ID   CH0_CONBY               Reviewed;          78 AA.
AC   P0DTJ9;
DT   23-FEB-2022, integrated into UniProtKB/Swiss-Prot.
DT   23-FEB-2022, sequence version 1.
DT   03-AUG-2022, entry version 2.
DE   RecName: Full=Conotoxin ba1890.8 {ECO:0000303|PubMed:33916793};
DE   Contains:
DE     RecName: Full=Conotoxin ba1560.9 {ECO:0000303|PubMed:33916793};
DE   Flags: Precursor;
OS   Conus bayani (Bayan's cone) (Stellaconus bayani).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Caenogastropoda; Neogastropoda; Conoidea; Conidae; Conus; Splinoconus.
OX   NCBI_TaxID=2070216;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 62-75, MASS SPECTROMETRY,
RP   SUBCELLULAR LOCATION, AND PYROGLUTAMATE FORMATION AT GLN-62.
RC   TISSUE=Venom, and Venom duct;
RX   PubMed=33916793; DOI=10.3390/md19040202;
RA   Rajaian Pushpabai R., Wilson Alphonse C.R., Mani R., Arun Apte D.,
RA   Franklin J.B.;
RT   "Diversity of Conopeptides and Conoenzymes from the Venom Duct of the
RT   Marine Cone Snail Conus bayani as Determined from Transcriptomic and
RT   Proteomic Analyses.";
RL   Mar. Drugs 19:0-0(2021).
CC   -!- FUNCTION: Probable toxin. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:33916793}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom duct.
CC       {ECO:0000305|PubMed:33916793}.
CC   -!- MASS SPECTROMETRY: [Conotoxin ba1890.8]: Mass=1890.8; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:33916793};
CC   -!- MASS SPECTROMETRY: [Conotoxin ba1560.9]: Mass=1560.9; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:33916793};
CC   -!- MISCELLANEOUS: The mature peptide does not contain cysteine residue.
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the conotoxin H superfamily. {ECO:0000305}.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Pyrrolidone carboxylic acid; Secreted; Signal;
KW   Toxin.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   PROPEP          23..61
FT                   /evidence="ECO:0000305|PubMed:33916793"
FT                   /id="PRO_0000455000"
FT   PEPTIDE         62..78
FT                   /note="Conotoxin ba1890.8"
FT                   /evidence="ECO:0000269|PubMed:33916793"
FT                   /id="PRO_0000455001"
FT   PEPTIDE         62..75
FT                   /note="Conotoxin ba1560.9"
FT                   /evidence="ECO:0000269|PubMed:33916793"
FT                   /id="PRO_0000455002"
FT   REGION          25..78
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        50..72
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         62
FT                   /note="Pyrrolidone carboxylic acid"
FT                   /evidence="ECO:0000269|PubMed:33916793"
SQ   SEQUENCE   78 AA;  8363 MW;  3A8030A8F5BB608C CRC64;
     MKTSGRLLFL CLAVGLLLES QAHPIADAED ATRNVGSDGT SVELSEILER GQDSSAEKGQ
     RQNDHDVDES GHDIPFPS