CGMA_RHIME
ID CGMA_RHIME Reviewed; 639 AA.
AC P72302;
DT 30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT 30-MAY-2000, sequence version 2.
DT 25-MAY-2022, entry version 112.
DE RecName: Full=Putative cyclic beta-1,2-glucan modification protein;
GN Name=cgmA; OrderedLocusNames=R01848; ORFNames=SMc00195;
OS Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS meliloti).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX NCBI_TaxID=266834;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=10419956; DOI=10.1128/jb.181.15.4576-4583.1999;
RA Wang P., Ingram-Smith C., Hadley J.A., Miller K.J.;
RT "Cloning, sequencing, and characterization of the cgmB gene of
RT Sinorhizobium meliloti involved in cyclic beta-glucan biosynthesis.";
RL J. Bacteriol. 181:4576-4583(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11481430; DOI=10.1073/pnas.161294398;
RA Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T.,
RA Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C.,
RA Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT "Analysis of the chromosome sequence of the legume symbiont Sinorhizobium
RT meliloti strain 1021.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=1021;
RX PubMed=11474104; DOI=10.1126/science.1060966;
RA Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA Wong K., Yeh K.-C., Batut J.;
RT "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL Science 293:668-672(2001).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- CAUTION: PubMed:10419956 reported that this protein is not expressed
CC and that the protein that transfers sn-1 phosphoglycerol substituents
CC to the cyclic beta-1,2-glucan backbone is CgmB. CgmB is encoded on the
CC opposite strand from cgmA and completely overlaps it. {ECO:0000305}.
CC -!- CAUTION: It is uncertain whether Met-1 or Val-52 is the initiator.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAB41532.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; U67998; AAB41532.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL591688; CAC46427.1; -; Genomic_DNA.
DR RefSeq; NP_385954.1; NC_003047.1.
DR RefSeq; WP_003534093.1; NC_003047.1.
DR AlphaFoldDB; P72302; -.
DR SMR; P72302; -.
DR STRING; 266834.SMc00195; -.
DR EnsemblBacteria; CAC46427; CAC46427; SMc00195.
DR GeneID; 61603318; -.
DR KEGG; sme:SMc00195; -.
DR PATRIC; fig|266834.11.peg.3290; -.
DR eggNOG; COG1368; Bacteria.
DR HOGENOM; CLU_014385_3_2_5; -.
DR OMA; LIQYDIT; -.
DR Proteomes; UP000001976; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008484; F:sulfuric ester hydrolase activity; IEA:InterPro.
DR Gene3D; 3.40.720.10; -; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR000917; Sulfatase_N.
DR Pfam; PF00884; Sulfatase; 1.
DR SUPFAM; SSF53649; SSF53649; 1.
PE 4: Predicted;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..639
FT /note="Putative cyclic beta-1,2-glucan modification
FT protein"
FT /id="PRO_0000089603"
FT TRANSMEM 34..54
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 69..89
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 96..116
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 144..164
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 185..205
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 227..247
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 639 AA; 72569 MW; 6E37EE267354C8AF CRC64;
MARIDSAVSS SQVYADGESS SARYTRTLSG ARSALFTLLI AIALVFTVEV IVRWSWPDTV
AYFADPMRPA WTTVAVFFLA MLGVDALFGR EHKAALLIAP LAVVPAFISQ QKQVFLSDPL
YPTDFLFGRQ IMELMPVLVK DRPWTAVGVV AGLIAAIVVG ALLLRFAWQN FPKLTRRERL
MRIAFALPLL VAFWNIMDYN QFSWIRDRLR VIPIMWDQTE NYRHNGFALA FAINLPMANV
NAPAGYMADA IDRIPVKPLP AGTTHRGKPD VIVLMSESFW DPTRLPKVKL TPDPMPTIRE
LQGGNVFSPE FGGMTANVEF EALTGFSNAF LPYGSIPYQQ YIRNPIPSLA TFFRGEGYVS
RAIHPFQGWF WNRTAVYKAF GFDMFRSEEN MPAMQKRGIF ASDESLTKEI IRQADEVEDP
FFFFAVTLQG HGPYEANRYA KNTIKVEGDL PEADRQVLAT YAQGVKEADD SLKMLMDWAK
ERDRETIIVL FGDHLPPLNT VYSSTGYMKG ITAERKGPKD QMKAEHETPL VVWSNKTGPK
KNIGTISPAF LSYQILKQAG YEHPYYTGFL GKVYDHYRVL DRYMLIRKNG KDVADWLRQP
KVPASLRDYR FLQHDMMFGK RYSTERFFKS HAELYSAGL
