ID   ACEA_KOMXY              Reviewed;         532 AA.
AC   Q44576;
DT   16-OCT-2013, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 48.
DE   RecName: Full=Undecaprenyl-phosphate glucose phosphotransferase;
DE            EC=2.7.8.31;
GN   Name=aceA;
OS   Komagataeibacter xylinus (Gluconacetobacter xylinus).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC   Acetobacteraceae; Komagataeibacter.
OX   NCBI_TaxID=28448;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=C1;
RX   PubMed=8935665; DOI=10.1111/j.1574-6968.1996.tb08092.x;
RA   Griffin A.M., Morris V.J., Gasson M.J.;
RT   "Identification, cloning and sequencing the aceA gene involved in acetan
RT   biosynthesis in Acetobacter xylinum.";
RL   FEMS Microbiol. Lett. 137:115-121(1996).
RN   [2]
RP   FUNCTION.
RX   PubMed=12353627; DOI=10.1271/bbb.66.1677;
RA   Ishida T., Sugano Y., Nakai T., Shoda M.;
RT   "Effects of acetan on production of bacterial cellulose by Acetobacter
RT   xylinum.";
RL   Biosci. Biotechnol. Biochem. 66:1677-1681(2002).
CC   -!- FUNCTION: Involved in the biosynthesis of the exopolysaccharide acetan,
CC       a water-soluble polysaccharide involved in production of bacterial
CC       cellulose (BC). {ECO:0000269|PubMed:12353627}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=di-trans,octa-cis-undecaprenyl phosphate + UDP-alpha-D-glucose
CC         = alpha-D-glucosyl di-trans,octa-cis-undecaprenyl diphosphate + UMP;
CC         Xref=Rhea:RHEA:28126, ChEBI:CHEBI:57865, ChEBI:CHEBI:58885,
CC         ChEBI:CHEBI:60392, ChEBI:CHEBI:61254; EC=2.7.8.31;
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the bacterial sugar transferase family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X93149; CAA63648.1; -; Genomic_DNA.
DR   PIR; T44788; T44788.
DR   AlphaFoldDB; Q44576; -.
DR   SMR; Q44576; -.
DR   PRIDE; Q44576; -.
DR   BioCyc; MetaCyc:MON-15987; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0000271; P:polysaccharide biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR003362; Bact_transf.
DR   InterPro; IPR017475; EPS_sugar_tfrase.
DR   Pfam; PF02397; Bac_transf; 1.
DR   TIGRFAMs; TIGR03025; EPS_sugtrans; 1.
PE   3: Inferred from homology;
KW   Exopolysaccharide synthesis; Glycosyltransferase; Membrane; Transferase;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..532
FT                   /note="Undecaprenyl-phosphate glucose phosphotransferase"
FT                   /id="PRO_0000424202"
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        110..130
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        155..175
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        183..203
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        344..364
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   532 AA;  60276 MW;  E29B672C9F956A64 CRC64;
     MGIISHSIVQ CGKWQAGPAR RQVVFRVHRR CFKMSEALRH LKNGETDLSS LPSGLDSIPR
     RIHTARGVDD SFSYRHPVLP QVVVLSDAFC VCLAVVACIA WQRIYDTPDE LSGALLLANI
     MAAGAFFLFP KNVPLLDIPD ITKVSVQIRY LLPPVAFGEV VFCTVLVMLS WPFGVTVRMG
     MEWLTFVVAI LFVERCVGTY ILHTPTMTRR LARKVAIIGS GSEATQMATR INTRMQRMFR
     LVGTFDDQGG DSDGTVEELV LRAREDHIDA VIICFPPACG QQHVMDVLWR LRGVLADVYV
     VPSLMTEDCH GWPVERFGPF SLTVLQRRPL SEWDMLEKRA FDLTASVLLL LALAPLLTLV
     ALAIKLDSRG PVLFCQPRQG FNNRYFNVFK FRSMYTDMSD LDAARQTSRT DPRVTRIGRW
     IRRLSIDELP QLFNVLRGEM SLVGPRPHAP QTRAGGQLLH EAMEEYVARH RVQPGITGWA
     QINGSRGELV TRDDLCRRVV LDLEYIRAWS IWLDIKIIFL TIKREIFSRN AF