ID   CH18_DROSU              Reviewed;         174 AA.
AC   P24514;
DT   01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-1992, sequence version 1.
DT   25-MAY-2022, entry version 52.
DE   RecName: Full=Chorion protein S18;
DE   Flags: Precursor;
GN   Name=Cp18; Synonyms=S18;
OS   Drosophila subobscura (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7241;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2213881; DOI=10.1016/s0022-2836(05)80341-9;
RA   Swimmer C., Fenerjian M.G., Martinez-Cruzado J.C., Kafatos F.C.;
RT   "Evolution of the autosomal chorion cluster in Drosophila. III. Comparison
RT   of the s18 gene in evolutionarily distant species and heterospecific
RT   control of chorion gene amplification.";
RL   J. Mol. Biol. 215:225-235(1990).
CC   -!- FUNCTION: Chorion membrane (egg shell) protein; plays a role in
CC       protecting the egg from the environment. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the chorion protein S15/S18 family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X53423; CAA37508.1; -; Genomic_DNA.
DR   PIR; S13217; S13217.
DR   AlphaFoldDB; P24514; -.
DR   FlyBase; FBgn0012935; Dsub\Cp18.
DR   GO; GO:0042600; C:egg chorion; IEA:InterPro.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR005649; Chorion_2.
DR   Pfam; PF03964; Chorion_2; 1.
PE   3: Inferred from homology;
KW   Secreted; Signal.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255"
FT   CHAIN           18..174
FT                   /note="Chorion protein S18"
FT                   /id="PRO_0000089622"
FT   REGION          154..174
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   174 AA;  17869 MW;  CBEE3C41442B8205 CRC64;
     MMKFMCIFIC AVAAVSASGY GGRRPSYGSA PIGAYAYQVQ PALTVKAIIP SYGGQRGYGH
     NQGGYEAAPI ASAYGNADIG NQYGPVSGSR YGGAPPVDRE AIALAKLALA APSAGGPLVW
     REAPRRVQHA YGPSNYGAPQ QRYARAEEAQ GASAAAASSS VAGVAKKGYR KSSY