CGR1_CANAL
ID CGR1_CANAL Reviewed; 135 AA.
AC Q59WI7; A0A1D8PF07;
DT 06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT 26-APR-2005, sequence version 1.
DT 03-AUG-2022, entry version 69.
DE RecName: Full=rRNA-processing protein CGR1;
GN Name=CGR1; OrderedLocusNames=CAALFM_C111000CA;
GN ORFNames=CaO19.2314, CaO19.9850;
OS Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=237561;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA Scherer S.;
RT "The diploid genome sequence of Candida albicans.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA Chibana H., Nantel A., Magee P.T.;
RT "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT on the eight chromosomes.";
RL Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT specific measurements and provides a simple model for repeat and indel
RT structure.";
RL Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC -!- FUNCTION: Involved in nucleolar integrity and required for processing
CC of the pre-rRNA for the 60S ribosome subunit. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the CGR1 family. {ECO:0000305}.
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DR EMBL; CP017623; AOW26726.1; -; Genomic_DNA.
DR RefSeq; XP_713919.1; XM_708826.1.
DR AlphaFoldDB; Q59WI7; -.
DR SMR; Q59WI7; -.
DR STRING; 237561.Q59WI7; -.
DR GeneID; 3644422; -.
DR KEGG; cal:CAALFM_C111000CA; -.
DR CGD; CAL0000173953; orf19.9850.
DR VEuPathDB; FungiDB:C1_11000C_A; -.
DR eggNOG; ENOG502S7VB; Eukaryota.
DR HOGENOM; CLU_125051_0_1_1; -.
DR OMA; NGKQWHD; -.
DR OrthoDB; 1643480at2759; -.
DR PRO; PR:Q59WI7; -.
DR Proteomes; UP000000559; Chromosome 1.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR InterPro; IPR005579; Cgr1-like.
DR Pfam; PF03879; Cgr1; 1.
PE 3: Inferred from homology;
KW Coiled coil; Nucleus; Reference proteome; Ribosome biogenesis;
KW rRNA processing.
FT CHAIN 1..135
FT /note="rRNA-processing protein CGR1"
FT /id="PRO_0000278949"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 110..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 60..118
FT /evidence="ECO:0000255"
FT COMPBIAS 16..33
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 135 AA; 16280 MW; 024EC0F2B79BC5DA CRC64;
MSSSSNLQYE EIPKKYIDPL APKDKGEGSR VNGKDWKIKK DAFRVKTLGV VSKTKKDSFK
QRELKRLEEE QYKARLKELK DEKESAKNQR IADLKRRREI KAEKERYERM ATKMHAKKVE
RMRKREKRNK LLKER
