CHED_BURCA
ID CHED_BURCA Reviewed; 247 AA.
AC Q1BRL1;
DT 03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 03-OCT-2006, sequence version 2.
DT 03-AUG-2022, entry version 70.
DE RecName: Full=Probable chemoreceptor glutamine deamidase CheD {ECO:0000255|HAMAP-Rule:MF_01440};
DE EC=3.5.1.44 {ECO:0000255|HAMAP-Rule:MF_01440};
GN Name=cheD {ECO:0000255|HAMAP-Rule:MF_01440}; OrderedLocusNames=Bcen_2847;
OS Burkholderia cenocepacia (strain AU 1054).
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX NCBI_TaxID=331271;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AU 1054;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Lykidis A., LiPuma J.J., Konstantinidis K.,
RA Tiedje J.M., Richardson P.;
RT "Complete sequence of chromosome 1 of Burkholderia cenocepacia AU 1054.";
RL Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Probably deamidates glutamine residues to glutamate on
CC methyl-accepting chemotaxis receptors (MCPs), playing an important role
CC in chemotaxis. {ECO:0000255|HAMAP-Rule:MF_01440}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + L-glutaminyl-[protein] = L-glutamyl-[protein] + NH4(+);
CC Xref=Rhea:RHEA:16441, Rhea:RHEA-COMP:10207, Rhea:RHEA-COMP:10208,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:29973,
CC ChEBI:CHEBI:30011; EC=3.5.1.44; Evidence={ECO:0000255|HAMAP-
CC Rule:MF_01440};
CC -!- SIMILARITY: Belongs to the CheD family. {ECO:0000255|HAMAP-
CC Rule:MF_01440}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABF77744.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; CP000378; ABF77744.1; ALT_INIT; Genomic_DNA.
DR RefSeq; WP_011546710.1; NC_008060.1.
DR AlphaFoldDB; Q1BRL1; -.
DR SMR; Q1BRL1; -.
DR EnsemblBacteria; ABF77744; ABF77744; Bcen_2847.
DR KEGG; bcn:Bcen_2847; -.
DR HOGENOM; CLU_087854_0_0_4; -.
DR OMA; VGMADLN; -.
DR GO; GO:0050568; F:protein-glutamine glutaminase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-UniRule.
DR CDD; cd16352; CheD; 1.
DR Gene3D; 3.30.1330.200; -; 1.
DR HAMAP; MF_01440; CheD; 1.
DR InterPro; IPR038592; CheD-like_sf.
DR InterPro; IPR005659; Chemorcpt_Glu_NH3ase_CheD.
DR InterPro; IPR011324; Cytotoxic_necrot_fac-like_cat.
DR PANTHER; PTHR35147; PTHR35147; 1.
DR Pfam; PF03975; CheD; 1.
DR SUPFAM; SSF64438; SSF64438; 1.
PE 3: Inferred from homology;
KW Chemotaxis; Hydrolase.
FT CHAIN 1..247
FT /note="Probable chemoreceptor glutamine deamidase CheD"
FT /id="PRO_0000251012"
FT REGION 204..247
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 247 AA; 26726 MW; 14A3319234A6D2FC CRC64;
MSALLIATNR YFDNHFERPG VKLLPNEFYT TAEDMVLMTV LGSCVAACLH DPYAGIGGMN
HFMLPDDGAD PGAAASESMR YGAYAMEVLI NELIKAGGRR ERFEAKVFGG AAVLAGMTTI
NIGDRNADFV RRYLALERIR ITAEDLQGVH PRKVAFMPHS GRAMVKKLRL QVPGVTEREA
ALAREADRLR AARTRAQVEL FAAKRPAAPQ PARPRIELFG GRGTAPGAGS PSAGSPYAAN
LSRKQEA