5524; 1.
PE 1: Evidence at protein level;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..291
FT /note="Uncharacterized protein C7orf57 homolog"
FT /id="PRO_0000310992"
FT REGION 29..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 168..291
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 201..225
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..241
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 274..291
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 50
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:21183079"
SQ SEQUENCE 291 AA; 32895 MW; 995CD32698B610CE CRC64;
MRNTSKEVQS TSYRYAPCDW YYHLPVKRSE KPVGAPPASQ IPGLSDLRDS PNVNLPRARR
YWIKETDSEY VKLAKQGGRP DLLKHFAPGT RQGSPVAYSL PDWYIHHSKP PTSHQREVPV
VSIPDYMVYE EFNPDQANGS YESRQGPFDF DRKTIWQREA EELENVKRKV KLPAINSKNP
SKTGTPVSHK EPERSRLSLP PMPGQKNSSP TNFSKLISNG YKDEWLQQQK AEADRRTPKT
SRASVSSKST EDSKSNQDTE TPENPETPEG SEKTPDAEVS SPSESTPAEL K
