ID   CHED3_GEOSL             Reviewed;         162 AA.
AC   Q747R4;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 88.
DE   RecName: Full=Probable chemoreceptor glutamine deamidase CheD 3 {ECO:0000255|HAMAP-Rule:MF_01440};
DE            EC=3.5.1.44 {ECO:0000255|HAMAP-Rule:MF_01440};
GN   Name=cheD3 {ECO:0000255|HAMAP-Rule:MF_01440}; OrderedLocusNames=GSU3201;
OS   Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales;
OC   Geobacteraceae; Geobacter.
OX   NCBI_TaxID=243231;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51573 / DSM 12127 / PCA;
RX   PubMed=14671304; DOI=10.1126/science.1088727;
RA   Methe B.A., Nelson K.E., Eisen J.A., Paulsen I.T., Nelson W.C.,
RA   Heidelberg J.F., Wu D., Wu M., Ward N.L., Beanan M.J., Dodson R.J.,
RA   Madupu R., Brinkac L.M., Daugherty S.C., DeBoy R.T., Durkin A.S.,
RA   Gwinn M.L., Kolonay J.F., Sullivan S.A., Haft D.H., Selengut J.,
RA   Davidsen T.M., Zafar N., White O., Tran B., Romero C., Forberger H.A.,
RA   Weidman J.F., Khouri H.M., Feldblyum T.V., Utterback T.R., Van Aken S.E.,
RA   Lovley D.R., Fraser C.M.;
RT   "Genome of Geobacter sulfurreducens: metal reduction in subsurface
RT   environments.";
RL   Science 302:1967-1969(2003).
CC   -!- FUNCTION: Probably deamidates glutamine residues to glutamate on
CC       methyl-accepting chemotaxis receptors (MCPs), playing an important role
CC       in chemotaxis. {ECO:0000255|HAMAP-Rule:MF_01440}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=H2O + L-glutaminyl-[protein] = L-glutamyl-[protein] + NH4(+);
CC         Xref=Rhea:RHEA:16441, Rhea:RHEA-COMP:10207, Rhea:RHEA-COMP:10208,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:29973,
CC         ChEBI:CHEBI:30011; EC=3.5.1.44; Evidence={ECO:0000255|HAMAP-
CC         Rule:MF_01440};
CC   -!- SIMILARITY: Belongs to the CheD family. {ECO:0000255|HAMAP-
CC       Rule:MF_01440}.
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DR   EMBL; AE017180; AAR36592.1; -; Genomic_DNA.
DR   RefSeq; NP_954242.1; NC_002939.5.
DR   RefSeq; WP_010943819.1; NC_002939.5.
DR   AlphaFoldDB; Q747R4; -.
DR   SMR; Q747R4; -.
DR   STRING; 243231.GSU3201; -.
DR   EnsemblBacteria; AAR36592; AAR36592; GSU3201.
DR   KEGG; gsu:GSU3201; -.
DR   PATRIC; fig|243231.5.peg.3225; -.
DR   eggNOG; COG1871; Bacteria.
DR   HOGENOM; CLU_087854_2_0_7; -.
DR   InParanoid; Q747R4; -.
DR   OMA; MQAKIFG; -.
DR   Proteomes; UP000000577; Chromosome.
DR   GO; GO:0050568; F:protein-glutamine glutaminase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-UniRule.
DR   CDD; cd16352; CheD; 1.
DR   Gene3D; 3.30.1330.200; -; 1.
DR   HAMAP; MF_01440; CheD; 1.
DR   InterPro; IPR038592; CheD-like_sf.
DR   InterPro; IPR005659; Chemorcpt_Glu_NH3ase_CheD.
DR   InterPro; IPR011324; Cytotoxic_necrot_fac-like_cat.
DR   PANTHER; PTHR35147; PTHR35147; 1.
DR   Pfam; PF03975; CheD; 1.
DR   SUPFAM; SSF64438; SSF64438; 1.
PE   3: Inferred from homology;
KW   Chemotaxis; Hydrolase; Reference proteome.
FT   CHAIN           1..162
FT                   /note="Probable chemoreceptor glutamine deamidase CheD 3"
FT                   /id="PRO_0000251037"
SQ   SEQUENCE   162 AA;  17253 MW;  639D81AB82FBD2C1 CRC64;
     MSRIVSVGIS EFKIASAPTI LMTYGLGSCV GIALHDPVAL TGGLAHTLLP APVRGMDSMV
     KSAKFTCWAV DLMVEELIKC GCVAERLVAK LAGGATMFEP QHRTTHSGIG ERNVTAAKEA
     LERRGIPLVA SDTGDDYGRS LEFNTVTGVI TVRALQRPIK RM