ID   CGR1_CRYNB              Reviewed;         127 AA.
AC   P0CM67; Q55SP5; Q5KH33;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   28-JUN-2011, sequence version 1.
DT   25-MAY-2022, entry version 25.
DE   RecName: Full=rRNA-processing protein CGR1;
GN   Name=CGR1; OrderedLocusNames=CNBE1390;
OS   Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)
OS   (Filobasidiella neoformans).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Tremellales; Cryptococcaceae; Cryptococcus;
OC   Cryptococcus neoformans species complex.
OX   NCBI_TaxID=283643;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B-3501A;
RX   PubMed=15653466; DOI=10.1126/science.1103773;
RA   Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D.,
RA   Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E.,
RA   Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., D'Souza C.A.,
RA   Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., Huang J.C.,
RA   Janbon G., Jones S.J.M., Koo H.L., Krzywinski M.I., Kwon-Chung K.J.,
RA   Lengeler K.B., Maiti R., Marra M.A., Marra R.E., Mathewson C.A.,
RA   Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., Schein J.E.,
RA   Shvartsbeyn A., Shin H., Shumway M., Specht C.A., Suh B.B., Tenney A.,
RA   Utterback T.R., Wickes B.L., Wortman J.R., Wye N.H., Kronstad J.W.,
RA   Lodge J.K., Heitman J., Davis R.W., Fraser C.M., Hyman R.W.;
RT   "The genome of the basidiomycetous yeast and human pathogen Cryptococcus
RT   neoformans.";
RL   Science 307:1321-1324(2005).
CC   -!- FUNCTION: Involved in nucleolar integrity and required for processing
CC       of the pre-rRNA for the 60S ribosome subunit. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CGR1 family. {ECO:0000305}.
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DR   EMBL; AAEY01000024; EAL20776.1; -; Genomic_DNA.
DR   RefSeq; XP_775423.1; XM_770330.1.
DR   AlphaFoldDB; P0CM67; -.
DR   SMR; P0CM67; -.
DR   EnsemblFungi; AAW43439; AAW43439; CNE01440.
DR   EnsemblFungi; EAL20776; EAL20776; CNBE1390.
DR   GeneID; 4936147; -.
DR   KEGG; cnb:CNBE1390; -.
DR   VEuPathDB; FungiDB:CNBE1390; -.
DR   HOGENOM; CLU_125051_1_0_1; -.
DR   Proteomes; UP000001435; Chromosome 5.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   InterPro; IPR005579; Cgr1-like.
DR   Pfam; PF03879; Cgr1; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Nucleus; Ribosome biogenesis; rRNA processing.
FT   CHAIN           1..127
FT                   /note="rRNA-processing protein CGR1"
FT                   /id="PRO_0000410036"
FT   REGION          1..127
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          52..114
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..22
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        51..109
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        110..127
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   127 AA;  14530 MW;  16DC3E38566FD7A8 CRC64;
     MSAEPSSSAQ ASAPTVVSVA PSKNGRTPGK AHKSAKTALR RSYISPSVKT PFEKRMEKEK
     AQQAAKQLEK ELKEEKENER QRKVNIIKER RARKEEKQRE EELRAKMSAK KLQRMKKREG
     RSKKING