ID   CGR1P_CANAL             Reviewed;         340 AA.
AC   P56553; A0A1D8PLN2; Q5AF85; Q5AFX1;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   06-MAR-2007, sequence version 2.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=Cell growth-regulated gene 1 protein;
GN   Name=CGR1; OrderedLocusNames=CAALFM_C402760CA;
GN   ORFNames=CaO19.10237, CaO19.2722;
OS   Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=237561;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=JCM 9061;
RX   PubMed=11342110; DOI=10.1016/s0167-4781(00)00243-8;
RA   Cho T., Sudoh M., Tanaka T., Nakashima Y., Chibana H., Kaminishi Y.;
RT   "Isolation and expression of a gene (CGR1) regulated during the yeast-
RT   hyphal transition in Candida albicans.";
RL   Biochim. Biophys. Acta 1517:288-292(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA   Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA   Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA   Scherer S.;
RT   "The diploid genome sequence of Candida albicans.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA   van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA   Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA   Chibana H., Nantel A., Magee P.T.;
RT   "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT   on the eight chromosomes.";
RL   Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=SC5314 / ATCC MYA-2876;
RX   PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA   Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT   "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT   specific measurements and provides a simple model for repeat and indel
RT   structure.";
RL   Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC   -!- FUNCTION: Involved in the cell growth regulation.
CC   -!- SIMILARITY: Belongs to the SMP-30/CGR1 family. {ECO:0000305}.
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DR   EMBL; AB013716; BAA28176.1; -; Genomic_DNA.
DR   EMBL; CP017626; AOW29043.1; -; Genomic_DNA.
DR   RefSeq; XP_720472.2; XM_715379.2.
DR   AlphaFoldDB; P56553; -.
DR   SMR; P56553; -.
DR   BioGRID; 1220947; 1.
DR   STRING; 237561.P56553; -.
DR   GeneID; 3637853; -.
DR   KEGG; cal:CAALFM_C402760CA; -.
DR   CGD; CAL0000196952; CGR1.
DR   VEuPathDB; FungiDB:C4_02760C_A; -.
DR   eggNOG; KOG4499; Eukaryota.
DR   HOGENOM; CLU_036110_3_0_1; -.
DR   InParanoid; P56553; -.
DR   OrthoDB; 1343872at2759; -.
DR   PRO; PR:P56553; -.
DR   Proteomes; UP000000559; Chromosome 4.
DR   GO; GO:0005509; F:calcium ion binding; IBA:GO_Central.
DR   GO; GO:0004341; F:gluconolactonase activity; IBA:GO_Central.
DR   GO; GO:0019853; P:L-ascorbic acid biosynthetic process; IBA:GO_Central.
DR   GO; GO:0030308; P:negative regulation of cell growth; IEP:CGD.
DR   Gene3D; 2.120.10.30; -; 1.
DR   InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR   InterPro; IPR013658; SGL.
DR   InterPro; IPR005511; SMP-30.
DR   Pfam; PF08450; SGL; 1.
DR   PRINTS; PR01790; SMP30FAMILY.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..340
FT                   /note="Cell growth-regulated gene 1 protein"
FT                   /id="PRO_0000173051"
FT   CONFLICT        52..54
FT                   /note="INT -> TNI (in Ref. 1; BAA28176)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        206
FT                   /note="D -> N (in Ref. 1; BAA28176)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        233
FT                   /note="P -> S (in Ref. 1; BAA28176)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   340 AA;  38414 MW;  4A824993A13ECBF9 CRC64;
     MSLTITKDNI FPKGYRGRLT EGVTYDERNN TLLWVDIIQG EVHRVFLDNT NINTNTSSSS
     HETLKWDSSN ESIGAICLTN DPNKLIICSK YGLAYGDFSS STIEYFFKYP HTTNPDEKLR
     LRSNDGIIDP WGNLWIGVMN DFPIGAKEGI QPEGKLYRIG FSKESNKLTC DVMIENSLIS
     NGLCFNNQGD EFYWTDSLTF KIWKYDYDKT TNKLTNKSVF IDLKQFYPDV EQPEPDGLVM
     TNNGEIYTCV FSTGTILHVD NQGKEIERIK IAAKRPTCVT IGSGIKNNEM FVTTGHLKLD
     DEKATIDAIN LDGDLGGFLF KLKVDKDLNG QKKNIWGGKV