CHE1_CHEAL
ID CHE1_CHEAL Reviewed; 168 AA.
AC Q8LGR0;
DT 24-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 03-AUG-2022, entry version 46.
DE RecName: Full=Pollen allergen Che a 1;
DE AltName: Allergen=Che a 1;
DE Flags: Precursor;
OS Chenopodium album (Fat-hen).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC Caryophyllales; Chenopodiaceae; Chenopodioideae; Atripliceae; Chenopodium.
OX NCBI_TaxID=3559;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND PARTIAL PROTEIN SEQUENCE.
RC TISSUE=Pollen;
RX PubMed=11893853; DOI=10.1159/000048168;
RA Barderas R., Villalba M., Lombardero M., Rodriguez R.;
RT "Identification and characterization of Che a 1 allergen from Chenopodium
RT album pollen.";
RL Int. Arch. Allergy Immunol. 127:47-54(2002).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- ALLERGEN: Causes an allergic reaction in human. Binds to IgE.
CC -!- SIMILARITY: Belongs to the Ole e I family. {ECO:0000305}.
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DR EMBL; AY049012; AAL07319.1; -; mRNA.
DR AlphaFoldDB; Q8LGR0; -.
DR SMR; Q8LGR0; -.
DR Allergome; 199; Che a 1.
DR Allergome; 3188; Che a 1.0101.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR InterPro; IPR006040; Allergen_Ole_e_I_CS.
DR InterPro; IPR006041; Pollen_Ole_e1_allergen.
DR PANTHER; PTHR31614; PTHR31614; 1.
DR PROSITE; PS00925; OLEEI; 1.
PE 1: Evidence at protein level;
KW Allergen; Direct protein sequencing; Disulfide bond; Glycoprotein;
KW Secreted; Signal.
FT SIGNAL 1..25
FT CHAIN 26..168
FT /note="Pollen allergen Che a 1"
FT /id="PRO_0000020070"
FT CARBOHYD 64
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT DISULFID 38..109
FT /evidence="ECO:0000250"
FT DISULFID 41..153
FT /evidence="ECO:0000250"
FT DISULFID 62..97
FT /evidence="ECO:0000250"
SQ SEQUENCE 168 AA; 18295 MW; FD7250C6075AE4A5 CRC64;
MAKCQAVFLL VGALCVLSLA GVANAAENHF KVQGMVYCDT CRIQFMTRIS TIMEGATVKL
ECRNITAGTQ TFKAEAVTDK VGQYSIPVNG DFEDDICEIE LVKSPNSECS EVSHDVYAKQ
SAKVSLTSNN GEASDIRSAN ALGFMRKEPL KECPEVLKEL DLYDVKAN