ID   CGR1_KLULA              Reviewed;         121 AA.
AC   Q6CNQ3;
DT   06-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=rRNA-processing protein CGR1;
GN   Name=CGR1; OrderedLocusNames=KLLA0E10769g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in nucleolar integrity and required for processing
CC       of the pre-rRNA for the 60S ribosome subunit. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CGR1 family. {ECO:0000305}.
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DR   EMBL; CR382125; CAG99523.1; -; Genomic_DNA.
DR   RefSeq; XP_454436.1; XM_454436.1.
DR   AlphaFoldDB; Q6CNQ3; -.
DR   SMR; Q6CNQ3; -.
DR   STRING; 28985.XP_454436.1; -.
DR   EnsemblFungi; CAG99523; CAG99523; KLLA0_E10781g.
DR   GeneID; 2893657; -.
DR   KEGG; kla:KLLA0_E10781g; -.
DR   eggNOG; ENOG502S7VB; Eukaryota.
DR   HOGENOM; CLU_125051_0_1_1; -.
DR   InParanoid; Q6CNQ3; -.
DR   OMA; NGKQWHD; -.
DR   Proteomes; UP000000598; Chromosome E.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR   InterPro; IPR005579; Cgr1-like.
DR   Pfam; PF03879; Cgr1; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Nucleus; Reference proteome; Ribosome biogenesis;
KW   rRNA processing.
FT   CHAIN           1..121
FT                   /note="rRNA-processing protein CGR1"
FT                   /id="PRO_0000278957"
FT   COILED          48..104
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   121 AA;  14591 MW;  4D05AC154583F8B6 CRC64;
     MSDNTAEQQD IQIKGKPVSG RTWKVEKEPL RAKNRVVKNK KLTSWELKKQ KRLEDQQFKE
     KVRALKEEKK AEKDAVIQAL KERRAKKEEQ ERYDRLAAKM HAKKVDRLRR REKRNKALKE
     R