ID   CHED2_GEOSL             Reviewed;         160 AA.
AC   Q74E20;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Probable chemoreceptor glutamine deamidase CheD 2 {ECO:0000255|HAMAP-Rule:MF_01440};
DE            EC=3.5.1.44 {ECO:0000255|HAMAP-Rule:MF_01440};
GN   Name=cheD2 {ECO:0000255|HAMAP-Rule:MF_01440}; OrderedLocusNames=GSU1144;
OS   Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales;
OC   Geobacteraceae; Geobacter.
OX   NCBI_TaxID=243231;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51573 / DSM 12127 / PCA;
RX   PubMed=14671304; DOI=10.1126/science.1088727;
RA   Methe B.A., Nelson K.E., Eisen J.A., Paulsen I.T., Nelson W.C.,
RA   Heidelberg J.F., Wu D., Wu M., Ward N.L., Beanan M.J., Dodson R.J.,
RA   Madupu R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S.,
RA   Gwinn M.L., Kolonay J.F., Sullivan S.A., Haft D.H., Selengut J.,
RA   Davidsen T.M., Zafar N., White O., Tran B., Romero C., Forberger H.A.,
RA   Weidman J.F., Khouri H.M., Feldblyum T.V., Utterback T.R., Van Aken S.E.,
RA   Lovley D.R., Fraser C.M.;
RT   "Genome of Geobacter sulfurreducens: metal reduction in subsurface
RT   environments.";
RL   Science 302:1967-1969(2003).
CC   -!- FUNCTION: Probably deamidates glutamine residues to glutamate on
CC       methyl-accepting chemotaxis receptors (MCPs), playing an important role
CC       in chemotaxis. {ECO:0000255|HAMAP-Rule:MF_01440}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + L-glutaminyl-[protein] = L-glutamyl-[protein] + NH4(+);
CC         Xref=Rhea:RHEA:16441, Rhea:RHEA-COMP:10207, Rhea:RHEA-COMP:10208,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:29973,
CC         ChEBI:CHEBI:30011; EC=3.5.1.44; Evidence={ECO:0000255|HAMAP-
CC         Rule:MF_01440};
CC   -!- SIMILARITY: Belongs to the CheD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01440}.
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DR   EMBL; AE017180; AAR34520.2; -; Genomic_DNA.
DR   RefSeq; NP_952197.2; NC_002939.5.
DR   RefSeq; WP_010941805.1; NC_002939.5.
DR   AlphaFoldDB; Q74E20; -.
DR   SMR; Q74E20; -.
DR   STRING; 243231.GSU1144; -.
DR   EnsemblBacteria; AAR34520; AAR34520; GSU1144.
DR   KEGG; gsu:GSU1144; -.
DR   PATRIC; fig|243231.5.peg.1140; -.
DR   eggNOG; COG1871; Bacteria.
DR   HOGENOM; CLU_087854_1_0_7; -.
DR   InParanoid; Q74E20; -.
DR   OMA; RIGGMCH; -.
DR   Proteomes; UP000000577; Chromosome.
DR   GO; GO:0050568; F:protein-glutamine glutaminase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-UniRule.
DR   CDD; cd16352; CheD; 1.
DR   Gene3D; 3.30.1330.200; -; 1.
DR   HAMAP; MF_01440; CheD; 1.
DR   InterPro; IPR038592; CheD-like_sf.
DR   InterPro; IPR005659; Chemorcpt_Glu_NH3ase_CheD.
DR   InterPro; IPR011324; Cytotoxic_necrot_fac-like_cat.
DR   PANTHER; PTHR35147; PTHR35147; 1.
DR   Pfam; PF03975; CheD; 1.
DR   SUPFAM; SSF64438; SSF64438; 1.
PE   3: Inferred from homology;
KW   Chemotaxis; Hydrolase; Reference proteome.
FT   CHAIN           1..160
FT                   /note="Probable chemoreceptor glutamine deamidase CheD 2"
FT                   /id="PRO_0000251036"
SQ   SEQUENCE   160 AA;  17495 MW;  8DA4F0F973F9121A CRC64;
     MTARHPKLPH VYLKPGEFHF ATKPTVVTTV LGSCVSVTMF DVFSRTAAIC HALLPDGPRD
     DVFRYVDSSI IRMLEMFMSR GITPRQLQVK LFGGSDMLGA TASRPGVGSR NVDIARQVLA
     AEGLEVAAAD VGGTRGRKLF FYTHTGEVLL KRLNRTEADS