ID   CHED1_GEOSL             Reviewed;         201 AA.
AC   Q74F83;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   29-MAY-2013, sequence version 2.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Probable chemoreceptor glutamine deamidase CheD 1 {ECO:0000255|HAMAP-Rule:MF_01440};
DE            EC=3.5.1.44 {ECO:0000255|HAMAP-Rule:MF_01440};
GN   Name=cheD1 {ECO:0000255|HAMAP-Rule:MF_01440}; Synonyms=cheD64H;
GN   OrderedLocusNames=GSU0726;
OS   Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales;
OC   Geobacteraceae; Geobacter.
OX   NCBI_TaxID=243231;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51573 / DSM 12127 / PCA;
RX   PubMed=14671304; DOI=10.1126/science.1088727;
RA   Methe B.A., Nelson K.E., Eisen J.A., Paulsen I.T., Nelson W.C.,
RA   Heidelberg J.F., Wu D., Wu M., Ward N.L., Beanan M.J., Dodson R.J.,
RA   Madupu R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S.,
RA   Gwinn M.L., Kolonay J.F., Sullivan S.A., Haft D.H., Selengut J.,
RA   Davidsen T.M., Zafar N., White O., Tran B., Romero C., Forberger H.A.,
RA   Weidman J.F., Khouri H.M., Feldblyum T.V., Utterback T.R., Van Aken S.E.,
RA   Lovley D.R., Fraser C.M.;
RT   "Genome of Geobacter sulfurreducens: metal reduction in subsurface
RT   environments.";
RL   Science 302:1967-1969(2003).
CC   -!- FUNCTION: Probably deamidates glutamine residues to glutamate on
CC       methyl-accepting chemotaxis receptors (MCPs), playing an important role
CC       in chemotaxis. {ECO:0000255|HAMAP-Rule:MF_01440}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + L-glutaminyl-[protein] = L-glutamyl-[protein] + NH4(+);
CC         Xref=Rhea:RHEA:16441, Rhea:RHEA-COMP:10207, Rhea:RHEA-COMP:10208,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:29973,
CC         ChEBI:CHEBI:30011; EC=3.5.1.44; Evidence={ECO:0000255|HAMAP-
CC         Rule:MF_01440};
CC   -!- SIMILARITY: Belongs to the CheD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01440}.
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DR   EMBL; AE017180; AAR34056.2; -; Genomic_DNA.
DR   RefSeq; NP_951783.2; NC_002939.5.
DR   RefSeq; WP_010941388.1; NC_002939.5.
DR   AlphaFoldDB; Q74F83; -.
DR   SMR; Q74F83; -.
DR   STRING; 243231.GSU0726; -.
DR   PRIDE; Q74F83; -.
DR   EnsemblBacteria; AAR34056; AAR34056; GSU0726.
DR   KEGG; gsu:GSU0726; -.
DR   PATRIC; fig|243231.5.peg.724; -.
DR   eggNOG; COG1871; Bacteria.
DR   HOGENOM; CLU_087854_0_0_7; -.
DR   InParanoid; Q74F83; -.
DR   Proteomes; UP000000577; Chromosome.
DR   GO; GO:0050568; F:protein-glutamine glutaminase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-UniRule.
DR   CDD; cd16352; CheD; 1.
DR   Gene3D; 3.30.1330.200; -; 1.
DR   HAMAP; MF_01440; CheD; 1.
DR   InterPro; IPR038592; CheD-like_sf.
DR   InterPro; IPR005659; Chemorcpt_Glu_NH3ase_CheD.
DR   InterPro; IPR011324; Cytotoxic_necrot_fac-like_cat.
DR   PANTHER; PTHR35147; PTHR35147; 1.
DR   Pfam; PF03975; CheD; 1.
DR   SUPFAM; SSF64438; SSF64438; 1.
PE   3: Inferred from homology;
KW   Chemotaxis; Hydrolase; Reference proteome.
FT   CHAIN           1..201
FT                   /note="Probable chemoreceptor glutamine deamidase CheD 1"
FT                   /id="PRO_0000251035"
SQ   SEQUENCE   201 AA;  22413 MW;  B7333DB64753E6D2 CRC64;
     MRHQRLEGRH IIRIAPGEYH VTTGGGVIST LLGSCVAACL FDSESGVAGM NHFLLSNHRY
     SRTMPFCFTE AGRYGIHSME LLINSLMRHG ARRENLRAKA FGGASILVNR AEVGNFSCVG
     SVNARFVREF LANEGIPLLS ADLEGERGRV IYFDTTDFSV FVRKIRLQRS LVVAKRDRNV
     WEHGVQAHDV EPDSVDLWLP G