ID   CG11_CANAW              Reviewed;         698 AA.
AC   C4YR54; P24866;
DT   19-OCT-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=G1/S-specific cyclin CCN1;
GN   Name=CCN1; Synonyms=CLN1; ORFNames=CAWG_04553;
OS   Candida albicans (strain WO-1) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=294748;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WO-1;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-646.
RC   STRAIN=WO-1;
RX   PubMed=1409649; DOI=10.1073/pnas.89.20.9410;
RA   Whiteway M., Dignard D., Thomas D.Y.;
RT   "Dominant negative selection of heterologous genes: isolation of Candida
RT   albicans genes that interfere with Saccharomyces cerevisiae mating factor-
RT   induced cell cycle arrest.";
RL   Proc. Natl. Acad. Sci. U.S.A. 89:9410-9414(1992).
CC   -!- FUNCTION: Essential for the control of the cell cycle at the G1/S
CC       (start) transition. Interacts with the CDC2 protein kinase to form MPF.
CC   -!- SIMILARITY: Belongs to the cyclin family. {ECO:0000305}.
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DR   EMBL; CM000311; EEQ46207.1; -; Genomic_DNA.
DR   EMBL; M76587; AAA34330.2; -; Genomic_DNA.
DR   PIR; S49206; S49206.
DR   AlphaFoldDB; C4YR54; -.
DR   SMR; C4YR54; -.
DR   STRING; 5476.C4YR54; -.
DR   EnsemblFungi; EEQ46207; EEQ46207; CAWG_04553.
DR   VEuPathDB; FungiDB:CAWG_04553; -.
DR   HOGENOM; CLU_029626_0_0_1; -.
DR   OMA; QVINNFH; -.
DR   Proteomes; UP000001429; Chromosome 5.
DR   GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IEA:UniProt.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0000079; P:regulation of cyclin-dependent protein serine/threonine kinase activity; IEA:InterPro.
DR   GO; GO:2000045; P:regulation of G1/S transition of mitotic cell cycle; IEA:InterPro.
DR   CDD; cd00043; CYCLIN; 1.
DR   InterPro; IPR028857; CCNF_metazoan.
DR   InterPro; IPR039361; Cyclin.
DR   InterPro; IPR013763; Cyclin-like.
DR   InterPro; IPR036915; Cyclin-like_sf.
DR   InterPro; IPR004367; Cyclin_C-dom.
DR   InterPro; IPR014399; Cyclin_CLN.
DR   InterPro; IPR006671; Cyclin_N.
DR   PANTHER; PTHR10177; PTHR10177; 1.
DR   PANTHER; PTHR10177:SF252; PTHR10177:SF252; 1.
DR   Pfam; PF02984; Cyclin_C; 1.
DR   Pfam; PF00134; Cyclin_N; 1.
DR   PIRSF; PIRSF001770; Cyclin_CLN; 1.
DR   SMART; SM00385; CYCLIN; 1.
DR   SMART; SM01332; Cyclin_C; 1.
DR   SUPFAM; SSF47954; SSF47954; 2.
DR   PROSITE; PS00292; CYCLINS; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Cyclin.
FT   CHAIN           1..698
FT                   /note="G1/S-specific cyclin CCN1"
FT                   /id="PRO_0000413035"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          277..326
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          469..577
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          599..619
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          659..698
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        277..303
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        478..564
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   698 AA;  79299 MW;  97F693A73BC77264 CRC64;
     MTSLQQQQQQ QRVKYGPPHH IKRRPYHPIL ESLEFQTNQH LIQEYSLDIV NTLSQLESLT
     LVNPAMIDLQ PEIQWFMRPF LLDFLIELHS SFKLQPTTLF LCLNIIDRYC AKRIVFKRHY
     QLVGCTALWI ASKYEDKKSR VPTLKELTIM CRNAYDEEMF VQMEMHILST LDWSIGHPTL
     EDCLQLAIDS NNLSNNTTND IENKSVRPNR KSSISSAVTA VARFLCELSL YDKYFLSVPP
     SLIAITANLL SCSMLQIPHA SITLKNLIEQ EIINPQQKKQ KKAFSSNSSR TTTASYTHQN
     QSDVRHSSFD EDIDLDSGDE GDDDEDYIDE FYETNNYDDT NATTFDESIN KSTTINDENQ
     PPQIHTPFLS GLDEDSILSI KKICLMLIIQ LSKVTEVLSK KYENLGVIQV INNFHSNYKF
     IIQSIYENQE LLLNTINDST NNNEIDYKLI QSSEILLQFP KFDEYLTEDE DENVSTDDEA
     NSQPQGYDGS GSDGNNQLFT PKSPNAFSSN SSLTLNNHPQ SMVPVTPPSA TSQYSLFSNK
     NNRTHESTSG LNSTCNTPTH ISISSFAPPQ PPPGSILKPK LTSINSTNSL KIKKLTSNSN
     SSNINIHHGH HNTKQEKRYS HISIGSNSSS KYDGFSPIKS ISTNGSLITN NGSFTNIVNN
     TNSSSPLMNQ QQQYYHQQQH QQQVTQSSLY QHHHQYHQ