CH36_DROME
ID CH36_DROME Reviewed; 284 AA.
AC P07182; A4ULY0; Q9W3E6;
DT 01-APR-1988, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2005, sequence version 2.
DT 03-AUG-2022, entry version 140.
DE RecName: Full=Chorion protein S36;
DE Flags: Precursor;
GN Name=Cp36; Synonyms=s36; ORFNames=CG1478;
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=3036489; DOI=10.1002/j.1460-2075.1987.tb04857.x;
RA Spradling A.C., de Cicco D.V., Wakimoto B.T., Levine J.F., Kalfayan L.J.,
RA Cooley L.;
RT "Amplification of the X-linked Drosophila chorion gene cluster requires a
RT region upstream from the s38 chorion gene.";
RL EMBO J. 6:1045-1053(1987).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=17244601; DOI=10.1093/molbev/msm009;
RA Jagadeeshan S., Singh R.S.;
RT "Rapid evolution of outer egg membrane proteins in the Drosophila
RT melanogaster subgroup: a case of ecologically driven evolution of female
RT reproductive traits.";
RL Mol. Biol. Evol. 24:929-938(2007).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley;
RX PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA Venter J.C.;
RT "The genome sequence of Drosophila melanogaster.";
RL Science 287:2185-2195(2000).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=Berkeley;
RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT review.";
RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
CC -!- FUNCTION: Chorion membrane (egg shell) protein; plays a role in
CC protecting the egg from the environment.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- SIMILARITY: Belongs to the chorion protein S36 family. {ECO:0000305}.
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DR EMBL; X05245; CAA28870.1; -; Genomic_DNA.
DR EMBL; EF441648; ABO71689.1; -; Genomic_DNA.
DR EMBL; AE014298; AAF46382.1; -; Genomic_DNA.
DR PIR; S07193; S07193.
DR RefSeq; NP_511087.1; NM_078532.2.
DR AlphaFoldDB; P07182; -.
DR BioGRID; 58246; 31.
DR DIP; DIP-17859N; -.
DR IntAct; P07182; 4.
DR MINT; P07182; -.
DR STRING; 7227.FBpp0071150; -.
DR PaxDb; P07182; -.
DR PRIDE; P07182; -.
DR DNASU; 31787; -.
DR EnsemblMetazoa; FBtr0071203; FBpp0071150; FBgn0000359.
DR GeneID; 31787; -.
DR KEGG; dme:Dmel_CG1478; -.
DR CTD; 31787; -.
DR FlyBase; FBgn0000359; Cp36.
DR VEuPathDB; VectorBase:FBgn0000359; -.
DR eggNOG; ENOG502T6KI; Eukaryota.
DR HOGENOM; CLU_1002086_0_0_1; -.
DR InParanoid; P07182; -.
DR OMA; PYGGSNY; -.
DR OrthoDB; 1414665at2759; -.
DR PhylomeDB; P07182; -.
DR BioGRID-ORCS; 31787; 0 hits in 1 CRISPR screen.
DR GenomeRNAi; 31787; -.
DR PRO; PR:P07182; -.
DR Proteomes; UP000000803; Chromosome X.
DR Bgee; FBgn0000359; Expressed in adult abdomen and 11 other tissues.
DR ExpressionAtlas; P07182; baseline and differential.
DR Genevisible; P07182; DM.
DR GO; GO:0042600; C:egg chorion; IDA:FlyBase.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005213; F:structural constituent of egg chorion; IDA:FlyBase.
DR GO; GO:0007306; P:eggshell chorion assembly; IMP:FlyBase.
DR GO; GO:0007305; P:vitelline membrane formation involved in chorion-containing eggshell formation; IMP:FlyBase.
DR InterPro; IPR008449; Chorion_S36/S28.
DR Pfam; PF05387; Chorion_3; 1.
PE 3: Inferred from homology;
KW Reference proteome; Secreted; Signal.
FT SIGNAL 1..20
FT /evidence="ECO:0000255"
FT CHAIN 21..284
FT /note="Chorion protein S36"
FT /id="PRO_0000089629"
FT REGION 240..284
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 240..259
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 15
FT /note="T -> A (in Ref. 1; CAA28870)"
FT /evidence="ECO:0000305"
FT CONFLICT 35
FT /note="G -> GHG (in Ref. 1; CAA28870)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 284 AA; 29916 MW; 0A1302BEE5992FA4 CRC64;
MQLGLWFGIL AIAATPLVSA NYGPAGGHGH GHGHGQYLSG PNAGLEEYVN VASGGNQQAA
NQIASQAEIQ PTPEEARRLG RVQAQLQALN ADPNYQKLKN SEDIAESLAE TNLASNIRQG
KIKVVSPQFV DQHLFRSLLV PSGHNNHQVI ATQPLPPIIV HQPGAPPAHV NSGPPTVVRG
NPVIYKIKPS VIYQQEVINK VPTPLSLNPV YVKVYKPGKK IEAPLAPVVA PVYSQPREYS
QPQGYGSAGA ASSAAGAASS ADGNAYGNEA PLYNSPAPYG QPNY
