ID   CH076_MOUSE             Reviewed;         372 AA.
AC   Q9D2X8;
DT   07-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 125.
DE   RecName: Full=Uncharacterized protein C8orf76 homolog;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=BALB/cJ;
RA   Tian W., Mcintyre T., Strober W., Chu C.C.;
RT   "A new gene cloned from mouse B cells.";
RL   Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J, and NOD; TISSUE=Cecum, Head, and Spleen;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [4]
RP   PROTEIN SEQUENCE OF 281-291, AND IDENTIFICATION BY MASS SPECTROMETRY.
RC   STRAIN=OF1; TISSUE=Hippocampus;
RA   Lubec G., Sunyer B., Chen W.-Q.;
RL   Submitted (JAN-2009) to UniProtKB.
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DR   EMBL; AY053393; AAL15447.1; -; mRNA.
DR   EMBL; AK018655; BAB31327.1; -; mRNA.
DR   EMBL; AK047927; BAC33192.1; -; mRNA.
DR   EMBL; AK089715; BAC40947.1; -; mRNA.
DR   EMBL; AK167012; BAE39188.1; -; mRNA.
DR   EMBL; BC050895; AAH50895.1; -; mRNA.
DR   CCDS; CCDS37078.1; -.
DR   RefSeq; NP_083694.1; NM_029418.4.
DR   AlphaFoldDB; Q9D2X8; -.
DR   SMR; Q9D2X8; -.
DR   STRING; 10090.ENSMUSP00000098220; -.
DR   iPTMnet; Q9D2X8; -.
DR   PhosphoSitePlus; Q9D2X8; -.
DR   EPD; Q9D2X8; -.
DR   MaxQB; Q9D2X8; -.
DR   PaxDb; Q9D2X8; -.
DR   PeptideAtlas; Q9D2X8; -.
DR   PRIDE; Q9D2X8; -.
DR   DNASU; 75758; -.
DR   Ensembl; ENSMUST00000100655; ENSMUSP00000098220; ENSMUSG00000101892.
DR   GeneID; 75758; -.
DR   KEGG; mmu:75758; -.
DR   UCSC; uc007vta.1; mouse.
DR   MGI; MGI:1923008; 9130401M01Rik.
DR   VEuPathDB; HostDB:ENSMUSG00000101892; -.
DR   eggNOG; ENOG502QW95; Eukaryota.
DR   GeneTree; ENSGT00390000011435; -.
DR   HOGENOM; CLU_044858_0_0_1; -.
DR   InParanoid; Q9D2X8; -.
DR   OMA; IKDEVHP; -.
DR   OrthoDB; 1578065at2759; -.
DR   PhylomeDB; Q9D2X8; -.
DR   TreeFam; TF332319; -.
DR   BioGRID-ORCS; 75758; 4 hits in 72 CRISPR screens.
DR   PRO; PR:Q9D2X8; -.
DR   Proteomes; UP000000589; Chromosome 15.
DR   RNAct; Q9D2X8; protein.
DR   Bgee; ENSMUSG00000101892; Expressed in embryonic facial prominence and 66 other tissues.
DR   ExpressionAtlas; Q9D2X8; baseline and differential.
DR   Genevisible; Q9D2X8; MM.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR041404; DUF5588.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR31919; PTHR31919; 1.
DR   Pfam; PF17826; DUF5588; 1.
DR   SUPFAM; SSF48452; SSF48452; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Reference proteome.
FT   CHAIN           1..372
FT                   /note="Uncharacterized protein C8orf76 homolog"
FT                   /id="PRO_0000225636"
FT   REGION          183..212
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        186..212
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   372 AA;  41643 MW;  D4EFCE1BFF81520C CRC64;
     METGCWVLGG EFEDSVFEQR PERRPEPPSP YRAKLCEPQW FYEETECSDD IEVLTLKKFR
     GDLAYRRQEY EKALQEYSSI SEQLPSTNFA MKRDVQEGQA RCLAHLGRHE EALEMAADLE
     SKATNTDHLT VVLHLHLAVF SSLQSREHTI LCLHKLIALH PLNPWSWCKL AEAYLSPGPG
     LPAGVSPQGQ KSSASSDKAV GPSSVHSGTG SLLSLPTTLP ENALLSVEAS GSAQENMPSL
     ARRREEAQME ARRKACASLL RARLLLQLAQ SQQTSFALEK NLRTQQEIAG KVKDFNFRED
     TLLLMEEAMG EDIVPEKIKE ELHSEVKCVG PGALTAMVVA SSKEFEDKWF RKIKDHFCPL
     GNQFHVEVEI IA