ID   CH10_DICDI              Reviewed;         102 AA.
AC   Q54J68;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=10 kDa heat shock protein, mitochondrial;
DE            Short=Hsp10;
DE   AltName: Full=10 kDa chaperonin;
DE   AltName: Full=Chaperonin 10;
DE            Short=CPN10;
GN   Name=hspe1; ORFNames=DDB_G0288265;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Eukaryotic CPN10 homolog which is essential for mitochondrial
CC       protein biogenesis, together with CPN60. Binds to CPN60 in the presence
CC       of Mg-ATP and suppresses the ATPase activity of the latter (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Homohexamer. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GroES chaperonin family. {ECO:0000305}.
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DR   EMBL; AAFI02000109; EAL63314.1; -; Genomic_DNA.
DR   RefSeq; XP_636819.1; XM_631727.1.
DR   AlphaFoldDB; Q54J68; -.
DR   SMR; Q54J68; -.
DR   STRING; 44689.DDB0231250; -.
DR   PaxDb; Q54J68; -.
DR   EnsemblProtists; EAL63314; EAL63314; DDB_G0288265.
DR   GeneID; 8626536; -.
DR   KEGG; ddi:DDB_G0288265; -.
DR   dictyBase; DDB_G0288265; -.
DR   eggNOG; KOG1641; Eukaryota.
DR   HOGENOM; CLU_132825_0_2_1; -.
DR   InParanoid; Q54J68; -.
DR   OMA; KSNENQA; -.
DR   PhylomeDB; Q54J68; -.
DR   PRO; PR:Q54J68; -.
DR   Proteomes; UP000002195; Chromosome 5.
DR   GO; GO:0005759; C:mitochondrial matrix; IBA:GO_Central.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0140662; F:ATP-dependent protein folding chaperone; IEA:InterPro.
DR   GO; GO:0051087; F:chaperone binding; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IBA:GO_Central.
DR   GO; GO:0051082; F:unfolded protein binding; ISS:dictyBase.
DR   GO; GO:0051085; P:chaperone cofactor-dependent protein refolding; IBA:GO_Central.
DR   GO; GO:0006457; P:protein folding; ISS:dictyBase.
DR   CDD; cd00320; cpn10; 1.
DR   Gene3D; 2.30.33.40; -; 1.
DR   InterPro; IPR020818; Chaperonin_GroES.
DR   InterPro; IPR037124; Chaperonin_GroES_sf.
DR   InterPro; IPR011032; GroES-like_sf.
DR   PANTHER; PTHR10772; PTHR10772; 1.
DR   Pfam; PF00166; Cpn10; 1.
DR   PRINTS; PR00297; CHAPERONIN10.
DR   SMART; SM00883; Cpn10; 1.
DR   SUPFAM; SSF50129; SSF50129; 1.
PE   3: Inferred from homology;
KW   Chaperone; Mitochondrion; Reference proteome.
FT   CHAIN           1..102
FT                   /note="10 kDa heat shock protein, mitochondrial"
FT                   /id="PRO_0000328414"
SQ   SEQUENCE   102 AA;  10973 MW;  F0B399A6AE80AF41 CRC64;
     MSGVKKFIPL LDRILVEKIS NQATKTSGGI FIPTNKDAPT NNAKVIAVGT GSVKLDGSFI
     DPIVKEGDIV LINPKARSNT VPWGDKTYHL LSENDILGII EN