CHED1_BURTA
ID CHED1_BURTA Reviewed; 234 AA.
AC Q2STS7;
DT 03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 24-JAN-2006, sequence version 1.
DT 03-AUG-2022, entry version 79.
DE RecName: Full=Probable chemoreceptor glutamine deamidase CheD 1 {ECO:0000255|HAMAP-Rule:MF_01440};
DE EC=3.5.1.44 {ECO:0000255|HAMAP-Rule:MF_01440};
GN Name=cheD1 {ECO:0000255|HAMAP-Rule:MF_01440}; OrderedLocusNames=BTH_I3178;
OS Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 /
OS E264).
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; pseudomallei group.
OX NCBI_TaxID=271848;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700388 / DSM 13276 / CIP 106301 / E264;
RX PubMed=16336651; DOI=10.1186/1471-2164-6-174;
RA Kim H.S., Schell M.A., Yu Y., Ulrich R.L., Sarria S.H., Nierman W.C.,
RA DeShazer D.;
RT "Bacterial genome adaptation to niches: divergence of the potential
RT virulence genes in three Burkholderia species of different survival
RT strategies.";
RL BMC Genomics 6:174-174(2005).
CC -!- FUNCTION: Probably deamidates glutamine residues to glutamate on
CC methyl-accepting chemotaxis receptors (MCPs), playing an important role
CC in chemotaxis. {ECO:0000255|HAMAP-Rule:MF_01440}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + L-glutaminyl-[protein] = L-glutamyl-[protein] + NH4(+);
CC Xref=Rhea:RHEA:16441, Rhea:RHEA-COMP:10207, Rhea:RHEA-COMP:10208,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:29973,
CC ChEBI:CHEBI:30011; EC=3.5.1.44; Evidence={ECO:0000255|HAMAP-
CC Rule:MF_01440};
CC -!- SIMILARITY: Belongs to the CheD family. {ECO:0000255|HAMAP-
CC Rule:MF_01440}.
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DR EMBL; CP000086; ABC39548.1; -; Genomic_DNA.
DR RefSeq; WP_011402604.1; NZ_CP008786.1.
DR AlphaFoldDB; Q2STS7; -.
DR SMR; Q2STS7; -.
DR PRIDE; Q2STS7; -.
DR EnsemblBacteria; ABC39548; ABC39548; BTH_I3178.
DR GeneID; 66545527; -.
DR KEGG; bte:BTH_I3178; -.
DR HOGENOM; CLU_087854_0_0_4; -.
DR OMA; VGMADLN; -.
DR OrthoDB; 1863047at2; -.
DR Proteomes; UP000001930; Chromosome I.
DR GO; GO:0050568; F:protein-glutamine glutaminase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-UniRule.
DR CDD; cd16352; CheD; 1.
DR Gene3D; 3.30.1330.200; -; 1.
DR HAMAP; MF_01440; CheD; 1.
DR InterPro; IPR038592; CheD-like_sf.
DR InterPro; IPR005659; Chemorcpt_Glu_NH3ase_CheD.
DR InterPro; IPR011324; Cytotoxic_necrot_fac-like_cat.
DR PANTHER; PTHR35147; PTHR35147; 1.
DR Pfam; PF03975; CheD; 1.
DR SUPFAM; SSF64438; SSF64438; 1.
PE 3: Inferred from homology;
KW Chemotaxis; Hydrolase.
FT CHAIN 1..234
FT /note="Probable chemoreceptor glutamine deamidase CheD 1"
FT /id="PRO_0000251017"
FT REGION 183..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 183..199
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 234 AA; 25594 MW; E8A154DEF56004B6 CRC64;
MSGLPIATNL YFDAHFHRRG VKLLPNEFYT TREDMVLVTV LGSCVAACLH DPIARIGGMN
HFMLPDDGAD PSAAASESMR YGAYAMEVLI NELIKAGGRR ERFEAKVFGG AAVLAGMTTI
NIGDRNADFV RRYLALERIR ITAEDLQGVH PRKVAFMPHT GQAMVKKLRV QAPDVAEREA
ALAREAAGPR GERAARARPR VELFGTPAPK AQATPRIELF GTRATQPATR KQEA