ID   CH18_DROVI              Reviewed;         170 AA.
AC   P24515; B4LEM7;
DT   01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-1992, sequence version 1.
DT   03-AUG-2022, entry version 84.
DE   RecName: Full=Chorion protein S18;
DE   Flags: Precursor;
GN   Name=Cp18; Synonyms=S18; ORFNames=GJ13066;
OS   Drosophila virilis (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila.
OX   NCBI_TaxID=7244;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2213881; DOI=10.1016/s0022-2836(05)80341-9;
RA   Swimmer C., Fenerjian M.G., Martinez-Cruzado J.C., Kafatos F.C.;
RT   "Evolution of the autosomal chorion cluster in Drosophila. III. Comparison
RT   of the s18 gene in evolutionarily distant species and heterospecific
RT   control of chorion gene amplification.";
RL   J. Mol. Biol. 215:225-235(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 15010-1051.87;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- FUNCTION: Chorion membrane (egg shell) protein; plays a role in
CC       protecting the egg from the environment. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the chorion protein S15/S18 family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X53421; CAA37500.1; -; Genomic_DNA.
DR   EMBL; CH940647; EDW69112.1; -; Genomic_DNA.
DR   PIR; S13218; S13218.
DR   RefSeq; XP_002046770.1; XM_002046734.2.
DR   AlphaFoldDB; P24515; -.
DR   STRING; 7244.FBpp0227483; -.
DR   EnsemblMetazoa; FBtr0228991; FBpp0227483; FBgn0013070.
DR   GeneID; 6623410; -.
DR   KEGG; dvi:6623410; -.
DR   eggNOG; ENOG502TBAZ; Eukaryota.
DR   HOGENOM; CLU_1541752_0_0_1; -.
DR   InParanoid; P24515; -.
DR   OMA; FMCIFVC; -.
DR   OrthoDB; 1641609at2759; -.
DR   PhylomeDB; P24515; -.
DR   Proteomes; UP000008792; Unassembled WGS sequence.
DR   GO; GO:0042600; C:egg chorion; IEA:InterPro.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR005649; Chorion_2.
DR   Pfam; PF03964; Chorion_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome; Secreted; Signal.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000255"
FT   CHAIN           18..170
FT                   /note="Chorion protein S18"
FT                   /id="PRO_0000089623"
FT   REGION          146..170
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   170 AA;  17570 MW;  A90D02E5BFBB0F85 CRC64;
     MMKFMCIFVC AIAAVSANAY GRQGYGSVPV GGYAYQVQPA LTVKAIVPAG GYGGGSYGGG
     YGNNNYGRSI EVPVSAHYTS SRGYGAAPVD RQAISLAKLS LAAPNAGAPL VWKEPRQIVE
     RSYGPQQSYG QKHSYGYGEQ AQGASAAAAS SSVAGQHSGY KNSGYKNSSY