CH033_MOUSE
ID CH033_MOUSE Reviewed; 222 AA.
AC Q3U6N9; Q3URI5; Q9D0Z5;
DT 02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2005, sequence version 1.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=UPF0488 protein C8orf33 homolog;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2 AND 3).
RC STRAIN=C57BL/6J; TISSUE=Bone marrow, Embryo, and Head;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
RC STRAIN=Czech II; TISSUE=Mammary tumor;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=3;
CC Name=1;
CC IsoId=Q3U6N9-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q3U6N9-2; Sequence=VSP_028170, VSP_028171;
CC Name=3;
CC IsoId=Q3U6N9-3; Sequence=VSP_028170;
CC -!- SIMILARITY: Belongs to the UPF0488 family. {ECO:0000305}.
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DR EMBL; AK004154; BAB23195.1; -; mRNA.
DR EMBL; AK141496; BAE24703.1; -; mRNA.
DR EMBL; AK153059; BAE31685.1; -; mRNA.
DR EMBL; AK160695; BAE35959.1; -; mRNA.
DR EMBL; BC038324; AAH38324.1; -; mRNA.
DR EMBL; BC091734; AAH91734.1; -; mRNA.
DR CCDS; CCDS84175.1; -. [Q3U6N9-1]
DR CCDS; CCDS88794.1; -. [Q3U6N9-3]
DR RefSeq; NP_001334469.1; NM_001347540.1. [Q3U6N9-1]
DR RefSeq; NP_473440.1; NM_054099.2. [Q3U6N9-3]
DR AlphaFoldDB; Q3U6N9; -.
DR SMR; Q3U6N9; -.
DR iPTMnet; Q3U6N9; -.
DR PhosphoSitePlus; Q3U6N9; -.
DR EPD; Q3U6N9; -.
DR MaxQB; Q3U6N9; -.
DR PaxDb; Q3U6N9; -.
DR PeptideAtlas; Q3U6N9; -.
DR PRIDE; Q3U6N9; -.
DR Antibodypedia; 28690; 77 antibodies from 12 providers.
DR DNASU; 117171; -.
DR Ensembl; ENSMUST00000071792; ENSMUSP00000071698; ENSMUSG00000063236. [Q3U6N9-1]
DR Ensembl; ENSMUST00000229229; ENSMUSP00000155387; ENSMUSG00000063236. [Q3U6N9-2]
DR Ensembl; ENSMUST00000230274; ENSMUSP00000154907; ENSMUSG00000063236. [Q3U6N9-3]
DR GeneID; 117171; -.
DR KEGG; mmu:117171; -.
DR UCSC; uc007wmv.1; mouse. [Q3U6N9-1]
DR UCSC; uc011zvd.1; mouse. [Q3U6N9-2]
DR MGI; MGI:2152337; 1110038F14Rik.
DR VEuPathDB; HostDB:ENSMUSG00000063236; -.
DR eggNOG; ENOG502S1RU; Eukaryota.
DR GeneTree; ENSGT00390000000306; -.
DR HOGENOM; CLU_082144_1_1_1; -.
DR InParanoid; Q3U6N9; -.
DR OMA; EFRFSFF; -.
DR OrthoDB; 1632971at2759; -.
DR PhylomeDB; Q3U6N9; -.
DR TreeFam; TF326272; -.
DR BioGRID-ORCS; 117171; 3 hits in 65 CRISPR screens.
DR PRO; PR:Q3U6N9; -.
DR Proteomes; UP000000589; Chromosome 15.
DR RNAct; Q3U6N9; protein.
DR Bgee; ENSMUSG00000063236; Expressed in cleaving embryo and 261 other tissues.
DR Genevisible; Q3U6N9; MM.
DR InterPro; IPR029274; DUF4615.
DR PANTHER; PTHR13602; PTHR13602; 1.
DR Pfam; PF15393; DUF4615; 1.
PE 2: Evidence at transcript level;
KW Acetylation; Alternative splicing; Methylation; Phosphoprotein;
KW Reference proteome.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250|UniProtKB:Q9H7E9"
FT CHAIN 2..222
FT /note="UPF0488 protein C8orf33 homolog"
FT /id="PRO_0000304983"
FT REGION 1..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 119..146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 186..210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 192..210
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 2
FT /note="N-acetylalanine"
FT /evidence="ECO:0000250|UniProtKB:Q9H7E9"
FT MOD_RES 27
FT /note="Omega-N-methylarginine"
FT /evidence="ECO:0000250|UniProtKB:Q9H7E9"
FT MOD_RES 75
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9H7E9"
FT VAR_SEQ 1..62
FT /note="Missing (in isoform 2 and isoform 3)"
FT /evidence="ECO:0000303|PubMed:15489334,
FT ECO:0000303|PubMed:16141072"
FT /id="VSP_028170"
FT VAR_SEQ 129
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:16141072"
FT /id="VSP_028171"
SQ SEQUENCE 222 AA; 24465 MW; 53D7B2DE0876A60C CRC64;
MAEPGRPARE APAASSRKTH RAPRRPRPSR SASGASEPPL RSSVQPACDS AAGTHPVGNT
VAMKQKKKKT PNRVSGTNGS EKPSEKPAPD EAPPSAEAQA EQLARELAWC VEQLELGLKT
QRPTPKQKEQ AVGAIRTLRS EKTPLPRKRQ LMRSLFGDYR AQMDAEWREA LRALKAATHS
AQVQLVSEAT RKKSGRVCRP RPAERAKTTP DLTSEEFRFN FF
