ID   CH088_HUMAN             Reviewed;         117 AA.
AC   P0DMB2;
DT   22-JAN-2014, integrated into UniProtKB/Swiss-Prot.
DT   22-JAN-2014, sequence version 1.
DT   03-AUG-2022, entry version 45.
DE   RecName: Full=Uncharacterized protein C8orf88;
GN   Name=C8orf88;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Eye;
RX   PubMed=16368877; DOI=10.1152/physiolgenomics.00121.2005;
RA   Choy K.W., Wang C.C., Ogura A., Lau T.K., Rogers M.S., Ikeo K.,
RA   Gojobori T., Lam D.S., Pang C.P.;
RT   "Genomic annotation of 15,809 ESTs identified from pooled early gestation
RT   human eyes.";
RL   Physiol. Genomics 25:9-15(2006).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16421571; DOI=10.1038/nature04406;
RA   Nusbaum C., Mikkelsen T.S., Zody M.C., Asakawa S., Taudien S., Garber M.,
RA   Kodira C.D., Schueler M.G., Shimizu A., Whittaker C.A., Chang J.L.,
RA   Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., Allen N.R., Anderson S.,
RA   Asakawa T., Blechschmidt K., Bloom T., Borowsky M.L., Butler J., Cook A.,
RA   Corum B., DeArellano K., DeCaprio D., Dooley K.T., Dorris L. III,
RA   Engels R., Gloeckner G., Hafez N., Hagopian D.S., Hall J.L., Ishikawa S.K.,
RA   Jaffe D.B., Kamat A., Kudoh J., Lehmann R., Lokitsang T., Macdonald P.,
RA   Major J.E., Matthews C.D., Mauceli E., Menzel U., Mihalev A.H.,
RA   Minoshima S., Murayama Y., Naylor J.W., Nicol R., Nguyen C., O'Leary S.B.,
RA   O'Neill K., Parker S.C.J., Polley A., Raymond C.K., Reichwald K.,
RA   Rodriguez J., Sasaki T., Schilhabel M., Siddiqui R., Smith C.L.,
RA   Sneddon T.P., Talamas J.A., Tenzin P., Topham K., Venkataraman V., Wen G.,
RA   Yamazaki S., Young S.K., Zeng Q., Zimmer A.R., Rosenthal A., Birren B.W.,
RA   Platzer M., Shimizu N., Lander E.S.;
RT   "DNA sequence and analysis of human chromosome 8.";
RL   Nature 439:331-335(2006).
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DR   EMBL; BY799545; -; NOT_ANNOTATED_CDS; mRNA.
DR   EMBL; AC087439; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC103770; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS59105.1; -.
DR   RefSeq; NP_001177901.1; NM_001190972.1.
DR   RefSeq; XP_016868428.1; XM_017012939.1.
DR   AlphaFoldDB; P0DMB2; -.
DR   IntAct; P0DMB2; 1.
DR   STRING; 9606.ENSP00000454561; -.
DR   iPTMnet; P0DMB2; -.
DR   PhosphoSitePlus; P0DMB2; -.
DR   BioMuta; C8orf88; -.
DR   EPD; P0DMB2; -.
DR   MassIVE; P0DMB2; -.
DR   PaxDb; P0DMB2; -.
DR   PeptideAtlas; P0DMB2; -.
DR   PRIDE; P0DMB2; -.
DR   Antibodypedia; 73915; 1 antibodies from 1 providers.
DR   DNASU; 100127983; -.
DR   Ensembl; ENST00000517562.3; ENSP00000454561.1; ENSG00000253250.3.
DR   GeneID; 100127983; -.
DR   KEGG; hsa:100127983; -.
DR   MANE-Select; ENST00000517562.3; ENSP00000454561.1; NM_001190972.2; NP_001177901.1.
DR   UCSC; uc022axl.2; human.
DR   CTD; 100127983; -.
DR   DisGeNET; 100127983; -.
DR   GeneCards; C8orf88; -.
DR   HGNC; HGNC:44672; C8orf88.
DR   HPA; ENSG00000253250; Tissue enhanced (testis).
DR   neXtProt; NX_P0DMB2; -.
DR   OpenTargets; ENSG00000253250; -.
DR   VEuPathDB; HostDB:ENSG00000253250; -.
DR   eggNOG; ENOG502S4NM; Eukaryota.
DR   GeneTree; ENSGT00530000068397; -.
DR   HOGENOM; CLU_1969739_0_0_1; -.
DR   OMA; GPVFPFN; -.
DR   OrthoDB; 1587625at2759; -.
DR   PathwayCommons; P0DMB2; -.
DR   BioGRID-ORCS; 100127983; 10 hits in 963 CRISPR screens.
DR   Pharos; P0DMB2; Tdark.
DR   PRO; PR:P0DMB2; -.
DR   Proteomes; UP000005640; Chromosome 8.
DR   RNAct; P0DMB2; protein.
DR   Bgee; ENSG00000253250; Expressed in cauda epididymis and 168 other tissues.
DR   Genevisible; P0DMB2; HS.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0008190; F:eukaryotic initiation factor 4E binding; IBA:GO_Central.
DR   GO; GO:0045947; P:negative regulation of translational initiation; IBA:GO_Central.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..117
FT                   /note="Uncharacterized protein C8orf88"
FT                   /id="PRO_0000425157"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   117 AA;  13372 MW;  915DA057D291B2F2 CRC64;
     METKKLIGKP LQPARPVRHL TSPPGAVFPF NFQNEYPCNT QCIQSGVSRC KTNGMQAFSQ
     GLNEQQQQQS PVKKERIKYS RDFLLKLSSV SICRKKPDFL PDHPIVLQKP ENNQSFK