ID   CHBE4_BOMMO             Reviewed;         194 AA.
AC   Q17217; Q99236;
DT   03-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Chorion class B protein ERB4 {ECO:0000303|PubMed:1874417};
DE   AltName: Full=Chorion class B protein 6A2 {ECO:0000303|PubMed:6572954};
DE   Flags: Precursor;
GN   Name=ErB.4 {ECO:0000312|EMBL:CAA41357.1};
OS   Bombyx mori (Silk moth).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC   Bombycidae; Bombycinae; Bombyx.
OX   NCBI_TaxID=7091;
RN   [1] {ECO:0000305, ECO:0000312|EMBL:CAA41357.1}
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND DEVELOPMENTAL STAGE.
RC   STRAIN=703 {ECO:0000312|EMBL:CAA41357.1};
RX   PubMed=1874417; DOI=10.1093/genetics/128.3.595;
RA   Hibner B.L., Burke W.D., Eickbush T.H.;
RT   "Sequence identity in an early chorion multigene family is the result of
RT   localized gene conversion.";
RL   Genetics 128:595-606(1991).
RN   [2] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 1-148, FUNCTION, AND DEVELOPMENTAL STAGE.
RC   TISSUE=Choriogenic follicle {ECO:0000269|PubMed:6572954};
RX   PubMed=6572954; DOI=10.1073/pnas.80.7.1955;
RA   Lecanidou R., Eickbush T.H., Rodakis G.C., Kafatos F.C.;
RT   "Novel B family sequence from an early chorion cDNA library of Bombyx
RT   mori.";
RL   Proc. Natl. Acad. Sci. U.S.A. 80:1955-1959(1983).
CC   -!- FUNCTION: This protein is one of many from the eggshell of the silk
CC       moth. {ECO:0000269|PubMed:6572954}.
CC   -!- DEVELOPMENTAL STAGE: Detected during early choriogenesis and is not
CC       detected after follicle 6. Maximum abundance in follicles 4 and 5.
CC       {ECO:0000269|PubMed:1874417, ECO:0000269|PubMed:6572954}.
CC   -!- SIMILARITY: Belongs to the chorion protein family. {ECO:0000255}.
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DR   EMBL; X58451; CAA41357.1; -; Genomic_DNA.
DR   EMBL; J01023; -; NOT_ANNOTATED_CDS; mRNA.
DR   PIR; A19318; A19318.
DR   PIR; S24297; S24297.
DR   RefSeq; NP_001112382.1; NM_001118910.1.
DR   AlphaFoldDB; Q17217; -.
DR   GeneID; 101740388; -.
DR   KEGG; bmor:101740388; -.
DR   InParanoid; Q17217; -.
DR   Proteomes; UP000005204; Unassembled WGS sequence.
DR   GO; GO:0042600; C:egg chorion; IEA:InterPro.
DR   GO; GO:0005213; F:structural constituent of egg chorion; IEA:InterPro.
DR   GO; GO:0007304; P:chorion-containing eggshell formation; IDA:UniProtKB.
DR   InterPro; IPR002635; Chorion.
DR   Pfam; PF01723; Chorion_1; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome; Repeat; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255, ECO:0000312|EMBL:CAA41357.1"
FT   CHAIN           21..194
FT                   /note="Chorion class B protein ERB4"
FT                   /evidence="ECO:0000269|PubMed:1874417"
FT                   /id="PRO_5000145783"
FT   REGION          22..72
FT                   /note="Left arm"
FT                   /evidence="ECO:0000269|PubMed:6572954"
FT   REGION          73..128
FT                   /note="Central domain"
FT                   /evidence="ECO:0000269|PubMed:6572954"
FT   REGION          129..194
FT                   /note="Right arm (Gly-rich tandem repeats)"
FT                   /evidence="ECO:0000269|PubMed:6572954"
FT   CONFLICT        64
FT                   /note="I -> M (in Ref. 2; J01023)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        69
FT                   /note="Missing (in Ref. 2; J01023)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        148
FT                   /note="I -> T (in Ref. 2; J01023)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   194 AA;  18610 MW;  ABC06ECE0C8EA9F7 CRC64;
     MSSNVIVLCV SALFIQCAVS QCVGRIGSLR GGPFDGWGYD GLGYDGFGIG GWNGRGCGGL
     GDDIAAAAAL GASHGGTLAV VSTSAAPTGL GIASENVYEG SVGVCGNLPF LGTADVAGEF
     PTAGLGGIDY TCGDGAVGIT VENAINGISN VGYGLAPGIV GPAVAAPALG YGPGISSLGY
     NTAGRGCGCG ANYY