CGR1_EMENI
ID CGR1_EMENI Reviewed; 114 AA.
AC Q9Y708; C8VLT9;
DT 06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 2.
DT 25-MAY-2022, entry version 73.
DE RecName: Full=rRNA-processing protein cgrA;
GN Name=cgrA; Synonyms=cgr1; ORFNames=AN11145;
OS Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 /
OS M139) (Aspergillus nidulans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Nidulantes.
OX NCBI_TaxID=227321;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=9773270; DOI=10.3109/10425179809050019;
RA Sun J., Rhodes J.C., Askew D.S.;
RT "Sequencing of a gene encoding a member of the mitochondrial carrier family
RT of transport proteins from Aspergillus nidulans.";
RL DNA Seq. 9:1-8(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND SUBCELLULAR LOCATION.
RX PubMed=11381331; DOI=10.1007/s002840010237;
RA Sun J., Boettner D., Huebner N., Xu F., Rhodes J.C., Askew D.S.;
RT "Molecular cloning of cgrA, the gene encoding the Aspergillus nidulans
RT ortholog of Saccharomyces cerevisiae CGR1.";
RL Curr. Microbiol. 42:403-407(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=16372000; DOI=10.1038/nature04341;
RA Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S.,
RA Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V.,
RA Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S.,
RA Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H.,
RA Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K.,
RA Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R.,
RA Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C.,
RA Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L.,
RA Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
RT "Sequencing of Aspergillus nidulans and comparative analysis with A.
RT fumigatus and A. oryzae.";
RL Nature 438:1105-1115(2005).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139;
RX PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003;
RA Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J.,
RA Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., von Dohren H.,
RA Doonan J., Driessen A.J., Durek P., Espeso E., Fekete E., Flipphi M.,
RA Estrada C.G., Geysens S., Goldman G., de Groot P.W., Hansen K.,
RA Harris S.D., Heinekamp T., Helmstaedt K., Henrissat B., Hofmann G.,
RA Homan T., Horio T., Horiuchi H., James S., Jones M., Karaffa L.,
RA Karanyi Z., Kato M., Keller N., Kelly D.E., Kiel J.A., Kim J.M.,
RA van der Klei I.J., Klis F.M., Kovalchuk A., Krasevec N., Kubicek C.P.,
RA Liu B., Maccabe A., Meyer V., Mirabito P., Miskei M., Mos M., Mullins J.,
RA Nelson D.R., Nielsen J., Oakley B.R., Osmani S.A., Pakula T., Paszewski A.,
RA Paulsen I., Pilsyk S., Pocsi I., Punt P.J., Ram A.F., Ren Q., Robellet X.,
RA Robson G., Seiboth B., van Solingen P., Specht T., Sun J.,
RA Taheri-Talesh N., Takeshita N., Ussery D., vanKuyk P.A., Visser H.,
RA van de Vondervoort P.J., de Vries R.P., Walton J., Xiang X., Xiong Y.,
RA Zeng A.P., Brandt B.W., Cornell M.J., van den Hondel C.A., Visser J.,
RA Oliver S.G., Turner G.;
RT "The 2008 update of the Aspergillus nidulans genome annotation: a community
RT effort.";
RL Fungal Genet. Biol. 46:S2-13(2009).
CC -!- FUNCTION: Involved in nucleolar integrity and required for processing
CC of the pre-rRNA for the 60S ribosome subunit. {ECO:0000250,
CC ECO:0000269|PubMed:11381331}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the CGR1 family. {ECO:0000305}.
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DR EMBL; AF146189; AAD44762.2; -; Genomic_DNA.
DR EMBL; AF146190; AAD44764.2; -; mRNA.
DR EMBL; AACD01000164; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BN001307; CBF84743.1; -; Genomic_DNA.
DR AlphaFoldDB; Q9Y708; -.
DR SMR; Q9Y708; -.
DR STRING; 162425.CADANIAP00007989; -.
DR EnsemblFungi; CBF84743; CBF84743; ANIA_11145.
DR VEuPathDB; FungiDB:AN11145; -.
DR eggNOG; ENOG502S7VB; Eukaryota.
DR HOGENOM; CLU_125051_0_0_1; -.
DR InParanoid; Q9Y708; -.
DR OMA; NGKQWHD; -.
DR OrthoDB; 1643480at2759; -.
DR Proteomes; UP000000560; Chromosome VII.
DR Proteomes; UP000005890; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IDA:AspGD.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR InterPro; IPR005579; Cgr1-like.
DR Pfam; PF03879; Cgr1; 1.
PE 3: Inferred from homology;
KW Coiled coil; Nucleus; Reference proteome; Ribosome biogenesis;
KW rRNA processing.
FT CHAIN 1..114
FT /note="rRNA-processing protein cgrA"
FT /id="PRO_0000278955"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 77..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 40..101
FT /evidence="ECO:0000255"
FT COMPBIAS 77..95
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 114 AA; 13595 MW; AE88EF3735F6104C CRC64;
MSSAAPAPST HAAKSIRKNG KNWHDNKKPF RPNGGLTSYT KRAAARKEQE AIKEYEKELR
EEREAERQAH IQRIKERRAA KEEKERYEKM AEKMHRKRVE RLKKREKRNK LLNS
